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MeSsy with Christina Applegate & Jamie Lynn Sigler

MeSsy with Christina Applegate & Jamie Lynn Sigler

Wishbone Production

Personal Journals, Health & Fitness, Society & Culture

4.93.7K Ratings

Overview

On this podcast, Christina Applegate and Jamie Lynn Sigler get vulnerable about the curveballs that life can throw…theirs just happens to be MS. Join them each week as they self-reflect, learn, laugh, and grow through their own raw and often-times hilarious conversations with each other, friends, co-stars, and the people that keep them going through the messiness of life.

114 Episodes

Aida Turturro

This week, Jamie sits down with the one and only Aida Turturro. They reflect on their years together on The Sopranos, and Aida discusses living with rheumatoid arthritis since childhood, perspective, and finding gratitude during difficult times. Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This episode is sponsored by: Novartis in neuroscience - Our ambition is to create a transformational impact for people living with severe neurological conditions and their caregivers by discovering, developing and delivering innovative medicines that change the course of disease progression. Honeylove - Save 20% Off Honeylove by going to https://honeylove.com/messy #honeylovepod Q30 - For a FREE sleeve with your order, head to https://Q30.com/MESSY and use code MESSY. Ridge - Upgrade your wallet today! Get up to 40% off @Ridge during their Father’s Day Sale when you go to https://www.Ridge.com/MESSY  #Ridgepod

Transcribed - Published: 2 June 2026

What the F*ck Is Normal Anyway?

This week, Jamie reads listener emails and discusses what it means to feel seen, the complicated balance between grief and gratitude, and why you don’t have to be “perpetually positive” to keep moving forward. Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This episode is sponsored by: Novartis in neuroscience - Our ambition is to create a transformational impact for people living with severe neurological conditions and their caregivers by discovering, developing and delivering innovative medicines that change the course of disease progression. MudWtr - Start your new morning ritual & get up to 43% off your @MUDWTR with code MESSY at  https://mudwtr.com/messy! #mudwtrpod OneSkin - Get 15% off OneSkin with the code MESSY at https://www.oneskin.co/MESSY #oneskinpod Rythm - Right now, Rythm is offering our listeners 15% off your first month and free shipping at https://rythm.health/messy   Stop guessing, start testing. Rythm DOT HEALTH slash messy  NOCD - If you're struggling with OCD or unrelenting intrusive thoughts, NOCD can help. Book a free 15 minute call to get started: https://learn.nocd.com/messy Veracity - For up to 65% off your order, head to https://VeracityHealth.co and use code MESSY.

Transcribed - Published: 26 May 2026

Lena Hall

This week, Jamie is joined by Tony Award-winning actress and singer Lena Hall. They discuss being present in grief, the power of healing, finding your way back to yourself, and more. Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This episode is sponsored by: Novartis in neuroscience - Our ambition is to create a transformational impact for people living with severe neurological conditions and their caregivers by discovering, developing and delivering innovative medicines that change the course of disease progression. Ridge - Upgrade your wallet today! Get up to 40% off @Ridge during their Father’s Day Sale when you go to https://www.Ridge.com/MESSY  #Ridgepod Q30 - For a FREE sleeve with your order, head to  https://Q30.com/MESSY  and use code MESSY.  Lola - Get 40% off select Lola Blankets products at https://Lolablankets.com by using code MESSY at checkout. Experience the world’s #1 blanket with Lola Blankets. k18 - Shop at Sephora or get 10% off your first purchase at https://k18hair.com with code MESSY. That’s code MESSY at https://k18hair.com Zoc Doc - Stop putting off those doctors appointments and go to https://Zocdoc.com/MESSY to find and instantly book a doctor you love today.

Transcribed - Published: 19 May 2026

Revisiting Our Convo with Martin Short

In honor of 'Marty, Life is Short,' we are revisiting our conversation with Martin Short. He reminisces, shares funny stories, discusses colonoscopy parties, and more. Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch Novartis in neuroscience - Our ambition is to create a transformational impact for people living with severe neurological conditions and their caregivers by discovering, developing and delivering innovative medicines that change the course of disease progression. Jones Road - Use code MESS at https://jonesroadbeauty.com to get a Free Gift with your first purchase! #JonesRoadBeauty #ad NOCD - Go to https://NOCD.com to book a free 15-minute call.  OneSkin - Get 15% off OneSkin with the code MESSY at https://www.oneskin.co/MESSY #oneskinpod

Transcribed - Published: 12 May 2026

A Conversation with Jamie’s Therapist

This week, Jamie sits down with her therapist, Ana Maria Rodriguez, who is a licensed clinical mental health therapist and the founder and owner of Selva Wellness Collective. They discuss how she helped Jamie through processing what came up while writing her memoir, the way the body stores trauma, ketamine therapy, and much more. Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This episode is sponsored by: Novartis in neuroscience - Our ambition is to create a transformational impact for people living with severe neurological conditions and their caregivers by discovering, developing and delivering innovative medicines that change the course of disease progression.Honey - loveSave 20% Off Honeylove by going to https://honeylove.com/messy #honeylovepod Fatty15 - Get an additional 15% off their 90-day subscription Starter Kit by going to https://fatty15.com/messy and using code MESSY at checkout.

Transcribed - Published: 5 May 2026

The Friendship Episode

This week, Jamie is joined by her two best friends, Becca Tobin and Odette Annable. They discuss navigating friendships in all seasons of life, giving grace to yourself and others, finding your people, and more. Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This episode is sponsored by: Novartis in neuroscience Our ambition is to create a transformational impact for people living with severe neurological conditions and their caregivers by discovering, developing and delivering innovative medicines that change the course of disease progression. Tumble - Machine Washable Rugs, Made Better. For a limited time only, our listeners get 10% off + free shipping at https://tumbleliving.com/MESSY #Tumble #ad MudWtr - Start your new morning ritual & get up to 43% off your @MUDWTR with code MESSY at  https://mudwtr.com/MESSY! #mudwtrpod One Skin - Get 15% off OneSkin with the code MESSY at https://www.oneskin.co/MESSY #oneskinpodHoneylove - Save 20% Off Honeylove by going to https://honeylove.com/messy#honeylovepod

Transcribed - Published: 28 April 2026

A Conversation with Jamie's Husband

This week, Jamie is joined by her husband, Cutter Dykstra. They discuss his experience as her partner and caregiver, the role he's played in Jamie's acceptance and outlook, advice for other partners, and more. Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This episode is sponsored by: Novartis in neuroscience - Our ambition is to create a transformational impact for people living with severe neurological conditions and their caregivers by discovering, developing and delivering innovative medicines that change the course of disease progression. Fatty15 - Get an additional 15% off their 90-day subscription Starter Kit by going to ⁠https://fatty15.com/messy⁠ and using code MESSY at checkout. Lola - Get 40% off your entire order at ⁠https://Lolablankets.com⁠ by using code MESSY at checkout. Experience the world’s #1 blanket with Lola Blankets. Honeylove - Save 20% Off Honeylove by going to ⁠https://honeylove.com/messy⁠#honeylovepod Jones Road - Use code MESS at ⁠https://jonesroadbeauty.com⁠ to get a Free Shimmer Face Oil with your first purchase! #JonesRoadBeauty Zoc Doc - Stop putting off those doctors appointments and go to Zocdoc.com/MESSY to find and instantly book a doctor you love today.

Transcribed - Published: 21 April 2026

A MeSsy Update!

We’re taking a short break for the next few weeks while Jamie and Christina focus on their book launches. We’ll be back soon with brand new episodes!

Transcribed - Published: 31 March 2026

Olivia Munn

This week, Christina and Jamie are joined by Olivia Munn. They discuss Olivia’s breast cancer diagnosis, how she was finally able to shed her armor, why you shouldn’t tell someone going through something to look on the bright side, and more.  Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This episode is sponsored by: Veracity - Head to https://VeracityHealth.co and use code MESSY for up to 60% off your order.  Jones Road - Use code MESSY at https://jonesroadbeauty.com to get a Free Shimmer Face Oil with your first purchase #JonesRoadBeauty #ad

Transcribed - Published: 24 March 2026

Carl Radke

This week, Christina and Jamie are joined by Carl Radke, Summer House cast member and  host of "More Life with Carl Radke.” They discuss his journey to sobriety, holding in shame, forgiveness, behind-the-scenes of the show, and more. Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This episode is sponsored by: Wildgrain - Wildgrain is offering our listeners $30 off your first box - PLUS free Croissants for life - when you go to https://Wildgrain.com/MESSY to start your subscription today. Fatty15- Get an additional 15% off their 90-day subscription Starter Kit by going to https://fatty15.com/messy and using code MESSY at checkout. Jones Road - Use code MESSY at https://jonesroadbeauty.com to get a Free Shimmer Face Oil with your first purchase! #JonesRoadBeauty #ad Lola Blankets - Get 40% off select Lola Blankets products at https://Lolablankets.com by using code MESSY at checkout. Experience the world’s #1 blanket with Lola Blankets.

Transcribed - Published: 17 March 2026

How to Heal Your Relationship With Life

This week, Christina and Jamie are joined by Jamie’s friend Ryan Weiss. They discuss how he helped her through a difficult time, the power of dance, emotional avoidance, why it’s so hard to look inward, and more. Check out Ryan's course "How to Be Okay When Things Are Not Okay" and use code MESSY at checkout for 10% off Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This episode is sponsored by: Lola- Get 40% off select Lola Blankets products at https://Lolablankets.com by using code MESSY at checkout. Experience the world’s #1 blanket with Lola Blankets. Zoc Doc - Stop putting off those doctors appointments and go to https://Zocdoc.com/MESSY to find and instantly book a doctor you love today.  One Skin - Get 15% off OneSkin with the code MESSY at https://www.oneskin.co/MESSY #oneskinpod

Transcribed - Published: 10 March 2026

We Don’t Want to Be Defined by This

This week, Christina and Jamie read listener emails and discuss the fragility of life, fighting against your body, and more, Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This episode is sponsored by: Honeylove - Save 20% Off Honeylove by going to https://honeylove.com/MESSY #honeylovepod

Transcribed - Published: 3 March 2026

Kelly Ripa

This week, Christina and Jamie are joined by their friend Kelly Ripa. They discuss Kelly's career and how it began at a toy fair, the processing she had to do while writing her own book, the challenges of playing yourself on television, and much more. Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This episode is sponsored by: Fatty15 - Get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/MESSY and using code MESSY at checkout. Lola - Get 40% off select Lola Blankets products at https://Lolablankets.com by using code MESSY at checkout. Experience the world’s #1 blanket with Lola Blankets. AG1 - For a limited time only, go to https://DRINKAG1.com/MESSY to get a FREE AG1 Flavor Sampler and AGZ Sampler to try all the flavors, plus FREE Vitamin D3+K2 and AG1 Welcome Kit with your first AG1 subscription order!  Honeylove - Save 20% Off Honeylove by going to https://honeylove.com/messy #honeylovepod

Transcribed - Published: 24 February 2026

Stop Talking About It for a Minute

This week, Christina and Jamie read listener emails and discuss skincare products from childhood, crazy animal stories, not thinking too far into the future, and much more.  Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This episode is sponsored by: Wildgrain - Wildgrain is offering our listeners $30 off your first box - PLUS free Croissants for life - when you go to Wildgrain.com/MESSY to start your subscription today. Jones Road - Use code messy at https://jonesroadbeauty.com to get a Free Shimmer Face Oil with your first purchase! #JonesRoadBeauty #adArey - Slow the growth of greys and get 15% off by using code MESSY at https://Arey.com Cheers - Same night out — way better morning with Cheers. For a limited time our listeners are getting 20% off their entire order by using code MESSY at https://CheersHealth.com  #Cheers #ad ZocDoc - Stop putting off those doctors appointments and go to https://Zocdoc.com/MESSY to find and instantly book a doctor you love today.

Transcribed - Published: 17 February 2026

How You Feel on the Inside Can Be Up to You

This week, Christina and Jamie read listener emails and discuss the Married... with Children reunion, catch up on their TV shows, Jamie opens up about a recent experience, and more. Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This episode is sponsored by: Veracity - For up to 45% off your order, head to https://VeracityHealth.co and use code MESSY

Transcribed - Published: 10 February 2026

I Can't Worry About Tomorrow

This week, Christina and Jamie read listener emails and discuss MS fatigue, finding little moments of self care, how to better communicate with friends, and more. Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This episode is sponsored by: Honeylove - Save 20% Off Honeylove by going to https://honeylove.com/messy #honeylovepod Jones Road - Use code messy at https://jonesroadbeauty.com to get a Free Shimmer Face Oil with your first purchase! #JonesRoadBeauty #ad

Transcribed - Published: 3 February 2026

Bobbi Brown

This week, Christina and Jamie are joined by Bobbi Brown. They discuss overcoming obstacles, how to elevate your mood, taking baby steps, and much more.   Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This episode is sponsored by: Lola - Get 40% off your entire order at https://Lolablankets.com by using code MESSY at checkout. Experience the world’s #1 blanket with Lola Blankets. AG1 - Go to https://DRINKAG1.com/MESSY to get their best offer… get a FREE AG1 Flavor Sampler and AGZ Sampler to try all the flavors, plus FREE Vitamin D3+K2 and AG1 Welcome Kit with your first AG1 subscription order!  Warby Parker - MeSsy listeners get 15% off plus free shipping when they buy two or more pairs of prescription glasses at https://WarbyParker.com/MESSY— using our link helps support the show. #WarbyParker #ad Fatty15 - Fatty15 is on a mission to optimize your C15 levels to help support your long-term health and wellness -Get an additional 15% off their 90-day subscription Starter Kit at fatty15.com/MESSY and using code MESSY at checkout.

Transcribed - Published: 27 January 2026

I’m a F**king Warrior

This week, Christina and Jamie read listener emails and discuss Jamie’s recent trip, pregnancy and MS, asking for help, and more. Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This episode is sponsored by: Wildgrain - Wildgrain is offering our listeners $30 off your first box - PLUS free Croissants for life - when you go to Wildgrain.com/MESSY to start your subscription today. Veracity - For up to 45% off your order, head to https://VeracityHealth.co and use code MESSY

Transcribed - Published: 20 January 2026

The Impact of Inflammation with Dr. Will Cole

This week, Christina and Jamie are joined by Dr. Will Cole, a functional medicine expert. They discuss how to calm inflammation, medical gaslighting, the interactions between all our systems, and much more. Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This episode is sponsored by: MudWtr - Start your new morning ritual & get up to 43% off your @MUDWTR with code MESSY at  https://mudwtr.com/messy #mudwtrpod Grow TherapyWhatever challenges you’re facing, Grow Therapy is here to help. Sessions average about $21 with insurance and some pay as little as $0, depending on their plan.  Visit https://GrowTherapy.com/MESSY today to get started.

Transcribed - Published: 13 January 2026

This Is Not Your Fault

This week, Christina and Jamie read listener emails and discuss repeat reality stars, being a mother with MS, not blaming yourself, and more. Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This episode is sponsored by: Honeylove - Save 20% Off Honeylove by going to https://honeylove.com/messy #honeylovepod Jones Road Beauty - Use code Messy at https://jonesroadbeauty.com to get a Free Cool Gloss with your first purchase! #JonesRoadBeauty #ad

Transcribed - Published: 6 January 2026

There’s a Lot of Unknown in Life

This week, Christina and Jamie read listener emails and discuss Christmas elves, setting goals, reclaiming your voice, and more. Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This episode is sponsored by: Calm - Calm has an exclusive offer just for listeners of our show – get 40% off a Calm Premium Subscription at https://calm.com/messy Ridwell - Go to ridwell.com/messy to get $10 off your first pickup or mail-in kit. Because sometimes the best way to do more is just to start with something small that you know makes a difference. Hexclad - Take advantage of HexClad’s Holiday Sale! Head to hexclad.com/MESSY for Up To 50% Off! #hexcladpartner

Transcribed - Published: 30 December 2025

Are You Mad At Me? with Meg Josephson

This week, Christina and Jamie are joined by Meg Josephson, author of “Are You Mad at Me?: How to Stop Focusing on What Others Think and Start Living for You.” They discuss the fawn response, how to start healing, the importance of taking a pause, and more.  Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This episode is sponsored by: ZocDoc - Stop putting off those doctors appointments and go to Zocdoc.com/MESSY to find and instantly book a top-rated doctor today. Wild Grain - Wildgrain is offering our listeners $30 off your first box - PLUS free Croissants in every box - when you go to https://Wildgrain.com/MESSY to start your subscription. iRestore - Unlock your best skin with @iRestorelaser and HUGE savings on the iRestore Illumina Face Mask with code MESSY at https://irestore.com/MESSY #irestorepod Lola Blankets - Lola BlanketsGet 40% off your entire order at Lolablankets.com by using code MESSY at checkout. Experience the world’s #1 blanket with Lola Blankets.

Transcribed - Published: 16 December 2025

Montel Williams

This week Christina and Jamie are joined by Montel Williams. They discuss his experience living with MS, bedside manner, why being ill doesn’t make you weak, and more.  Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This episode is sponsored by: Fatty15 - Fatty15 is on a mission to optimize your C15 levels to help support your long-term health and wellness -Get an additional 15% off their 90-day subscription Starter Kit at fatty15.com/MESSY and using code MESSY at checkout. Tushy - Over 2 Million Butts Love TUSHY. Get 10% off TUSHY with the code MESSY at https://hellotushy.com/MESSY True Classic - Upgrade your wardrobe and save on @trueclassic at trueclassic.com/MESSY #trueclassicpod Ridwell - Head to ridwell.com/messygift. It’s super easy — you can get a digital link to share instantly, or, if you know their address, have a kit mailed straight to your friends and family.  Pro tip: if you’re not using Ridwell yet, treat yourself to one too… maybe that free third one!

Transcribed - Published: 9 December 2025

We're All Crushing It

This week, Christina and Jamie read listener emails and discuss perspective, not stuffing your feelings down, journaling, and much more. Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This episode is sponsored by: Nobl - Don’t miss NOBL’s biggest Sale of the Year! Head to NOBLTravel.com for up to 62% off your entire order! #NOBL #ad Lola Blankets - Get 40% off your entire order at Lolablankets.com by using code MESSY at checkout. Experience the world’s #1 blanket with Lola Blankets. Hollow Socks - For a limited time Hollow Socks is having a Buy 2, Get 2 Free Sale. Head to Hollowsocks.com today to check it out. #Hollow Sockspod Honeylove - Save 20% Off Honeylove by going to honeylove.com/MESSY! #honeylovepod Magic Spoon - Get 5 dollars off your next order at MagicSpoon.com/MESSY. Or look for Magic Spoon on Amazon or in your nearest grocery store.

Transcribed - Published: 2 December 2025

How to Feel Safe in Your Body with Deb Dana (Re-Release)

This week, Christina and Jamie are revisiting their conversation with Deb Dana, LCSW, a clinician and speaker specializing in complex trauma. They discuss how to understand our nervous systems, polyvagal theory, how to feel safe in a body that may feel unsafe, and more. Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This show is sponsored by: Ridwell - Try Ridwell at ridwell.com/messy to get $10 off your first pickup or mail-in kit. iRESTORE -  Illumina Masks:Unlock your best skin with @iRestorelaser and HUGE savings on the iRestore Illumina Face Mask with code MESSY at irestore.com/MESSY! #irestorepod Calm -Calm has an exclusive offer just for listeners of our show– get 40% off a Calm Premium Subscription at calm.com/messy. Honeylove - Save 20% Off Honeylove by going to honeylove.com/MESSY! #honeylovepod Tushy - Over 2 million butts love TUSHY. Get 10% off Tushy with the code MESSY at https://hellotushy.com/messy !

Transcribed - Published: 25 November 2025

You Don’t Deserve to Feel Guilt

This week, Christina and Jamie read listener emails and discuss big feelings, reality dating shows, guilt, and more. Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This episode is sponsored by: Zoc Doc - Stop putting off those doctors appointments and go to Zocdoc.com/MESSY to find and instantly book a top-rated doctor today.  MudWtr - Start your new morning ritual & get up to 43% off your @MUDWTR at mudwtr.com/messy #mudwtrpod Lola Blankets - Get 40% off your entire order at Lolablankets.com by using code MESSY at checkout. Experience the world’s #1 blanket with Lola Blankets. True Classic - Upgrade your wardrobe and save on @trueclassic at trueclassic.com/messy #trueclassicpod iRestore - Unlock your best skin with @iRestorelaser and HUGE savings on the iRestore Illumina Face Mask with code MESSY at irestore.com/messy #irestorepod

Transcribed - Published: 18 November 2025

Best of MeSsy: Edie Falco, Jean Smart, and Katey Sagal

This week, we revisit conversations with three incredible guests: Edie Falco, Jean Smart, and Katey Sagal. Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This episode is sponsored by: Ridwell - Try Ridwell at ridwell.com/messy to get $10 off your first pickup or mail-in kit.Hollow Socks - For a limited time Hollow Socks is having a Buy 3, Get 3 Free Sale. Head to Hollowsocks.com today to check out their huge sale. #Hollow Sockspod MudWtr - Start your new morning ritual & get up to 43% off your @MUDWTR at mudwtr.com/messy! #mudwtrpod Honeylove - Save 20% Off Honeylove by going to honeylove.com/messy. #honeylovepod Cozy Earth - Black Friday has come early at Cozy Earth! Right now, you can stack my code MESSY on top of their sitewide sale — giving you up to 40% off in savings. That’s CozyEarth.com, code MESSY

Transcribed - Published: 11 November 2025

Robert Iler

This week, Christina and Jamie are joined by Robert Iler, who starred on "The Sopranos" with Jamie. They discuss memories from their time on the show, his path to becoming sober, his friendship with Jamie, and much more. Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This episode is sponsored by: Ridge - Upgrade your wallet today! Get 10% Off @Ridge with code MESSY at https://www.Ridge.com/messy  #Ridgepod Fatty15 - Fatty15 is on a mission to optimize your C15 levels to help support your long-term health and wellness -Get an additional 15% off their 90-day subscription Starter Kit at fatty15.com/MESSY and using code MESSY at checkout. Wildgrain - For a limited time, Wildgrain is offering our listeners $30 off your first box - PLUS free Croissants in every box - when you go to Wildgrain.com/MESSY to start your subscription. Magic Spoon - Get 5 dollars off your next order at MagicSpoon.com/MESSY. Or look for Magic Spoon on Amazon or in your nearest grocery store.  Jones Road - Use code MESSY  at jonesroadbeauty.com to get a Free Cool Gloss with your first purchase! These sell out fast so get them while they last! #JonesRoadBeauty #ad

Transcribed - Published: 4 November 2025

How Vulnerable Can I Be? with Craig Thomas

This week Christina and Jamie are joined by Craig Thomas, an author and  Co-Creator, Executive Producer and Writer of How I Met Your Mother. He shares his experience raising a son with Jacobsen Syndrome, discusses the power of storytelling to make people feel less alone, and talks about his new novel, “That’s Not How It Happened.”  Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This episode is sponsored by: AG1 - Go to drinkag1.com/MESSY to get a FREE Frother with your first purchase of AGZ. Ridwell - Try Ridwell at ridwell.com/messy to get $10 off your first pickup or mail-in kit.Calm - Calm has an exclusive offer just for listeners of our show– get 40% off a Calm Premium Subscription at calm.com/messy.

Transcribed - Published: 28 October 2025

We Don’t Move Past It, We Move With It

This week, Christina and Jamie read listener emails and discuss aging, being able to express emotions authentically, where to turn when you’re feeling stuck, and more. Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This episode is sponsored by: Lola - Get 35% off your entire order at Lolablankets.com by using code Messy at checkout. Experience the world’s #1 blanket with Lola Blankets. GoPure - Get the Tighten & Lift Neck Cream and Sculpt & Tone Arm Cream for 57% off OR get 25% off all other products with code MESSY at gopure.com  #goPurepod iRestore - Unlock your best skin with @iRestorelaser and HUGE savings on the iRestore Illumina Face Mask with code MESSY at irestore.com/messy! #irestorepod ZocDoc - Stop putting off those doctors appointments and go to Zocdoc.com/MESSY to find and instantly book a top-rated doctor today.

Transcribed - Published: 21 October 2025

Everybody’s Got Something

This week, Christina and Jamie read listener emails and discuss dynamic disability, not being alone in your struggles, the meaning we attach to things, and more. Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This episode is sponsored by: Ridwell - Try Ridwell at ridwell.com/messy to get $10 off your first pickup or mail-in kit. Mudwtr - Get up to 43% off your entire order, plus free shipping and a free rechargeable frother when you use code MESSY at mudwtr.com Honeylove - Treat yourself to the most comfortable and innovative bras on earth and save 20% Off sitewide at honeylove.com/MESSY Cbdistillery - save 25% off your entire purchase. Visit CBDistillery.com and use promo code MESSY Calm - Calm has an exclusive offer just for listeners of our show– get 40% off a Calm Premium Subscription at calm.com/messy.

Transcribed - Published: 14 October 2025

It’s Okay to Be Yourself with Baylen Dupree

This week Christina and Jamie are joined by Baylen Dupree. She opens up about having Tourette syndrome, the importance of being yourself, why it's crucial to remember that everyone is struggling, and more. Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch Baylen's Beautifully Complex: https://beautifullycomplexbybaylen.com/ This episode is sponsored by: Fatty15 - Fatty15 is on a mission to optimize your C15 levels to help support your long-term health and wellness -Get an additional 15% off their 90-day subscription Starter Kit at fatty15.com/MESSY and using code MESSY at checkout. OPositiv - Take proactive care of your health and head to OPositiv.com/MESSY or enter MESSY at checkout for 25% off your first purchase.  Wild Grain - For a limited time, Wildgrain is offering our listeners $30 off the first box - PLUS free Croissants in every box - when you go to Wildgrain.com/MESSY to start your subscription. Magic Spoon - Get 5 dollars off your next order at MagicSpoon.com/MESSY. Or look for Magic Spoon on Amazon or in your nearest grocery store. Jones Road - Use code MESSY at jonesroadbeauty.com to get a Free Gift with Purchase! #JonesRoadBeauty #ad

Transcribed - Published: 7 October 2025

Megan Mullally

This week Christina and Jamie are joined by Megan Mullally. They discuss how her role as Karen on Will & Grace came to be, understanding family trauma, the comfort of TV, and more. Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This episode is sponsored by: Calm - Calm has an exclusive offer just for listeners of our show– get 40% off a Calm Premium Subscription at calm.com/messy. This is an amazing value. CBDistillery - If you’re ready for better sleep, less stress and feeling good in your own skin again, try CBD from C B Distillery. Save 25% off your entire purchase. Visit cbdistillery.com and use promo code MESSY

Transcribed - Published: 30 September 2025

Do What You Can When You Can

This week Christina and Jamie are joined by Christina’s friend, Cindy Locke. They share how they first connected online and discuss the impact of trauma, advice to people who are newly diagnosed, the importance of support, and more. Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This episode is sponsored by: CBDistillery - If you’re ready for better sleep, less stress and feeling good in your own skin again, try CBD from C B Distillery. Save 25% off your entire purchase. Visit cbdistillery.com and use promo code MESSY OPositiv - Take proactive care of your health and head to OPositiv.com/MESSY or enter MESSY at checkout for 25% off your first purchase.  ZocDoc - Stop putting off those doctors appointments and go to Zocdoc.com/MESSY to find and instantly book a top-rated doctor today.  AG 1 - If you’re ready to turn down the stress, and focus on the rest, head to drinkag1.com/MESSY to get a FREE Frother with your first purchase of AGZ.  iRestore - Unlock your best skin with @iRestorelaser and HUGE savings on the iRestore Illumina Face Mask with code MESSY at irestore.com/messy  #irestorepod

Transcribed - Published: 23 September 2025

Fraser Olender

This week, Christina and Jamie are joined by Fraser Olender from “Below Deck.” They discuss what his job as chief stew actually entails, his journey to find his true self, the escape of being busy, and much more. Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This episode is sponsored by: MudWtr -Start your new morning ritual & get up to 43% off your @MUDWTR with code [MESSY] at  mudwtr.com/messy #mudwtrpod Jones Road - Use code MESSY at jonesroadbeauty.com to get a Free Gift with Purchase! #JonesRoadBeauty #ad Calm - Calm has an exclusive offer just for listeners of our show– get 40% off a Calm Premium Subscription at calm.com/messy. This is an amazing value.

Transcribed - Published: 16 September 2025

We Are Not the Things That Happen to Us

This week, Christina and Jamie read listener emails and discuss conditional friends, not identifying as the things that happen to us, staying honest, and more. Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This episode is sponsored by: Fatty15 - Fatty15 is on a mission to optimize your C15 levels to help support your long-term health and wellness -Get an additional 15% off their 90-day subscription Starter Kit at fatty15.com/MESSY and using code MESSY at checkout. Everyplate - Dig into these flavor-packed meals your household will love. New customers can enjoy this special offer of only $1.99 a meal. Go to everyplate.com/podcast and use code MESSY199 to get started O-Positiv - Take proactive care of your health and head to OPositiv.com/MESSY or enter MESSY at checkout for 25% off your first purchase.  Magic Spoon - Get 5 dollars off your next order at MagicSpoon.com/MESSY. Or look for Magic Spoon on Amazon or in your nearest grocery store.

Transcribed - Published: 9 September 2025

Change Your Brain, Change Your Pain with Dr. Daniel Amen

This week, Christina and Jamie are joined by Dr. Daniel Amen, a physician, double board-certified psychiatrist, and award-winning researcher. They discuss why pain can also live in your brain, the doom loop and how to get out of it, the cost of repressed emotions, and more. Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This episode is sponsored by: Hexclad - Find your forever cookware @hexclad and get 10% off at hexclad.com/messy #hexcladpartnerHoneylove: Save 20% Off Honeylove by going to honeylove.com/messy #honeylovepod AGZ - Start taking your sleep seriously with AGZ. Head to drinkag1.com/messy to get a FREE welcome kit with the flavor of your choice that includes a 30 day supply of AGZ and a free frother Calm - Calm has an exclusive offer just for listeners of our show– get 40% off a Calm Premium Subscription at calm.com/messy. This is an amazing value.

Transcribed - Published: 2 September 2025

We Have to Pivot

This week, Christina and Jamie read listener emails and discuss their kids starting the new school year, the power of manifestation, accepting reality, and much more. Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This episode is sponsored by: Calm - Calm has an exclusive offer just for listeners of our show– get 40% off a Calm Premium Subscription at calm.com/messy. This is an amazing value. O-Positiv - Take proactive care of your health and head to OPositiv.com/MESSY or enter MESSY at checkout for 25% off your first purchase.  Sleep Number - It’s the Sleep Number's Biggest Sale of the Year.    25% Off the i8 Bed plus free home delivery.  Limited time. Exclusively at a Sleep Number® store near you.  See store or sleepnumber.com for details. Lola - Get 35% off your entire order at Lolablankets.com by using code Messy at checkout. Experience the world’s #1 blanket with Lola Blankets.

Transcribed - Published: 26 August 2025

I Just Wanna Be Stoned

This week, Christina and Jamie read listener emails and discuss hormones, housewives, acknowledging the struggle, and more. Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This episode is sponsored by: Sleep Number - It’s the Sleep Number's Biggest Sale of the Year.    25% Off the i8 Bed plus free home delivery.  Limited time. Exclusively at a Sleep Number® store near you.  See store or sleepnumber.com for details. MudWtr - Start your new morning ritual & get up to 43% off your @MUDWTR with code MESSY at  mudwtr.com/messy! #mudwtrpod iRestore - Unlock your best hair & skin with @iRestorelaser and HUGE savings on the iRESTORE Elite + Illumina Face Mask Bundle with code Messy25 at irestore.com/messy25#irestorepod ZocDoc - Stop putting off those doctors appointments and go to Zocdoc.com/MESSY to find and instantly book a top-rated doctor today.  Everyplate - Dig into these flavor-packed meals your household will love. New customers can enjoy this special offer of only $1.99 a meal. Go to everyplate.com/podcast and use code MESSY199 to get started. Applied as discount on first box, limited time only.

Transcribed - Published: 19 August 2025

Ed Helms

This week, Christina and Jamie are joined by Ed Helms. They discuss working together on "Vacation," his love of comedy, the importance of curiosity, and much more. Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This episode is sponsored by: Lola - Get 35% off your entire order at Lolablankets.com by using code Messy at checkout. Experience the world’s #1 blanket with Lola Blankets. Magic Spoon - Get 5 dollars off your next order at MagicSpoon.com/MESSY. Or look for Magic Spoon on Amazon or in your nearest grocery store. Fatty15 - Fatty15 is on a mission to optimize your C15 levels to help support your long-term health and wellness -Get an additional 15% off their 90-day subscription Starter Kit at fatty15.com/MESSY and using code MESSY at checkout.Sleep Number - It’s the Sleep Number's Biggest Sale of the Year.    25% Off the i8 Bed plus free home delivery.  Limited time. Exclusively at a Sleep Number® store near you.  See store or sleepnumber.com for details. Calm - Calm has an exclusive offer just for listeners of our show– get 40% off a Calm Premium Subscription at calm.com/messy.

Transcribed - Published: 12 August 2025

Live From the Hospital

This week, Christina joins Jamie live from the hospital in LA. They discuss what Christina’s going through, her recent trip abroad, their upcoming memoirs, the way the universe works, and much more. Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This episode is sponsored by: IRestore - Unlock your best hair & skin with @iRestorelaser and HUGE savings on the iRESTORE Elite + Illumina Face Mask Bundle with code MESSY25 at irestore.com/messy25 #irestorepod O-Positiv - Take proactive care of your health and head to OPositiv.com/MESSY or enter MESSY at checkout for 25% off your first purchase.  GoPure - Get 25% Off @goPure with code Messy at https://www.gopurebeauty.com/messy  #goPurepod Honeylove - Save 20% Off Honeylove by going to honeylove.com/messy #honeylovepod Sleep Number- It’s the Sleep Number's Biggest Sale of the Year.    25% Off the i8 Bed plus free home delivery.  Limited time. Exclusively at a Sleep Number® store near you.  See store or sleepnumber.com for details.

Transcribed - Published: 5 August 2025

Jenny Mollen

This week, Christina and Jamie are joined by Jenny Mollen, a New York Times bestselling author and actor. They discuss the feeling of not being in control, the trials of parenting, and more. Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This episode is sponsored by: Honeylove - Save 20% Off Honeylove by going to honeylove.com/messy #honeylovepod Mudwtr - Start your new morning ritual & get up to 43% off your @MUDWTR with code Messy at  mudwtr.com/messy! #mudwtrpod Everyplate - Dig into these flavor-packed meals your household will love. New customers can enjoy this special offer of only $1.99 a meal. Go to everyplate.com/podcast and use code Messy199 to get started. Applied as discount on first box, limited time only.

Transcribed - Published: 29 July 2025

Easy on My Nervous System

This week, Christina and Jamie read listener emails and discuss wins and losses, shows that are easy on the nervous system, why people don't understand invisible diseases, and much more. Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This episode is sponsored by: O-Positiv - Take proactive care of your health and head to OPositiv.com/MESSY or enter MESSY at checkout for 25% off your first purchase.  Everyplate - Dig into these flavor-packed meals your household will love. New customers can enjoy this special offer of only $1.99 a meal. Go to everyplate.com/podcast and use code Messy199 to get started. Applied as discount on first box, limited time only. Function - Function currently has a waitlist, but they are offering my audience the chance to skip it! Head to functionhealth.com/MESSY or enter code MESSY when signing up to skip the waitlist!

Transcribed - Published: 22 July 2025

Any Movement Counts with Doctor Gretchen

This week, Christina and Jamie are joined by Dr. Gretchen Hawley, an MS-certified specialist and physical therapist. They discuss what to do if you're feeling overwhelmed, the importance of staying consistent, why mindset is just as important as movement, and more. Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch Get the latest research from Doctor Gretchen here: https://www.doctorgretchenhawley.com/offers/MTbWv7kN?coupon_code=MESSY30  This episode is sponsored by: Mudwtr - Start your new morning ritual & get up to 43% off your @MUDWTR with code Messy at  mudwtr.com/messy! #mudwtrpod Beam is offering UP TO 40% off their best-selling Dream Powder for our listeners.  Go to shopbeam.com/MESSY and use code MESSY at checkout.  Zoc Doc - Stop putting off those doctors appointments and go to Zocdoc.com/MESSY to find and instantly book a top-rated doctor today. Beam

Transcribed - Published: 15 July 2025

Life Is Like an Episode of Chopped

This week, Christina and Jamie read listener emails and discuss body work, Christina’s new obsession, and much more. Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This episode is sponsored by: Fatty15 - Fatty15 is on a mission to optimize your C15 levels to help support your long-term health and wellness -Get an additional 15% off their 90-day subscription Starter Kit at fatty15.com/MESSY and using code MESSY at checkout. Mudwtr - Start your new morning ritual & get up to 43% off your @MUDWTR with code Messy at  mudwtr.com/messy! #mudwtrpod HoneyLove - Save 20% Off Honeylove by going to honeylove.com/messy ! #honeylovepod

Transcribed - Published: 8 July 2025

Clea Shearer

This week, Christina and Jamie are joined by Clea Shearer. They discuss how The Home Edit came to be, Clea’s breast cancer diagnosis, and the importance of fighting for your health and trusting your gut. Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This episode is sponsored by: Function - Function currently has a waitlist, but they are offering my audience the chance to skip it! Head to functionhealth.com/MESSY or enter code MESSY when signing up to skip the waitlist! GoPure - Get 25% Off @goPure with code Messy  at https://www.gopurebeauty.com/messy #goPurepod O-Positiv - Take proactive care of your health and head to OPositiv.com/MESSY or enter MESSY at checkout for 25% off your first purchase.  Ag1 - Head to drinkag1.com/messy to subscribe for less than $3 a day. and you get a free welcome kit with a shaker bottle, 5 AG1 travel packs and more with your first purchase.

Transcribed - Published: 1 July 2025

There Are All Kinds of Heartbreak

This week, Christina and Jamie read listener emails and discuss how connected our bodies are with our emotions, friendship heartbreaks, starting a family, and more. Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This episode is sponsored by: Beam - Right now, Beam is offering UP TO 40% off their best-selling Dream Powder for our listeners. Perfect timing to lock in your summer sleep strategy. Go to shopbeam.com/MESSY and use code MESSY at checkout.  Sleep Number - It’s the Sleep Number 4th of July Sale.  Save over $600 on the Sleep Number p5 king smart bed, the lowest price of the season.  Limited time. Exclusively at a Sleep Number® store near you.  See store or sleepnumber.com for details. Function - Function currently has a waitlist, but they are offering my audience the chance to skip it! Head to functionhealth.com/MESSY or enter code MESSY when signing up to skip the waitlist!”  iRestore - Unlock your best skin with @iRestorelaser and HUGE savings on the iRestore Illumina Face Mask with code MESSY25 at irestore.com/messy25! #irestorepod Calm - Calm has an exclusive offer just for listeners of our show– get 40% off a Calm Premium Subscription at calm.com/MESSY. This is an amazing value and you get unlimited access to Calm’s entire library

Transcribed - Published: 24 June 2025

Judd Apatow

This week, Christina and Jamie are joined by Judd Apatow. They discuss working on "Anchorman," parenting advice, spirituality, and much more.  Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This episode is sponsored by: Zoc Doc - Stop putting off those doctors appointments and go to Zocdoc.com/MESSY to find and instantly book a top-rated doctor today.  Magic Spoon - Get 5 dollars off your next order at MagicSpoon.com/MESSY. Or look for Magic Spoon on Amazon or in your nearest grocery store.  Beekeeper's Naturals - Beekeeper’s Naturals is offering you an exclusive offer: Go to beekeepersnaturals.com/MESSY or enter code MESSY to get 20% off your order Mudwtr - Start your new morning ritual & get up to 43% off your @MUDWTR with code MESSY at  mudwtr.com/messy! #mudwtrpod Sleep Number - It’s the Sleep Number 4th of July Sale.  Save over $600 on the Sleep Number p5 king smart bed, the lowest price of the season.  Limited time. Exclusively at a Sleep Number® store near you.  See store or sleepnumber.com for details.

Transcribed - Published: 17 June 2025

How Could You Not Like Pizza?

This week, Christina and Jamie read listener emails and discuss New York pizza, the trick to finding lost jewelry, how brain inflammation affects us, and more. Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This episode is sponsored by: Fatty15 - Fatty15 is on a mission to optimize your C15 levels to help support your long-term health and wellness -Get an additional 15% off their 90-day subscription Starter Kit at fatty15.com/MESSY and using code MESSY at checkout. Honeylove- Save 20% Off Honeylove by going to honeylove.com/messy  #honeylovepod OPositiv - Take proactive care of your health and head to OPositiv.com/MESSY or enter MESSY at checkout for 25% off your first purchase.  Function - Function currently has a waitlist, but they are offering my audience the chance to skip it! Head to functionhealth.com/MESSY or enter code MESSY when signing up to skip the waitlist!” Calm - Calm has an exclusive offer just for listeners of our show– get 40% off a Calm Premium Subscription at calm.com/MESSY. This is an amazing value and you get unlimited access to Calm’s entire library

Transcribed - Published: 10 June 2025

Kaitlyn Bristowe

This week, Christina and Jamie are joined by Kaitlyn Bristowe. They discuss starting over, the impact of therapy, their love of dance, and much more.  Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This episode is sponsored by: BetterHelp - This episode is sponsored by/brought to you by BetterHelp. Give online therapy a try at betterhelp.com/messy and get on your way to being your best self. Magic Spoon - Get 5 dollars off your next order at MagicSpoon.com/MESSY. Or look for Magic Spoon on Amazon or in your nearest grocery store.  Go Pure - Get 25% OFF @goPure with code MESSY at https://gopurebeauty.com/MESSY! #goPurepod

Transcribed - Published: 3 June 2025

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