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MeSsy with Christina Applegate & Jamie Lynn Sigler

Do What You Can When You Can

MeSsy with Christina Applegate & Jamie Lynn Sigler

Wishbone Production

Personal Journals, Health & Fitness, Society & Culture

4.93.7K Ratings

🗓️ 23 September 2025

⏱️ 52 minutes

🧾️ Download transcript

Summary

This week Christina and Jamie are joined by Christina’s friend, Cindy Locke. They share how they first connected online and discuss the impact of trauma, advice to people who are newly diagnosed, the importance of support, and more. Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This episode is sponsored by: CBDistillery - If you’re ready for better sleep, less stress and feeling good in your own skin again, try CBD from C B Distillery. Save 25% off your entire purchase. Visit cbdistillery.com and use promo code MESSY OPositiv - Take proactive care of your health and head to OPositiv.com/MESSY or enter MESSY at checkout for 25% off your first purchase.  ZocDoc - Stop putting off those doctors appointments and go to Zocdoc.com/MESSY to find and instantly book a top-rated doctor today.  AG 1 - If you’re ready to turn down the stress, and focus on the rest, head to drinkag1.com/MESSY to get a FREE Frother with your first purchase of AGZ.  iRestore - Unlock your best skin with @iRestorelaser and HUGE savings on the iRestore Illumina Face Mask with code MESSY at irestore.com/messy  #irestorepod

Transcript

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0:00.0

Hi, I'm Christina Applegate.

0:02.6

And I'm Jamie Lynn Sigler.

0:04.2

And this is messy.

0:10.6

The following message is brought to you by Novartis.

0:18.1

Hi, I'm Jamie Lynn Sigler.

0:19.8

When it comes to relapsing MS treatments, your choice

0:22.5

matters. That's why talking to your doctor about your options is a big deal. But how do you know

0:27.1

what to ask? Figuring that out can be daunting. That's why I partner with Novartis to create an

0:32.8

MS treatment decision guide. It's packed with helpful info and questions for your doctor to help make an

0:38.1

informed decision. Trust me, the more prepared you are, the more confident you'll feel. Download the

0:43.5

guide right to your phone, only at treatmentdecisionguide.com.

0:52.5

Hi, little peoples and bigger peoples.

0:57.8

It's Christina.

0:59.1

And Jamie.

1:00.6

And today we have a guest that, oh, see, the waterworks are going.

1:06.9

In 2021 of July, I posted that I had MS because I had to because there were pictures

1:15.8

circulating around with me in a wheelchair. And so I got ahead of it. And I normally do not

1:24.3

look at comments. But there was one comment that really stayed with me.

1:34.3

And what we've come to realize, Jamie, we know this, that community understanding, when we

1:42.4

read our listeners' emails, is that you've got to find a person that

1:48.2

fucking gets you because nobody else fucking gets you hence why they judge you and all this other

1:53.9

shit anyway my point being there was a comment from a woman named Cindy, and I wrote her back.

...

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