Depresh Mode with John Moe

Maximum Fun

Health & Fitness, John Moe, Interview, Comedy Interviews, Comedy, Mental Health

4.9 • 854 Ratings

Overview

Join host John Moe (The Hilarious World of Depression) for honest, relatable, and, yes, sometimes funny conversations about mental health. Hear from comedians, musicians, authors, actors, and other top names in entertainment and the arts about living with depression, anxiety, and many other common disorders. Find out what they’ve done to address it, what worked, and what didn’t. Depresh Mode also features useful insights on mental health issues with experts in the field. It’s honest talk from people who have been there and know their stuff. No shame, no stigma, and more laughs than you might expect.

293 Episodes

Blake Mycoskie Helped the World, Got Rich, Retired to a Life of Ease, Then Fell Apart

The TOMS Shoes founder shares his story of highs, lows, and a new podcast.

Transcribed - Published: 1 June 2026

An Episode About the Grind, Singer Zayna Youssef of Sweet Pill, and YOU

Her band was about to set out on a huge tour but canceled it because of a health crisis.

Transcribed - Published: 25 May 2026

Terrifying Times for Immigrants in America and Cristina Jimínez is Incredibly Hopeful

The immigration advocate, author, and MacArthur recipient talks mental health and positive signs.

Transcribed - Published: 18 May 2026

Claude Steele on Churn, the Awkward Social Distress That Divides Us All

The eminent social psychologist explains the effects of a situation you have definitely found yourself in.

Transcribed - Published: 11 May 2026

Connecting Childhood Events To Your Stress Issues Today with Benjamin Wagner

His new documentary, Friends & Neighbors, gets to the bottom of that.

Transcribed - Published: 4 May 2026

Sampler Episode Depresh Meals

Get a little taste of our bonus content on how to get good food in you when depresh is crashing hard.

Transcribed - Published: 1 May 2026

Bonus mini-sode: Checking In with Bill Corbett

One of the best things you can do for mental health and community is a simple “How you doing?”

Transcribed - Published: 30 April 2026

Bonus Mini-Sode: A Dramatic Reading by Helen Hong and Interview with Playwright Sunny Kase

A surprisingly artsy approach to the biggest topic on our minds right now.

Transcribed - Published: 29 April 2026

Casters on Casters: John Moe and Brenda Snell

It's MaxFunDrive. And here, for the first time, we give you an exclusive look (well, listen) at the craft of podcasting: presenting Casters on Casters.

Transcribed - Published: 28 April 2026

Andy Richter on Divorce, Dating, Depression, and Dancing with the Stars

It's not a sequel but this time, Andy Richter Controls A Whole New Universe

Transcribed - Published: 27 April 2026

Bonus mini-sode: Checking In with Felicia Day

One of the best things you can do for mental health and community is a simple “How you doing?”

Transcribed - Published: 23 April 2026

BONUS CONTENT PREVIEW: All-Star Sad Songs That Make You Feel Better with Neko Case, Gavin Rossdale, and more

A sneak preview of this year’s bonus content special: Friends of the show take you through some feel bad / feel good tunes.

Transcribed - Published: 21 April 2026

Jimmy Pardo on Being Funny, Depression, Anxiety, Trauma, Alcoholism, Contentment, and Being Funny Some More

Never Not Funny is 20 years old and Jimmy looks back on his road to better mental health.

Transcribed - Published: 20 April 2026

Joshua Roman on Long Covid, Cello, Charging Hard, and Brick Walls

The superstar cellist put constant effort into accomplishing more. Until he couldn’t.

Transcribed - Published: 13 April 2026

Featuring Proxy with Yowei Shaw: Is it time to break up the band?

A story about friendship, loyalty, and the quiet heartbreak of letting go of something that once held you together.

Transcribed - Published: 6 April 2026

Annabelle Gurwitch: Author, Actor, Unexpectedly Still Alive

She received a cancer diagnosis years ago but the meds are working. For now.

Transcribed - Published: 30 March 2026

Taking Small Steps That Form Great Strides with Eric Zimmer

The author and podcast host has advice on an incremental approach to better health.

Transcribed - Published: 23 March 2026

Bonus Episode from In This Family: Ka Vang on War in Southeast Asia, ICE in Minnesota, and Mental Health Echoes

A conversation about what gets handed down across the world, across the world, and across generations.

Transcribed - Published: 18 March 2026

Bubbles of Love: Your Burnout Treatment, with Emily Nagoski

She literally wrote the book on burnout and says it’s real, it’s dangerous, and you can fight it

Transcribed - Published: 16 March 2026

Group Therapy Royalty and First-Time Movie Star Elliot Zeisel From GROUP

He’s been leading groups for decades and now plays a facilitator with improvised dialogue

Transcribed - Published: 9 March 2026

Jonathan Edward Durham Was In Horrible Mental Shape But Didn’t Realize It

The novelist and hugely popular online writer shares insight on his road to feeling better.

Transcribed - Published: 2 March 2026

Huge Scientific Breakthroughs Are Changing How You’ll Think About Eating Disorders

Movie and TV star Alexandra Paul offers her own journey through bulimia to recovery

Transcribed - Published: 23 February 2026

Are Dating Apps a Mental Health Grenade? And, How Are Kids Doing in ICE-Era Minnesota?

Conversations with relationship researcher Liesel Sharabi and children’s mental health expert Dr. Sarah Jerstad

Transcribed - Published: 16 February 2026

Niko Stratis on Dad Rock, Glasswork, Depression, Addiction, and Becoming Herself

The Canadian author was buoyed and inspired by music through a difficult journey of realizing who she was.

Transcribed - Published: 9 February 2026

SPECIAL EPISODE: Mental Health and ICE in Minnesota

A talk with NAMI Minnesota’s Executive Director Marcus Schmit

Transcribed - Published: 6 February 2026

Amanda Knox on Facing Her Prosecutor, Her Past, Her Trauma, and Her Future

The wrongfully convicted activist and author talks about going back to Italy and who she has become.

Transcribed - Published: 2 February 2026

Intentionally Blunt and Very Useful Talk About Suicide with Clancy Martin

Suicidality is a deadly condition and we take it on with honesty, heart, and a little existentialism

Transcribed - Published: 26 January 2026

Stephanie Foo on Complex PTSD, Finding Recovery, and This American Life

The author and radio producer investigates and reveals a very painful childhood

Transcribed - Published: 19 January 2026

A.J. Daulerio on Bipolar, Substances, Depression, Suicide, and the Psychic Weight of Hulk Hogan

The former Gawker and Deadspin editor is in a better, cleaner place but still struggles as we all often do.

Transcribed - Published: 12 January 2026

Two Truths To Make 2026 a Better Mental Health Year

John Moe explains that life can be contradictory and that’s a good thing.

Transcribed - Published: 5 January 2026

Mike Doughty Was Recently Hospitalized for Depression Twice. It Helped.

The acclaimed singer-songwriter opens up for the first time about a dark period.

Transcribed - Published: 29 December 2025

Tom Johnson Advised LBJ, Ran CNN, and Drove Himself to Severe Depression

The 84-year-old political veteran and media icon opens up about his career, mental health, and regrets.

Transcribed - Published: 22 December 2025

Anger: Let’s Talk About It, Learn About It, Not Fear It, Use It For Good

The Anger Professor, Dr. Ryan Martin, joins us to demystify and better harness anger

Transcribed - Published: 15 December 2025

Unemployment Hurts Mental Health, Horror Movies Might Help It. Really!

Coping tips for the jobless and a look at a unique support group that uses very scary movies.

Transcribed - Published: 8 December 2025

Maureen Johnson Became Friends with Her Anxiety Monster

The prolific, bestselling YA author shares tales of her anxiety and her teen detective’s.

Transcribed - Published: 1 December 2025

A Holiday Family Survival Mini-sode

Some tips from In This Family for getting along and getting through

Transcribed - Published: 26 November 2025

Esmé Weijun Wang’s Mind Convinced Her She Was Dead and In the Afterlife

The author of The Collected Schizophrenias shares an unusual mental health journey

Transcribed - Published: 24 November 2025

Is Your Mental Health Diagnosis an Identity or Something More Meaningless?

Author Sarah Fay says no mental health diagnosis is scientifically valid.

Transcribed - Published: 17 November 2025

The Personal Side of Huge Cuts to Addiction, Suicide Prevention, and Mental Health Programs

O. Rose Broderick from Stat unpacks what the budget and staffing slashes will mean

Transcribed - Published: 10 November 2025

Seasonal Affective Disorder and Why It Sucks So Bad

Handy information about the mental health phenomenon and a new name

Transcribed - Published: 3 November 2025

Is Whiteness a Mental Health Problem? Dr. Jonathan Mathias Lassiter Thinks So.

He’s the author of the new book How I Know White People Are Crazy and Other Stories

Transcribed - Published: 27 October 2025

Is the U.S. Government Going To Take Away Your Antidepressants?

Maybe not yet but the fact that it’s an issue is reason to learn a lot more and fast.

Transcribed - Published: 20 October 2025

P.E. Moskowitz on Whether Your Mind is Broken or the World Is

The author and journalist explores drugs, trauma, and different ways to look at mental health

Transcribed - Published: 13 October 2025

Kendall Toole Gets Knocked Down, Never Knocked Out

The mental health advocate and former Peloton star opens up about dark times and finding resilience.

Transcribed - Published: 6 October 2025

Bruce Springsteen as Over-The-Counter Depression Treatment

Anne Abel’s life was changed by a Springsteen concert. So she flew to Australia for eight more.

Transcribed - Published: 29 September 2025

Emma Swift Had a Complete Mental Breakdown. Found Health. Made Music About It.

The Nashville-based singer-songwriter’s new album, The Resurrection Game, goes to very dark and very real places.

Transcribed - Published: 22 September 2025

Sycophantic Chatbots and Alarming Cases of “AI Psychosis”

Reporter Maggie Harrison Dúpre on the unregulated and potentially dangerous world of AI

Transcribed - Published: 15 September 2025

Alex Edelman on ADHD, Grief, Infiltrating White Nationalists, and The Paper

The Emmy and Tony-winning comedian and actor in a broad illuminating conversation

Transcribed - Published: 8 September 2025

Better Home Design for Better Mental Health with Dr. Beverly Walpole

Plus, a brief rundown on why host John Moe does what he does on this show

Transcribed - Published: 1 September 2025

Denise Winkelman: Comedian/Trans Woman/Former Pro Wrestler/Chronic Pain Sufferer

“Bougie on a Budget”, her debut special, is now streaming

Transcribed - Published: 25 August 2025

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