49ers Talk: A San Francisco 49ers Podcast

“49ers Talk” hosts Matt Maiocco and Jennifer Lee Chan preview San Francisco’s playoff matchup against the Seattle Seahawks. Matt also speaks with Greg Papa to break down key matchups for the pivotal NFC Divisional Round clash and discuss how playing Seattle Week 18 could be an advantage for San Francisco.

Transcribed - Published: 17 January 2026

When 49ers rookie cornerback Upton Stout was selected in the third round of the 2025 NFL draft, his first phone call with the organization went viral. He showed a charisma and passion in that first interaction that has carried over onto the field. Stout will start at nickel Saturday vs. the Seahawks in the NFC divisional round of the NFL playoffs, a far cry from the hills of Western Kentucky where he started making a name for himself. On this episode of "49ers Talk," Matt Maiocco sits down with the determined rookie to reflect on what motivates him to be successful, his biggest adjustment since becoming a professional and what a return of Fred Warner would mean to this team and special season. Matt also joins co-host Jennifer Lee Chan to discuss the news that Fred Warner was officially ruled out for Saturday's playoff game, as well as injury updates on WR Ricky Pearsall's status and other limited players. The duo discuss the impact Warner's presence at practice has had on the team this week, and how Seahawks QB (and former 49ers backup) Sam Darnold's lack of success in big games will follow him throughout his career unless he can turn it around; an apparent oblique injury won't help that cause.

Transcribed - Published: 16 January 2026

Two bitter rivals will play each other for a third time this season when the 49ers and Seahawks clash on Saturday at Lumen Field in the NFC divisional round. With the season series split at one win apiece, its anyone's game to impose their will. On this episode of "49ers Talk," co-hosts Matt Maiocco and Jennifer Lee Chan discuss the storylines surrounding this storied rivalry and what San Francisco must do to compete with such a formidable opponent in Seattle. The duo details what linebacker Fred Warner's return to practice means to the team, and provides injury updates with a close eye on receiver Ricky Pearsall, who also returned in limited fashion. Matt then sits down with Jauan Jennings' high school coach, Philip Shadowens, to learn what makes the wideout such a unique and enigmatic talent that has endeared himself to the 49ers Faithful.

Transcribed - Published: 15 January 2026

The 49ers' magical opening touchdown drive Sunday at Lincoln Financial Field gave them an early lead, but the Eagles wore down San Francisco's already depleted defense and George Kittle tore his Achilles after that. Undeterred, the 49ers mounted an incredible fourth-quarter comeback that defied the odds and secured them a divisional-round matchup against the rival Seahawks. On this episode of "49ers Talk," co-hosts Matt Maiocco and Jennifer Lee Chan break down the wild-card performance from a very unlikely bunch of 49ers players, who gutted out a remarkable result in a hostile environment. The duo highlights the 49ers' season-long resiliency, especially in big moments, and address how Brock Purdy turned an otherwise forgettable performance around with his leadership and determination. Matt and Jennifer also discuss how the coaching staff has steered the ship as unsung contributors popped up throughout the season.

Transcribed - Published: 12 January 2026

“49ers Talk” hosts Matt Maiocco and Jennifer Lee Chan provide the latest injury updates and look ahead to San Francisco’s matchup against the Philadelphia Eagles in this week’s NFL Wild Card round before Matt joins Greg Papa to discuss the challenges facing a stacked Eagles’ offense and share which Niners players could make a difference this Sunday.

Transcribed - Published: 10 January 2026

Veteran 49ers fullback Kyle Juszczyk has played a lot of football, and he views Sunday's NFC Wild Card Game against the Philadelphia Eagles as just another opportunity for San Francisco to defy the odds. While the Eagles are favored for many reasons, there's an underlying sentiment that this matchup might be closer than what it appears. On this episode of "49ers Talk," co-host Matt Maiocco and Jennifer Lee Chan discuss how San Francisco can expose some of Philadelphia's deficiencies in what many believe has been an underachieving Eagles team this season. Matt and Jennifer also provide important health updates on Trent Williams and Ricky Pearsall, who will be crucial on Sunday for the 49ers. Then, Matt sits down with Juszczyk to break down how the 49ers can beat the Eagles. They also touch on the secrets to Juszczyk's longevity in the league and how he has been able to compete at such a high level for so long.

Transcribed - Published: 9 January 2026

The San Francisco 49ers and Philadelphia Eagles renew their fiery rivalry on Sunday, and the storylines center around which Eagles offense will show up in the playoffs, can Brock Purdy recapture the form that carried San Francisco into the postseason, and will the 49ers' depleted defense band together in time for an afternoon kickoff in Philadelphia? "49ers Talk" host Matt Maiocco is joined by NBC Sports Philadelphia's 'Eagle Eye,' hosts Dave Zangaro and Reuben Frank for a discussion about what will shape-up as a fiercely contested NFC wild-card clash. The trio talk 49ers-Eagles rivaled history, injury reports, pessimism emanating from both camps and make predictions.

Transcribed - Published: 8 January 2026

The NFL's Wild Card Weekend was set Sunday after the conclusion of Week 18, pitting the 49ers against familiar foes in the Eagles with an enticing opening-round matchup. On this episode of "49ers Talk," co-hosts Matt Maiocco and Jennifer Lee Chan discuss the storylines surrounding this playoff contest, from the hostile environment in Philly to their load-management approach to the postseason, and Brock Purdy's season-ending injury in the 2023 NFC Championship Game. Will the 49ers' Week 18 loss to the Seahawks serve as their wake-up call? And, can they get healthy enough in time to step up to that challenge with an eye on redemption against the Eagles?

Transcribed - Published: 5 January 2026

The highly anticipated winner-take-all Week 18 between the 49ers and Seahawks didn't quite live up to the hype. Seattle's defense stifled San Francisco's offense, as the Seahawks pulled out a 13-3 win to secure the NFC West title and the conference's No. 1 seed, while the 49ers now have a more difficult postseason path on the road. On this episode of "49ers Talk," co-hosts Matt Maiocco and Jennifer Lee Chan discuss how the Seahawks thoroughly outplayed the 49ers from their potent rushing attack to their unrelenting pressure on the defensive line. Matt and Jennifer also discuss some silver-linings as the 49ers hit the road for the NFL playoffs and how some scenarios are more favorable than others.

Transcribed - Published: 4 January 2026

“49ers Talk” hosts Matt Maiocco and Jennifer Lee Chan discuss San Francisco’s rivalry with the Seahawks and provide the latest injury updates before Matt speaks with general manager John Lynch on the importance of the team's Week 18 game. Also, offensive lineman Colton McKivitz joins Matt to share why home field advantage is so important in the postseason.

Transcribed - Published: 2 January 2026

With a number of limited or nonparticipants in the 49ers' first practice of the week, depth players once again will need to step up and fill their role. What's also familiar is San Francisco's opponent in the regular-season finale on Saturday at Levi's Stadium: Sam Darnold and the Seattle Seahawks. On this episode of "49ers Talk," co-hosts Matt Maiocco and Jennifer Lee Chan discuss how clutch San Francisco's depth has been this season, especially in prime-time games. Also, they detail the many playoff permutations that will swirl following Week 18's results, along with just how much defensive coordinator Robert Saleh trusts his players and if Deommodore Lenoir will get a chance to shadow one of the league's best receivers Saturday in Jaxon Smith-Njigba.

Transcribed - Published: 31 December 2025

On this episode of "49ers Talk," co-hosts Matt Maiocco and Jennifer Lee Chan discuss the electric atmosphere at Levi's Stadium on Sunday and how San Francisco has proven all season that this iteration of the team is built for prime-time games. Also, the duo discusses how good of a job coach Kyle Shanahan and 49ers GM John Lynch have done keeping the team's competitive window open, as well as how a unique roster and season is capturing the hearts of the 49ers Faithful.

Transcribed - Published: 29 December 2025

“49ers Talk” host Matt Maiocco provides the latest injury updates before speaking with general manager John Lynch about San Francisco's Week 17 matchup vs. the Chicago Bears. Also, NBC Sports' Cris Collinsworth joins Matt to discuss how Kyle Shanahan has done one of the best coaching efforts he's ever seen.

Transcribed - Published: 27 December 2025

“49ers Talk” hosts Matt Maiocco and Jennifer Lee Chan preview San Francisco's Week 17 matchup against the Chicago Bears and discuss this week’s Pro Bowl selections before JLC is joined by "Sunday Night Football in America" host and former NFL head coach Tony Dungy to break down key matchups in 49ers-Bears and reflect on the Niners' improbable run to the playoffs this season.

Transcribed - Published: 25 December 2025

On this episode of "49ers Talk," co-hosts Matt Maiocco and Jennifer Lee Chan break down the statement San Francisco made against the Colts in prime-time. Also, as the league results aligned in Week 16 in the 49ers' favor, Matt and Jennifer discuss how difficult the final two regular season games against the NFC's top two teams will be. The 49ers will attempt to rally behind their high-octane offense and ride the momentum to the No.1 seed.

Transcribed - Published: 23 December 2025

“49ers Talk” host Matt Maiocco provides the latest injury updates before speaking with coach Kyle Shanahan about San Francisco's Week 16 matchup vs. the Indianapolis Colts. Also, Greg Papa joins Matt to discuss how the Los Angeles Rams’ Week 16 loss to the Seattle Seahawks opens the door for the 49ers to capture the NFC West and the NFC's No.1 playoff seed.

Transcribed - Published: 21 December 2025

On this episode of "49ers Talk," co-hosts Matt Maiocco and Jennifer Lee Chan break down the Seattle Seahawks' shocking overtime victory against the Los Angeles Rams and how it affects the NFC playoff picture. Did the Rams have an early blueprint to stop the Seahawks they let slip away? And which area must the 49ers improve the most if they expect to contend for a now wide-open No. 1 seed? Matt and Jennifer also discuss the 49ers' looming matchup vs. Philip Rivers and the Indianapolis Colts on "Monday Night Football," and how close Rivers was to actually suiting up for San Francisco back in 2022.

Transcribed - Published: 19 December 2025

It wasn't a picture-perfect performance Sunday vs. the Titans, but the 49ers returned from their bye week energized and executed when they needed to on their way to 37-24 victory at Levi's Stadium. Offensively, they looked sharp and scored on their first five possessions. Quarterback Brock Purdy threw for three touchdowns and zero interceptions as Ricky Pearsall finally broke through with a team-high 96 receiving yards and Jauan Jennings added two touchdowns. San Francisco's defense was tested, however, and will need to promptly turn things around with three regular-season games left and a ton on the line. On this episode of "49ers Talk," co-hosts Matt Maiocco and Jennifer Lee Chan discuss how San Francisco's offense is jelling at the right time, and how Purdy's confidence is contagious to the whole position group. They also detail how the 49ers' defense will need to step up amid a heated playoff race within their conference and, most importantly, their own division. San Francisco's postseason future is right in front of them, and they will play a large role in how it plays out down the stretch.

Transcribed - Published: 15 December 2025

Kyle Shanahan joins "49ers Talk" co-host Matt Maiocco to discuss the challenges and benefits a late bye week presents San Francisco down the final stretch of the season. Matt asks Kyle how QB Brock Purdy can finish the season strong, evaluates wideout Ricky Pearsall's usage, and how the idea of meaningful December football can motivate his team. Greg Papa also joins Matt on this episode to break down how a young Tennessee Titans team with little to lose can present a dangerous obstacle for the 49ers. Papa points out where the 49ers need to fortify their resources on defense and if this is the game Pearsall can return to his early-season production

Transcribed - Published: 13 December 2025

Hall of Fame linebacker Patrick Willis, now an Alumni Ambassador for San Francisco after spending his entire career in the Bay, joins "49ers Talk" co-host Matt Maiocco to discuss the impact Super Bowl LX can have on the region and how its immersive, family-friendly festivities can be enjoyed by all who attend -- whether they have a ticket or not. Patrick and Matt also tackle the 49ers' surprising run this season and how overcoming adversity has been a hallmark of their success. Willis expands on what San Francisco needs to focus on in its final four games, as well as how his relationship with the organization affords him the opportunity to connect with upcoming great 49ers players. Jennifer Lee Chan also joins Matt to paint the NFC playoff picture, review roster changes and injury updates, plus detail San Francisco's final stretch.

Transcribed - Published: 11 December 2025

The 49ers enjoyed a bump in their playoff position without lifting a finger in their bye week, the last of the NFL season. The other teams battled it out in a blockbuster of matchups with gargantuan postseason implications across the board in both NFL conferences. In the NFC, the Green Bay Packers leapfrogged the Chicago Bears to take the No. 2 overall seed while dropping their division rivals to the seventh and final wild-card position, a precipitous fall for an opponent in one afternoon of work. The 49ers will play those Bears in a Sunday night clash in Week 17, which surely will intrigue. But, first come the Tennessee Titans in a matinee next Sunday, a potent opponent with nothing to lose. On this episode of "49ers Talk," co-hosts Matt Maiocco and Jennifer Lee Chan look ahead to San Francisco's final four games, a stretch that will test it in all phases and could define the rest of the team's entire season.

Transcribed - Published: 8 December 2025

President of Football Operations/General Manager John Lynch joins '49ers Talk,' co-host Matt Maiocco for an update on the organization before San Francisco starts its final stretch of the 2025 NFL season. Lynch detailed the pride he has for the 49ers enduring tremendous adversity to place themselves squarely in the NFC playoff race before offering his expectations for the rest of the season. Jennifer Lee Chan also joins Maiocco to break down the 49ers' chances of making a deep playoff run as San Francisco begins to hit its stride.

Transcribed - Published: 6 December 2025

Its Week 14 in the NFL, and the 49ers finally have reached their bye. As San Francisco players rest and recuperate, "49ers Talk" co-hosts Matt Maiocco and Jennifer Lee Chan take a pulse on the 49ers' season with just four regular-season games left. Jennifer, Matt, and later Greg Papa, discuss if Kyle Shanahan's current coaching staff is his best yet, and if that makes him a strong candidate for his first NFL Coach of the Year award. They also detail the 49ers' latest injuries and roster additions, then discuss if Christian McCaffrey's public support of Roger Craig can convince the Pro Football Hall of Fame committee to induct the legendary 49ers running back.

Transcribed - Published: 3 December 2025

The 49ers, on Sunday, notched their first three-game winning streak since the opening three weeks of the season and won in Cleveland for the first time since Nov. 1984. The 49ers' latest win was exhibition in execution from the kickoff as they played complimentary football in all three phases. Brock Purdy played errorless football with excellent decision-making, while extending plays when needed. The special teams group bolstered the 49ers' field-position on returns and made timely kicks when needed, while the defense has been humming the last few weeks, creating turnovers and finally adding an element of pressure from the D-line that spurred San Francisco to victory. On this episode of '49ers Talk,' co-hosts Matt Maiocco and Jennifer Lee Chan break down San Francisco's decisive 26-8 road win over the Cleveland Browns at Huntington Bank Field. From Brock Purdy's bounce-back performance following a mistake-filled game, to special teams and defensive units flourishing, to a coach committed to his preparation and scheme in what might be his best coaching season for the Faithful, Matt and Jennifer detail a team finding health and success in time for a much-needed break during their Week 14 bye week.

Transcribed - Published: 1 December 2025

San Francisco's president of football operations John Lynch sat down with “49ers Talk” host Matt Maiocco this week to preview their Week 13 matchup vs. the Cleveland Browns and provide organizational news and updates. Maiocco and Lynch also discuss how Brock Purdy can bounce back in Week 13 following a poor display against the Carolina Panthers, Brandon Aiyuk's current relationship with the organization in light of his contract situation, and how San Francisco's special teams group has turned from a liability last season into a weapon this year. Finally, Maiocco provides injury updates that will affect the 49ers' defense Sunday and names the five key San Francisco players to watch in Week 13.

Transcribed - Published: 29 November 2025

The 49ers are entrenched in the final NFC playoff spot as they prepare to face the Cleveland Browns. However, with low temperatures, high-winds, and possible perception forecast for Sunday's matchup, holding onto that precious wild card spot might be more complicated. Having lost their previous contest in Cleveland under similar conditions in 2023, San Francisco will be tasked with executing their offense more efficiently this time while mitigating current NFL sack leader Myles Garrett. On this episode of "49ers Talk," co-hosts Matt Maiocco and Jennifer Lee Chan discuss Brock Purdy's regression last week against the Panthers and how he and the 49ers' offense can minimize mistakes against familiar obstacles in inclement weather and a formidable pass-rush. Also, Matt and Jennifer provide injury updates, surprising takes on a San Francisco offensive line playing well under-the-radar and where the 49ers might look in the draft. They also praise the evolution of Christian McCaffrey's game during an incredible individual season.

Transcribed - Published: 27 November 2025

The 49ers entered Monday night knowing the needed a win to distance themselves from another NFC playoff contender in the Carolina Panthers. Despite three uncharacteristic interceptions from quarterback Brock Purdy, the 49ers' defense stepped up to secure a 20-9 victory as safety Ji'Ayir Brown's two interceptions helped San Francisco hold Carolina to single digits. On this episode of "49ers Talk," co-hosts Matt Maiocco and Jennifer Lee Chan discuss Purdy's dip in form and whether he's physically 100 percent, linebacker Curtis Robinson's long-awaited first NFL start and Brown's career night. Finally, wide receiver Brandon Aiyuk's curious contract situation is highlighted: With five regular-season games remaining, will he return? And what are the motivating factors for both parties if he does?

Transcribed - Published: 25 November 2025

“49ers Talk” host Matt Maiocco discusses the latest news on Brandon Aiyuk before speaking with coach Kyle Shanahan about San Francisco's Week 12 matchup vs. the Carolina Panthers on Monday night. Also, Greg Papa joins Matt to discuss Brock Purdy’s performance against the Arizona Cardinals in Week 11 and reflect on the trade that brought Christian McCaffrey to the 49ers.

Transcribed - Published: 22 November 2025

On this episode of "49ers Talk," co-hosts Matt Maiocco and Jennifer Lee Chan reflect on the blockbuster trade that brought Christian McCaffrey to San Francisco ahead of Monday night's matchup against his former team. Additionally, Matt and Jennifer discuss how a healthy 49ers offense will improve their run game. Matt then sits down with defensive back Deommodore Lenoir to discuss his growth as a leader and team captain of the 49ers’ defense.

Transcribed - Published: 21 November 2025

Brock Purdy's return sparked the 49ers' offense, it also brought a much needed divisional win in a blowout against the Cardinals. Purdy threw for three touchdowns on Sunday, two of which went to a favorite target in tight end George Kittle and the other went to offensive fulcrum Christian McCaffrey, who leads the NFL in scrimmage yards this season through Week 11. Skyy Moore set the tone, returning the opening kickoff 98 yards to the 1-yard line, setting up a McCaffrey 1-yard touchdown run. San Francisco maintained control throughout the game, one in which Arizona did itself no favors accumulating a franchise-record 17 penalties. San Francisco did not escape Arizona unscathed though, as kicker Eddy Piñeiro suffered a hamstring injury in the third quarter that could force the team to bring in a new kicker. On this episode of '49ers Talk,' co-hosts Matt Maiocco and Jennifer Lee Chan break down San Francisco's outstanding performance against the Cardinals Sunday at State Farm Stadium. Matt and Jennifer discuss the impact of Purdy's return on the 49ers' offense during a crucial stretch, Kittle and CMC's dominance, and how injuries to both Piñeiro and linebacker Tatum Bethune might affect the team ahead of Monday's showdown with the Carolina Panthers.

Transcribed - Published: 17 November 2025

“49ers Talk” hosts Matt Maiocco and Jennifer Lee Chan provide the latest roster updates before Matt speaks with coach Kyle Shanahan about San Francisco's Week 11 matchup vs. the Arizona Cardinals. Also, Greg Papa joins Matt to discuss Brock Purdy’s return for Sunday’s game and how he could revitalize the Niners for the rest of the season.

Transcribed - Published: 15 November 2025

Brock Purdy returned to practice Wednesday, taking the 49ers' first-team reps at quarterback with a goal of returning in Week 11 against the Arizona Cardinals. Wide receiver Ricky Pearsall, who, like Purdy, has been missing from San Francisco's starting lineup since Week 4, also returned to the practice field. On this episode of "49ers Talk," co-hosts Matt Maiocco and Jennifer Lee Chan discuss how the potential return of two impact players will help the 49ers' offense. Additionally, Matt and Jennifer look ahead to how the 49ers can solidify a playoff spot as they approach a pivotal stretch in their schedule. As far as depth is concerned, Matt and Jennifer debate the balance of player development during a postseason push and how to balance two very important pillars to the season.

Transcribed - Published: 13 November 2025

Matthew Stafford and the Rams' high-powered offense overpowered a 49ers defense reeling from injuries on Sunday, handing San Francisco its first divisional loss with a 42-26 defeat. The 49ers remain locked in the NFC West's third-place spot, fighting for health and positioning as the playoff picture starts to crystallize in the season's second half. On this episode of "49ers Talk," co-hosts Matt Maiocco and Jennifer Lee Chan break down San Francisco's performance against the Rams in Week 10, from an inexperienced defense decimated by injuries to an offense expected to protect such deficiencies despite its own missing pieces. Matt and Jennifer help make sense of how San Francisco can contend moving forward in a highly competitive divisional and conference environment.

Transcribed - Published: 10 November 2025

49ers insider Matt Maiocco provides the latest injury updates before speaking with head coach Kyle Shanahan about San Francisco's Week 10 matchup vs. the Los Angeles Rams. Matt also sits down with tight end George Kittle to discuss how he prepares for game day every week, and his love for cinema. Finally Greg Papa joins Matt to discuss key matchups for Sunday’s game and how it is a must-win for the Niners.

Transcribed - Published: 8 November 2025

The NFL trade deadline came and went Tuesday, and the 49ers stood pat with the roster they have. San Francisco's quiet approach spoke volumes about their intent despite fervor from fans, sticking to their path of growth and development with youth. At 6-3, the 49ers can compete -- and they've decided to do so with the current players at their disposal. On this episode of "49ers Talk," co-hosts Matt Maiocco and Jennifer Lee Chan discuss San Francisco's choice to trust its depth and chemistry over a splashy trade that would mortgage their future. Also, as Brock Purdy and Ricky Pearsall continue rehabbing their injuries, just how close are they to returning? Finally, Matt and Jennifer debate if the 49ers can strike gold again against the Los Angeles Rams after their rivals' Week 5 theatrics.

Transcribed - Published: 6 November 2025

The 49ers bounced back in a big way with a statement win over the New York Giants. San Francisco was laser focused in all three phases, never looking back after taking a second-quarter lead. The 49ers' offense was humming all afternoon, scoring a season-high 34 points while Christian McCaffrey added a pair of touchdowns along with 173 total yards. San Francisco's win didn't come without cost, as 2025 first-round draft pick Mykel Williams went down with a knee injury late in the fourth quarter. On this episode of "49ers Talk," co-hosts Matt Maiocco and Jennifer Lee Chan break down how the 49ers responded to their disappointing loss against the Houston Texans with an offensive outburst in Sunday's win over New York. They also review how Williams' potential loss could affect the 49ers' approach at the NFL trade deadline. Finally, with a pivotal divisional matchup with the Los Angeles Rams looming, Matt and Jennifer discuss Brock Purdy's progress as the quarterback works back from a toe injury.

Transcribed - Published: 3 November 2025

Matt Maiocco speaks with 49ers coach Kyle Shanahan about San Francisco's Week 9 matchup vs. the New York Giants and how he scripts his first 24 offensive plays. Also, Greg Papa joins Matt to assess the 49ers’ season at the halfway point and discuss key matchups for Sunday’s game.

Transcribed - Published: 1 November 2025

In need of reinforcements along their injured defensive line, the 49ers made a trade with the New England Patriots for defensive end Keion White and a 2026 seventh-round draft pick in exchange or a 2026 sixth-rounder. Matt Maiocco and Jennifer Lee Chan discuss how White bolsters a 49ers defensive line whose nine sacks are tied for the second-fewest among all NFL teams this season. Matt also sits down with NBC Sports Boston's Patriots insider Phil Perry to examine White's time with the organization as a former second-round pick of the 2023 NFL Draft. Lastly, Jennifer and Matt review if the 49ers would entertain any other trades, assess rookie Mykel Williams' stock through eight games and provide 49ers injury updates before San Francisco's Week 9 game against the New York Giants at MetLife Stadium.

Transcribed - Published: 30 October 2025

The 49ers came into Week 8 knowing the Texans' defense was elite, but it was Houston's struggling offense that took over Sunday at NRG Stadium. Heavily scrutinized QB C.J. Stroud executed a sound game plan for the Texans, while 49ers teammates George Kittle and Jake Tonges each caught a touchdown on on national Tight Ends Day to keep San Francisco's comeback hopes alive. San Francisco's offense lacked much rhythm beyond that, and the disjointed display effectively ended in a 26-15 loss, their third of the season. On this episode of "49ers Talk," co-hosts Matt Maiocco and Jennifer Lee Chan break down what went wrong with San Francisco on both sides of the ball, which injuries will further affect the 49ers' depleted depth and how they can turn a performance like this around in Week 9 vs. the New York Giants at MetLife Stadium.

Transcribed - Published: 27 October 2025

Matt Maiocco sits down with 49ers coach Kyle Shanahan to discuss the team's upcoming Week 8 matchup vs. DeMeco Ryans' Houston Texans. Also, Greg Bethune, father of San Francisco linebacker Tatum Bethune, joins the show to discuss his son's journey to the NFL

Transcribed - Published: 25 October 2025

Eddy Piñeiro leads the NFL in made field goals without a miss through Week 7, but the 49ers kicker's journey to San Francisco has been anything but perfect. Jennifer Lee Chan sits down with Piñeiro, who shares why he chose to play for the 49ers after Jake Moody's release and how close he came to signing elsewhere. Piñeiro discusses how he brings a jolt to the 49ers' locker room, his fast-growing bond with George Kittle and why football was second to his first love in sport, soccer. Also, Matt Maiocco and Jennifer review the midweek list of 49ers injuries and who might start in Week 8 vs. the Houston Texans.

Transcribed - Published: 23 October 2025

Without their fearless leader, Fred Warner, the 49ers' defense produced a masterclass performance against the red-hot Atlanta Falcons on Sunday while the offense ran all over the field. Matt Maiocco and Jennifer Lee Chan discuss how San Francisco produced one of its most complete performances this season as players stepped up and embraced the challenge of facing a top opponent. With the return of George Kittle and many backups stepping up, the 49ers proved they might have been down, but they sure aren't out.

Transcribed - Published: 20 October 2025

Matt Maiocco speaks with 49ers coach Kyle Shanahan about San Francisco's Week 7 matchup against the Atlanta Falcons, and how losing Fred Warner for the season will impact their young defensive players. Also, Jennifer Lee Chan joins the show for an exclusive interview with NBC Sports NFL broadcaster Cris Collinsworth and analyst Devin McCourty to discuss the loss of Warner, Nick Bosa and more.

Transcribed - Published: 18 October 2025

After a long NFL journey, wide receiver Kendrick Bourne is back with the team who first took a chance on him, and he's beyond grateful for his second 49ers stint. Bourne sits down with '49ers Talk' co-host Matt Maiocco to discuss his path back to San Francisco and how the time away made his return that much sweeter. Bourne details his development over his nine NFL seasons and why he's so happy to be back in the Bay Area. Also, Bourne shares the intricacies of playing wide receiver in Kyle Shanahan's offense and how he values the relationships he has built with fellow teammates like Mac Jones and Ricky Pearsall. Finally, Jennifer Lee Chan and Matt discuss the daunting task of a primetime matchup vs. a surging Atlanta Falcons team and who we could expect to lineup at QB and other key positions in Week 7.

Transcribed - Published: 16 October 2025

The 49ers' health woes continued after San Francisco lost superstar linebacker Fred Warner to a season-ending ankle injury in Sunday's loss to the Tampa Bay Buccaneers. San Francisco responded valiantly, managing to stay competitive throughout the matchup before fading late in the fourth quarter. Baker Mayfield and the Bucs' high-powered offense proved to be too much in the end as the 49ers suffered their second loss of the season. On this episode of '49ers Talk,' co-hosts Matt Maiocco and Jennifer Lee Chan discuss the potential ramifications of Warner's season-ending injury. They then detail Warner's impact on the 49ers organization from ownership to players and how San Francisco will feel his loss both on and off the field. Finally, they deliberate if Warner's injury signifies the beginning of the end in what started out as a promising 49ers' season?

Transcribed - Published: 13 October 2025

Matt Maiocco speaks with 49ers coach Kyle Shanahan about San Francisco's Week 6 matchup vs. the Tampa Bay Buccaneers and how rookie defensive lineman Alfred Collins has made significant strides this season. Also Greg Papa joins Matt to discuss what QB3 Adrian Martinez will bring to 49ers' offense if Mac Jones gets injured on Sunday.

Transcribed - Published: 11 October 2025

Star 49ers running back Christian McCaffrey is off to a hot start offensively this season, showing shades of his 2023 AP Offensive Player of the Year campaign. McCaffrey sits down with Matt Maiocco to discuss a plethora of topics, such as learning route-running from his Super Bowl-winning father, identifying the most valuable asset in professional football and describing how George Kittle helps bring "fun" back into the game. Also, Jennifer Lee Chan stops by to update the 49ers' lengthy injury list and preview the potent Buccaneers offense San Francisco will face in Week 6, led by quarterback Baker Mayfield.

Transcribed - Published: 9 October 2025

Matt Maiocco shares the 49ers’ injury update before sitting down with Greg Papa to recap San Francisco’s thrilling 26-23 overtime win over the Los Angeles Rams on Thursday night at SoFi Stadium and discuss how the victory can set the tone for the rest of the season.

Transcribed - Published: 5 October 2025

An injured 49ers squad defied the odds and dug deep for a 26-23 overtime win over the Los Angeles Rams on Thursday at SoFi Stadium. Backup quarterback Mac Jones delivered his third win in three starts despite laboring through pain all game. Kyle Shanahan managed a very limited and at times inexperienced San Francisco squad, and rookies produced when their numbers were called. Matt Maiocco and Jennifer Lee Chan discuss how the 49ers have set themselves up well in the division with an undefeated start, and if a character-defining win like tonight can catapult them to their larger goals despite the early adversity they've experienced thus far.

Transcribed - Published: 3 October 2025

John Lynch joins Matt Maiocco to break down the 49ers' first four games of the 2025 NFL season, from how San Francisco's rash of injuries affect his front-office priorities to some of the more positive on-field developments during their resilient start. Jennifer Lee Chan also joins Matt to preview the 49ers' Week 5 matchup vs. the NFC West rival Los Angeles Rams this Thursday at SoFi Stadium, and points out an area of vulnerability San Francisco could expose on a short week against a very potent opponent.

Transcribed - Published: 1 October 2025