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49ers Talk: A San Francisco 49ers Podcast

49ers Talk: A San Francisco 49ers Podcast

NBC Sports Bay Area

Nfl, Football, Matt Maiocco, San Francisco 49ers, Sports

4.6988 Ratings

Overview

NBC Sports Bay Area 49ers insider Matt Maiocco and reporter Jennifer Lee Chan bring you comprehensive NFL coverage of all things San Francisco 49ers. Don't miss weekly in-depth interviews with players, coaches, front-office personnel, alumni and fellow media members. Check out all new episodes year-round.

858 Episodes

49ers get job done vs. Titans as pressure builds in playoff race

It wasn't a picture-perfect performance Sunday vs. the Titans, but the 49ers returned from their bye week energized and executed when they needed to on their way to 37-24 victory at Levi's Stadium. Offensively, they looked sharp and scored on their first five possessions. Quarterback Brock Purdy threw for three touchdowns and zero interceptions as Ricky Pearsall finally broke through with a team-high 96 receiving yards and Jauan Jennings added two touchdowns. San Francisco's defense was tested, however, and will need to promptly turn things around with three regular-season games left and a ton on the line. On this episode of "49ers Talk," co-hosts Matt Maiocco and Jennifer Lee Chan discuss how San Francisco's offense is jelling at the right time, and how Purdy's confidence is contagious to the whole position group. They also detail how the 49ers' defense will need to step up amid a heated playoff race within their conference and, most importantly, their own division. San Francisco's postseason future is right in front of them, and they will play a large role in how it plays out down the stretch.

Transcribed - Published: 15 December 2025

Kyle Shanahan, Greg Papa break down 49ers-Titans with NFC playoff positioning up for grabs

Kyle Shanahan joins "49ers Talk" co-host Matt Maiocco to discuss the challenges and benefits a late bye week presents San Francisco down the final stretch of the season. Matt asks Kyle how QB Brock Purdy can finish the season strong, evaluates wideout Ricky Pearsall's usage, and how the idea of meaningful December football can motivate his team. Greg Papa also joins Matt on this episode to break down how a young Tennessee Titans team with little to lose can present a dangerous obstacle for the 49ers. Papa points out where the 49ers need to fortify their resources on defense and if this is the game Pearsall can return to his early-season production

Transcribed - Published: 13 December 2025

Patrick Willis exclusive: Legendary linebacker excited for Super Bowl, applauds 49ers' perseverance

Hall of Fame linebacker Patrick Willis, now an Alumni Ambassador for San Francisco after spending his entire career in the Bay, joins "49ers Talk" co-host Matt Maiocco to discuss the impact Super Bowl LX can have on the region and how its immersive, family-friendly festivities can be enjoyed by all who attend -- whether they have a ticket or not. Patrick and Matt also tackle the 49ers' surprising run this season and how overcoming adversity has been a hallmark of their success. Willis expands on what San Francisco needs to focus on in its final four games, as well as how his relationship with the organization affords him the opportunity to connect with upcoming great 49ers players. Jennifer Lee Chan also joins Matt to paint the NFC playoff picture, review roster changes and injury updates, plus detail San Francisco's final stretch.

Transcribed - Published: 11 December 2025

49ers' playoff standing improves during Week 14 bye as other NFC contenders clash

The 49ers enjoyed a bump in their playoff position without lifting a finger in their bye week, the last of the NFL season. The other teams battled it out in a blockbuster of matchups with gargantuan postseason implications across the board in both NFL conferences. In the NFC, the Green Bay Packers leapfrogged the Chicago Bears to take the No. 2 overall seed while dropping their division rivals to the seventh and final wild-card position, a precipitous fall for an opponent in one afternoon of work. The 49ers will play those Bears in a Sunday night clash in Week 17, which surely will intrigue. But, first come the Tennessee Titans in a matinee next Sunday, a potent opponent with nothing to lose. On this episode of "49ers Talk," co-hosts Matt Maiocco and Jennifer Lee Chan look ahead to San Francisco's final four games, a stretch that will test it in all phases and could define the rest of the team's entire season.

Transcribed - Published: 8 December 2025

GM John Lynch eyes big finish for 49ers in wide-open NFC playoff race

President of Football Operations/General Manager John Lynch joins '49ers Talk,' co-host Matt Maiocco for an update on the organization before San Francisco starts its final stretch of the 2025 NFL season. Lynch detailed the pride he has for the 49ers enduring tremendous adversity to place themselves squarely in the NFC playoff race before offering his expectations for the rest of the season. Jennifer Lee Chan also joins Maiocco to break down the 49ers' chances of making a deep playoff run as San Francisco begins to hit its stride.

Transcribed - Published: 6 December 2025

Is this Kyle Shanahan's best staff yet? Plus, CMC advocates for Roger Craig to enter HOF

Its Week 14 in the NFL, and the 49ers finally have reached their bye. As San Francisco players rest and recuperate, "49ers Talk" co-hosts Matt Maiocco and Jennifer Lee Chan take a pulse on the 49ers' season with just four regular-season games left. Jennifer, Matt, and later Greg Papa, discuss if Kyle Shanahan's current coaching staff is his best yet, and if that makes him a strong candidate for his first NFL Coach of the Year award. They also detail the 49ers' latest injuries and roster additions, then discuss if Christian McCaffrey's public support of Roger Craig can convince the Pro Football Hall of Fame committee to induct the legendary 49ers running back.

Transcribed - Published: 3 December 2025

Brock Purdy, 49ers improve to 9-4 after bulldozing Browns in impressive road win

The 49ers, on Sunday, notched their first three-game winning streak since the opening three weeks of the season and won in Cleveland for the first time since Nov. 1984. The 49ers' latest win was exhibition in execution from the kickoff as they played complimentary football in all three phases. Brock Purdy played errorless football with excellent decision-making, while extending plays when needed. The special teams group bolstered the 49ers' field-position on returns and made timely kicks when needed, while the defense has been humming the last few weeks, creating turnovers and finally adding an element of pressure from the D-line that spurred San Francisco to victory. On this episode of '49ers Talk,' co-hosts Matt Maiocco and Jennifer Lee Chan break down San Francisco's decisive 26-8 road win over the Cleveland Browns at Huntington Bank Field. From Brock Purdy's bounce-back performance following a mistake-filled game, to special teams and defensive units flourishing, to a coach committed to his preparation and scheme in what might be his best coaching season for the Faithful, Matt and Jennifer detail a team finding health and success in time for a much-needed break during their Week 14 bye week.

Transcribed - Published: 1 December 2025

John Lynch previews 49ers-Browns, addresses Brandon Aiyuk's status with organization

San Francisco's president of football operations John Lynch sat down with “49ers Talk” host Matt Maiocco this week to preview their Week 13 matchup vs. the Cleveland Browns and provide organizational news and updates. Maiocco and Lynch also discuss how Brock Purdy can bounce back in Week 13 following a poor display against the Carolina Panthers, Brandon Aiyuk's current relationship with the organization in light of his contract situation, and how San Francisco's special teams group has turned from a liability last season into a weapon this year. Finally, Maiocco provides injury updates that will affect the 49ers' defense Sunday and names the five key San Francisco players to watch in Week 13.

Transcribed - Published: 29 November 2025

49ers brace for brutal weather vs. Browns as NFC playoff race tightens

The 49ers are entrenched in the final NFC playoff spot as they prepare to face the Cleveland Browns. However, with low temperatures, high-winds, and possible perception forecast for Sunday's matchup, holding onto that precious wild card spot might be more complicated. Having lost their previous contest in Cleveland under similar conditions in 2023, San Francisco will be tasked with executing their offense more efficiently this time while mitigating current NFL sack leader Myles Garrett. On this episode of "49ers Talk," co-hosts Matt Maiocco and Jennifer Lee Chan discuss Brock Purdy's regression last week against the Panthers and how he and the 49ers' offense can minimize mistakes against familiar obstacles in inclement weather and a formidable pass-rush. Also, Matt and Jennifer provide injury updates, surprising takes on a San Francisco offensive line playing well under-the-radar and where the 49ers might look in the draft. They also praise the evolution of Christian McCaffrey's game during an incredible individual season.

Transcribed - Published: 27 November 2025

49ers keep pace in NFC playoff picture with prime-time win vs. Panthers

The 49ers entered Monday night knowing the needed a win to distance themselves from another NFC playoff contender in the Carolina Panthers. Despite three uncharacteristic interceptions from quarterback Brock Purdy, the 49ers' defense stepped up to secure a 20-9 victory as safety Ji'Ayir Brown's two interceptions helped San Francisco hold Carolina to single digits. On this episode of "49ers Talk," co-hosts Matt Maiocco and Jennifer Lee Chan discuss Purdy's dip in form and whether he's physically 100 percent, linebacker Curtis Robinson's long-awaited first NFL start and Brown's career night. Finally, wide receiver Brandon Aiyuk's curious contract situation is highlighted: With five regular-season games remaining, will he return? And what are the motivating factors for both parties if he does?

Transcribed - Published: 25 November 2025

Kyle Shanahan, Greg Papa break down 49ers’ Week 12 game vs. Panthers as CMC faces former team

“49ers Talk” host Matt Maiocco discusses the latest news on Brandon Aiyuk before speaking with coach Kyle Shanahan about San Francisco's Week 12 matchup vs. the Carolina Panthers on Monday night. Also, Greg Papa joins Matt to discuss Brock Purdy’s performance against the Arizona Cardinals in Week 11 and reflect on the trade that brought Christian McCaffrey to the 49ers.

Transcribed - Published: 22 November 2025

Christian McCaffrey faces former Panthers team in Week 12 matchup

On this episode of "49ers Talk," co-hosts Matt Maiocco and Jennifer Lee Chan reflect on the blockbuster trade that brought Christian McCaffrey to San Francisco ahead of Monday night's matchup against his former team. Additionally, Matt and Jennifer discuss how a healthy 49ers offense will improve their run game. Matt then sits down with defensive back Deommodore Lenoir to discuss his growth as a leader and team captain of the 49ers’ defense.

Transcribed - Published: 21 November 2025

Brock Purdy's return ignites Christian McCaffrey, George Kittle as 49ers thrash Cardinals

Brock Purdy's return sparked the 49ers' offense, it also brought a much needed divisional win in a blowout against the Cardinals. Purdy threw for three touchdowns on Sunday, two of which went to a favorite target in tight end George Kittle and the other went to offensive fulcrum Christian McCaffrey, who leads the NFL in scrimmage yards this season through Week 11. Skyy Moore set the tone, returning the opening kickoff 98 yards to the 1-yard line, setting up a McCaffrey 1-yard touchdown run. San Francisco maintained control throughout the game, one in which Arizona did itself no favors accumulating a franchise-record 17 penalties. San Francisco did not escape Arizona unscathed though, as kicker Eddy Piñeiro suffered a hamstring injury in the third quarter that could force the team to bring in a new kicker. On this episode of '49ers Talk,' co-hosts Matt Maiocco and Jennifer Lee Chan break down San Francisco's outstanding performance against the Cardinals Sunday at State Farm Stadium. Matt and Jennifer discuss the impact of Purdy's return on the 49ers' offense during a crucial stretch, Kittle and CMC's dominance, and how injuries to both Piñeiro and linebacker Tatum Bethune might affect the team ahead of Monday's showdown with the Carolina Panthers.

Transcribed - Published: 17 November 2025

Kyle Shanahan, Greg Papa discuss 49ers' Week 11 game vs. Cardinals, Brock Purdy’s return from injury

“49ers Talk” hosts Matt Maiocco and Jennifer Lee Chan provide the latest roster updates before Matt speaks with coach Kyle Shanahan about San Francisco's Week 11 matchup vs. the Arizona Cardinals. Also, Greg Papa joins Matt to discuss Brock Purdy’s return for Sunday’s game and how he could revitalize the Niners for the rest of the season.

Transcribed - Published: 15 November 2025

All eyes on QB1 as Brock Purdy gears up for 49ers return in Week 11

Brock Purdy returned to practice Wednesday, taking the 49ers' first-team reps at quarterback with a goal of returning in Week 11 against the Arizona Cardinals. Wide receiver Ricky Pearsall, who, like Purdy, has been missing from San Francisco's starting lineup since Week 4, also returned to the practice field. On this episode of "49ers Talk," co-hosts Matt Maiocco and Jennifer Lee Chan discuss how the potential return of two impact players will help the 49ers' offense. Additionally, Matt and Jennifer look ahead to how the 49ers can solidify a playoff spot as they approach a pivotal stretch in their schedule. As far as depth is concerned, Matt and Jennifer debate the balance of player development during a postseason push and how to balance two very important pillars to the season.

Transcribed - Published: 13 November 2025

Rams' offense dominates depleted 49ers in NFC West showdown

Matthew Stafford and the Rams' high-powered offense overpowered a 49ers defense reeling from injuries on Sunday, handing San Francisco its first divisional loss with a 42-26 defeat. The 49ers remain locked in the NFC West's third-place spot, fighting for health and positioning as the playoff picture starts to crystallize in the season's second half. On this episode of "49ers Talk," co-hosts Matt Maiocco and Jennifer Lee Chan break down San Francisco's performance against the Rams in Week 10, from an inexperienced defense decimated by injuries to an offense expected to protect such deficiencies despite its own missing pieces. Matt and Jennifer help make sense of how San Francisco can contend moving forward in a highly competitive divisional and conference environment.

Transcribed - Published: 10 November 2025

Kyle Shanahan, Greg Papa discuss key matchups in 49ers' Week 10 game vs. Rams

49ers insider Matt Maiocco provides the latest injury updates before speaking with head coach Kyle Shanahan about San Francisco's Week 10 matchup vs. the Los Angeles Rams. Matt also sits down with tight end George Kittle to discuss how he prepares for game day every week, and his love for cinema. Finally Greg Papa joins Matt to discuss key matchups for Sunday’s game and how it is a must-win for the Niners.

Transcribed - Published: 8 November 2025

49ers stick to their strategy as trade deadline passes without a move

The NFL trade deadline came and went Tuesday, and the 49ers stood pat with the roster they have. San Francisco's quiet approach spoke volumes about their intent despite fervor from fans, sticking to their path of growth and development with youth. At 6-3, the 49ers can compete -- and they've decided to do so with the current players at their disposal. On this episode of "49ers Talk," co-hosts Matt Maiocco and Jennifer Lee Chan discuss San Francisco's choice to trust its depth and chemistry over a splashy trade that would mortgage their future. Also, as Brock Purdy and Ricky Pearsall continue rehabbing their injuries, just how close are they to returning? Finally, Matt and Jennifer debate if the 49ers can strike gold again against the Los Angeles Rams after their rivals' Week 5 theatrics.

Transcribed - Published: 6 November 2025

49ers bounce back in Week 9 with decisive victory over Giants

The 49ers bounced back in a big way with a statement win over the New York Giants. San Francisco was laser focused in all three phases, never looking back after taking a second-quarter lead. The 49ers' offense was humming all afternoon, scoring a season-high 34 points while Christian McCaffrey added a pair of touchdowns along with 173 total yards. San Francisco's win didn't come without cost, as 2025 first-round draft pick Mykel Williams went down with a knee injury late in the fourth quarter. On this episode of "49ers Talk," co-hosts Matt Maiocco and Jennifer Lee Chan break down how the 49ers responded to their disappointing loss against the Houston Texans with an offensive outburst in Sunday's win over New York. They also review how Williams' potential loss could affect the 49ers' approach at the NFL trade deadline. Finally, with a pivotal divisional matchup with the Los Angeles Rams looming, Matt and Jennifer discuss Brock Purdy's progress as the quarterback works back from a toe injury.

Transcribed - Published: 3 November 2025

Kyle Shanahan discusses 49ers' Week 9 matchup vs. Giants, impact of George Kittle’s return

Matt Maiocco speaks with 49ers coach Kyle Shanahan about San Francisco's Week 9 matchup vs. the New York Giants and how he scripts his first 24 offensive plays. Also, Greg Papa joins Matt to assess the 49ers’ season at the halfway point and discuss key matchups for Sunday’s game.

Transcribed - Published: 1 November 2025

How does 49ers trade acquisition Keion White fit with team?

In need of reinforcements along their injured defensive line, the 49ers made a trade with the New England Patriots for defensive end Keion White and a 2026 seventh-round draft pick in exchange or a 2026 sixth-rounder. Matt Maiocco and Jennifer Lee Chan discuss how White bolsters a 49ers defensive line whose nine sacks are tied for the second-fewest among all NFL teams this season. Matt also sits down with NBC Sports Boston's Patriots insider Phil Perry to examine White's time with the organization as a former second-round pick of the 2023 NFL Draft. Lastly, Jennifer and Matt review if the 49ers would entertain any other trades, assess rookie Mykel Williams' stock through eight games and provide 49ers injury updates before San Francisco's Week 9 game against the New York Giants at MetLife Stadium.

Transcribed - Published: 30 October 2025

49ers' slow start stunts comeback in Week 8 loss to Texans

The 49ers came into Week 8 knowing the Texans' defense was elite, but it was Houston's struggling offense that took over Sunday at NRG Stadium. Heavily scrutinized QB C.J. Stroud executed a sound game plan for the Texans, while 49ers teammates George Kittle and Jake Tonges each caught a touchdown on on national Tight Ends Day to keep San Francisco's comeback hopes alive. San Francisco's offense lacked much rhythm beyond that, and the disjointed display effectively ended in a 26-15 loss, their third of the season. On this episode of "49ers Talk," co-hosts Matt Maiocco and Jennifer Lee Chan break down what went wrong with San Francisco on both sides of the ball, which injuries will further affect the 49ers' depleted depth and how they can turn a performance like this around in Week 9 vs. the New York Giants at MetLife Stadium.

Transcribed - Published: 27 October 2025

Mac Jones to start again for 49ers against DeMeco Ryans' Texans

Matt Maiocco sits down with 49ers coach Kyle Shanahan to discuss the team's upcoming Week 8 matchup vs. DeMeco Ryans' Houston Texans. Also, Greg Bethune, father of San Francisco linebacker Tatum Bethune, joins the show to discuss his son's journey to the NFL

Transcribed - Published: 25 October 2025

Eddy Piñeiro exclusive: 49ers kicker shares journey to finding home with Faithful

Eddy Piñeiro leads the NFL in made field goals without a miss through Week 7, but the 49ers kicker's journey to San Francisco has been anything but perfect. Jennifer Lee Chan sits down with Piñeiro, who shares why he chose to play for the 49ers after Jake Moody's release and how close he came to signing elsewhere. Piñeiro discusses how he brings a jolt to the 49ers' locker room, his fast-growing bond with George Kittle and why football was second to his first love in sport, soccer. Also, Matt Maiocco and Jennifer review the midweek list of 49ers injuries and who might start in Week 8 vs. the Houston Texans.

Transcribed - Published: 23 October 2025

49ers pass prime-time test in methodical 20-10 win vs. Falcons

Without their fearless leader, Fred Warner, the 49ers' defense produced a masterclass performance against the red-hot Atlanta Falcons on Sunday while the offense ran all over the field. Matt Maiocco and Jennifer Lee Chan discuss how San Francisco produced one of its most complete performances this season as players stepped up and embraced the challenge of facing a top opponent. With the return of George Kittle and many backups stepping up, the 49ers proved they might have been down, but they sure aren't out.

Transcribed - Published: 20 October 2025

Kyle Shanahan discusses 49ers' Week 7 matchup vs. Falcons, impact of Fred Warner’s season-ending injury

Matt Maiocco speaks with 49ers coach Kyle Shanahan about San Francisco's Week 7 matchup against the Atlanta Falcons, and how losing Fred Warner for the season will impact their young defensive players. Also, Jennifer Lee Chan joins the show for an exclusive interview with NBC Sports NFL broadcaster Cris Collinsworth and analyst Devin McCourty to discuss the loss of Warner, Nick Bosa and more.

Transcribed - Published: 18 October 2025

Kendrick Bourne details his evolution amid second 49ers stint

After a long NFL journey, wide receiver Kendrick Bourne is back with the team who first took a chance on him, and he's beyond grateful for his second 49ers stint. Bourne sits down with '49ers Talk' co-host Matt Maiocco to discuss his path back to San Francisco and how the time away made his return that much sweeter. Bourne details his development over his nine NFL seasons and why he's so happy to be back in the Bay Area. Also, Bourne shares the intricacies of playing wide receiver in Kyle Shanahan's offense and how he values the relationships he has built with fellow teammates like Mac Jones and Ricky Pearsall. Finally, Jennifer Lee Chan and Matt discuss the daunting task of a primetime matchup vs. a surging Atlanta Falcons team and who we could expect to lineup at QB and other key positions in Week 7.

Transcribed - Published: 16 October 2025

Fred Warner's season-ending injury steals spotlight in 49ers' Week 6 loss to Buccaneers

The 49ers' health woes continued after San Francisco lost superstar linebacker Fred Warner to a season-ending ankle injury in Sunday's loss to the Tampa Bay Buccaneers. San Francisco responded valiantly, managing to stay competitive throughout the matchup before fading late in the fourth quarter. Baker Mayfield and the Bucs' high-powered offense proved to be too much in the end as the 49ers suffered their second loss of the season. On this episode of '49ers Talk,' co-hosts Matt Maiocco and Jennifer Lee Chan discuss the potential ramifications of Warner's season-ending injury. They then detail Warner's impact on the 49ers organization from ownership to players and how San Francisco will feel his loss both on and off the field. Finally, they deliberate if Warner's injury signifies the beginning of the end in what started out as a promising 49ers' season?

Transcribed - Published: 13 October 2025

Kyle Shanahan discusses 49ers' Week 6 matchup vs. Buccaneers, Alfred Collins’ rookie surge

Matt Maiocco speaks with 49ers coach Kyle Shanahan about San Francisco's Week 6 matchup vs. the Tampa Bay Buccaneers and how rookie defensive lineman Alfred Collins has made significant strides this season. Also Greg Papa joins Matt to discuss what QB3 Adrian Martinez will bring to 49ers' offense if Mac Jones gets injured on Sunday.

Transcribed - Published: 11 October 2025

Christian McCaffrey exclusive: 49ers star states 'feelings don't matter'

Star 49ers running back Christian McCaffrey is off to a hot start offensively this season, showing shades of his 2023 AP Offensive Player of the Year campaign. McCaffrey sits down with Matt Maiocco to discuss a plethora of topics, such as learning route-running from his Super Bowl-winning father, identifying the most valuable asset in professional football and describing how George Kittle helps bring "fun" back into the game. Also, Jennifer Lee Chan stops by to update the 49ers' lengthy injury list and preview the potent Buccaneers offense San Francisco will face in Week 6, led by quarterback Baker Mayfield.

Transcribed - Published: 9 October 2025

Greg Papa dissects shorthanded 49ers’ improbable 26-23 OT win over the Rams

Matt Maiocco shares the 49ers’ injury update before sitting down with Greg Papa to recap San Francisco’s thrilling 26-23 overtime win over the Los Angeles Rams on Thursday night at SoFi Stadium and discuss how the victory can set the tone for the rest of the season.

Transcribed - Published: 5 October 2025

49ers remain atop NFC West after Mac Jones' gutsy performance vs. Rams

An injured 49ers squad defied the odds and dug deep for a 26-23 overtime win over the Los Angeles Rams on Thursday at SoFi Stadium. Backup quarterback Mac Jones delivered his third win in three starts despite laboring through pain all game. Kyle Shanahan managed a very limited and at times inexperienced San Francisco squad, and rookies produced when their numbers were called. Matt Maiocco and Jennifer Lee Chan discuss how the 49ers have set themselves up well in the division with an undefeated start, and if a character-defining win like tonight can catapult them to their larger goals despite the early adversity they've experienced thus far.

Transcribed - Published: 3 October 2025

John Lynch evaluates 49ers' up-and-down start to 2025 NFL season

John Lynch joins Matt Maiocco to break down the 49ers' first four games of the 2025 NFL season, from how San Francisco's rash of injuries affect his front-office priorities to some of the more positive on-field developments during their resilient start. Jennifer Lee Chan also joins Matt to preview the 49ers' Week 5 matchup vs. the NFC West rival Los Angeles Rams this Thursday at SoFi Stadium, and points out an area of vulnerability San Francisco could expose on a short week against a very potent opponent.

Transcribed - Published: 1 October 2025

Costly mistakes plague 49ers in first loss of 2025 NFL Season

An afternoon of errors resulted in the 49ers' first loss of the 2025 NFL season Sunday against the Jacksonville Jaguars. Despite a second-half comeback attempt, San Francisco couldn't overcome its four turnovers. Brock Purdy's looked shaky in his return from injury after missing the last two weeks with turf toe. Matt Maiocco and Jennifer Lee Chan discuss how a subpar performance from all three phases contributed to the 49ers' first defeat. Matt and Jennifer also address the curious postgame exchange between 49ers defensive coordinator Robert Saleh and Jaguars coach Liam Coen as the topic of sign-stealing could be a season-long storyline.

Transcribed - Published: 29 September 2025

Kyle Shanahan previews 49ers' Week 4 matchup vs. Jaguars, Brock Purdy returns from injury

Matt Maiocco speaks with 49ers coach Kyle Shanahan about San Francisco's Week 4 matchup vs. the Jacksonville Jaguars and also discusses Nick Bosa’s season-ending ACL injury. Greg Papa joins Matt to discuss defensive coordinator Robert Saleh’s comments about the Jaguars’ signal stealing and Brock Purdy returning from injury.

Transcribed - Published: 27 September 2025

49ers take next-man-up mentality into Week 4 vs. Jaguars

Despite their undefeated status, the Nick Bosa-less 49ers must persevere as the Jacksonville Jaguars visit Levi's Stadium this Sunday. Matt Maiocco and Jennifer Lee Chan discuss who will step up in Bosa's place and how San Francisco can adapt in other injury-bitten position groups. Plus, Matt and Jennifer detail how Demarcus Robinson will integrate back into the fold and how it affects the receiving corps. Finally, the nominees for the Pro Football Hall of Fame's Class of 2026 have been announced, and Matt and Jennifer choose the most outstanding former 49er candidates.

Transcribed - Published: 25 September 2025

Emergency Podcast: 49ers DE Nick Bosa reportedly out for remainder of season with torn ACL

The 49ers have endured a rash of injuries to star players to start their season, and that list grew emphatically by one more player Monday morning following the news that defensive end Nick Bosa reportedly will have to undergo season-ending surgery to repair a torn ACL. On this emergency episode of '49ers Talk,' Matt Maiocco is joined by Carlos Ramirez to discuss the fallout from this massive injury. How will the 49ers proceed, who will step-up in place of the former NFL Defensive Player of the Year, can San Francisco bring in reinforcements externally and will that change their current strategy of roster-construction? Matt and Carlos tackle these tough questions as the undefeated 49ers must find answers just three weeks into the NFL regular season.

Transcribed - Published: 22 September 2025

Eddy Piñeiro's game-winning field goal powers 49ers' gritty win over Cardinals in home opener

The 49ers' home opener against the Arizona Cardinals brought plenty of twists and turns as San Francisco emerged victorious to maintain its undefeated start with a thrilling 16-15 win. Kicker Eddy Piñeiro's game-winning field goal and Mac Jones' clinical two-minute drive got the 49ers over the hump in a gutsy win, improving San Francisco to 3-0 in the 2025 season. The win didn't come without its costs as star defensive end Nick Bosa exited the game with an apparent knee injury. Matt Maiocco and Jennifer Lee Chan break down the 49ers' courageous victory, Bosa's injury and how San Francisco's alleged weakness in depth has turned into their strength as they now sit atop the NFC West standings.

Transcribed - Published: 22 September 2025

Kyle Shanahan previews 49ers' Week 3 matchup vs. Cardinals, Mykel Williams’ versatility on defense

Matt Maiocco speaks with 49ers coach Kyle Shanahan about their Week 3 matchup vs. the Arizona Cardinals and discuss how Luke Farrell and Jake Tonges have stepped up after injuries to George Kittle and Kyle Juszczyk. Also Greg Papa joins Matt to breaks down how 49ers’ improved speed on defense can contain Kyler Murray.

Transcribed - Published: 20 September 2025

Dee Winters exclusive: How 49ers linebacker has earned his starting role

Dee Winters' journey to starting 49ers linebacker opposite star Fred Warner didn't come without its bumps in the road. From past injuries to supplanting himself next to a dynamic duo of Warner and Dre Greenlaw, it was always going to be uphill. Winters, however, has weathered the storm and emerged as the promising player San Francisco hoped he would be when it drafted him in the sixth round of the 2023 NFL Draft. On this episode of "49ers Talk," Matt Maiocco sits down with the third-year pro to discuss his journey from humble beginnings to the primetime of 49ers football. Also, co-host Jennifer Lee Chan joins Matt to discuss injury updates to QB Brock Purdy and the other San Francisco stars, as well as preview the Week 3 lineup vs. the Arizona Cardinals.

Transcribed - Published: 18 September 2025

Mac Jones steps up admirably in 49ers' Week 2 win vs. Saints

Mac Jones might have rebooted his career in the 49ers' 26-21 win over the New Orleans Saints on Sunday at Caesars Superdome. Under the tutelage of San Francisco coach Kyle Shanahan, Jones looked the part of an NFL starting quarterback with a 279-yard, three-touchdown performance as an injured Brock Purdy watched from the sideline. Matt Maiocco and Jennifer Lee Chan break down how the 49ers' offense utilized Jones' arm early and often, and also identify which rookies stepped up amid injuries on both offense and defense ahead of next weekend's home opener against the Arizona Cardinals.

Transcribed - Published: 15 September 2025

Kyle Shanahan previews 49ers-Saints matchup, Mac Jones' San Francisco debut

Matt Maiocco speaks with 49ers coach Kyle Shanahan about their Week 2 matchup vs. the New Orleans Saints and Mac Jones' San Francisco debut on Sunday in place of injured starting quarterback Brock Purdy. Also Greg Papa joins Matt to break down key matchups in this weekend's game.

Transcribed - Published: 13 September 2025

Emergency Podcast: 49ers waive beleaguered kicker Jake Moody, will sign veteran Eddy Piñeiro

The 49ers brought an end to the Jake Moody saga Tuesday by waiving the beleaguered kicker, opting to bring in veteran Eddy Piñeiro as his replacement. Matt Maiocco and Jennifer Lee Chan break down how San Francisco and Moody arrived to this point and how the 49ers will fare at this position moving forward. The duo also discusses Brock Purdy's pair of injuries and George Kittle's placement on injured reserve, as well as Kendrick Bourne's return. Then, Matt sits down with Jake Tonges' former high school coach to discuss the backup tight end's emergence from Los Gatos, Calif., to the pros.

Transcribed - Published: 10 September 2025

Brock Purdy, Nick Bosa come up clutch in 49ers' Week 1 win over Seahawks

The 49ers rallied late for a 17-13 comeback victory over the Seattle Seahawks on Sunday at Lumen Field. While San Francisco's defense produced several key performances, a surprising face on offense made the play of the game when third-string tight end Jake Tonges stepped up in George Kittle's injury absence. Matt Maiocco and Jennifer Lee Chan break down the roller-coaster ride that was the 49ers' Week 1 win, from outstanding defense and gritty offense to their erratic special-teams play.

Transcribed - Published: 8 September 2025

Kyle Shanahan previews 49ers' season opener, Christian McCaffrey listed as questionable

Matt Maiocco speaks with San Francisco 49ers coach Kyle Shanahan about their Week 1 matchup vs. the Seattle Seahawks and why he's optimistic about Christian McCaffrey's health despite the star running back being listed as questionable for Sunday's game. Greg Papa also joins to provide an encouraging update on his cancer battle.

Transcribed - Published: 6 September 2025

Brock Purdy exclusive: How 49ers QB balances stardom with perspective

As 49ers quarterback Brock Purdy leads San Francisco into its 2025 NFL season opener, gone are the days of Mr. Irrelevant. Equipped with a lucrative new contract and a young family in tow, Purdy sits down "49ers Talk" host Matt Maiocco to discuss how he adjusts to all of these changes, including a complete roster overhaul this offseason. Brock and Matt touch upon what motivates the 25-year-old and he can take his game and the 49ers organization to the next level, one snap at a time.

Transcribed - Published: 4 September 2025

Will Jauan Jennings suit up for the 49ers' season opener vs. Seahawks?

With Sunday’s season opener against the Seattle Seahawks looming, Matt Maiocco and Jennifer Lee Chan discuss the latest updates on Jauan Jennings’ calf injury and contract extension negotiations, and debate if Jennings will suit up for the 49ers in Week 1. Also, Matt and Jennifer break down San Francisco's wide-receiver depth and detail what Brian Robinson Jr. brings to the team's run game.

Transcribed - Published: 31 August 2025

Breaking down surprises, takeaways from 49ers' initial 53-man roster

With Tuesday's roster cutdown deadline officially passed, there were a few surprises for the 49ers at key positions. Matt Maiocco and Jennifer Lee Chan discuss their biggest takeaways from San Francisco's initial 53-man roster, from the ailing wide-receiver corps and heavily invested defensive line, to a special-teams group facing mounting pressure. Also, we'll hear from newly acquired running back Brian Robinson Jr., who is poised to make the 49ers' backfield the most potent in the league.

Transcribed - Published: 27 August 2025

49ers turn to roster cuts after beating Chargers in preseason finale

After the 49ers' 30-23 win over the Los Angeles Chargers in Saturday's preseason finale, their attention now turns to the 53-man roster deadline on Tuesday. Matt Maiocco and Jennifer Lee Chan discuss each position group's depth and how Kyle Shanahan, John Lynch and Co. will whittle the roster down. New additions Skyy Moore and Brian Robinson Jr. join the team as roster locks, but which players will be cut? Also, Matt sits down with NBC Sports Washington's JP Finlay to discuss what the Robinson trade brings to the 49ers' locker room.

Transcribed - Published: 24 August 2025

49ers' roster taking shape ahead of preseason finale vs. Chargers

With former 49ers coach Jim Harbaugh and the Los Angeles Chargers visiting Levi's Stadium for Saturday's preseason finale, San Francisco's final roster decisions are becoming more clear. Matt Maiocco and Jennifer Lee Chan discuss what will play into the 49ers' roster choices, including injury updates, player suspensions and position-group competitions. Also, Matt and Jennifer review how the entire 2025 NFL Draft class has fared throughout training camp, and discuss Kyle Shanahan's update on veteran wide receiver Demarcus Robinson's suspension following his violation of the NFL's personal conduct policy last season.

Transcribed - Published: 21 August 2025

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