Fred Warner's season-ending injury steals spotlight in 49ers' Week 6 loss to Buccaneers

49ers Talk: A San Francisco 49ers Podcast

NBC Sports Bay Area

Nfl, Football, Matt Maiocco, San Francisco 49ers, Sports

4.6 • 988 Ratings

🗓️ 13 October 2025

⏱️ 37 minutes

🔗️ Recording | iTunes | RSS

🧾️ Download transcript

Summary

The 49ers' health woes continued after San Francisco lost superstar linebacker Fred Warner to a season-ending ankle injury in Sunday's loss to the Tampa Bay Buccaneers. San Francisco responded valiantly, managing to stay competitive throughout the matchup before fading late in the fourth quarter. Baker Mayfield and the Bucs' high-powered offense proved to be too much in the end as the 49ers suffered their second loss of the season. On this episode of '49ers Talk,' co-hosts Matt Maiocco and Jennifer Lee Chan discuss the potential ramifications of Warner's season-ending injury. They then detail Warner's impact on the 49ers organization from ownership to players and how San Francisco will feel his loss both on and off the field. Finally, they deliberate if Warner's injury signifies the beginning of the end in what started out as a promising 49ers' season?

Transcript

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0:00.0	Savings. Big O savings. Right now, prepare for fall with $80 to $100 instant savings on four select in stock tires with installation purchase. Plus zero interest if paid in full within 12 or six months. Big O tires, the team you trust.
0:20.0	It was an absolutely crushing day for the 49ers. The loss to the Tampa Bay Buccaneers was one thing, but this was destined to be a bad day, just seven minutes into the game when Fred Warner went down with a horrific leg injury. The 49ers were already going to be without Nick Bosa for the rest of the season, and now Warner is out as well.
0:40.8	Where do the 49ers go from here without their top two defensive players and maybe the two players on the entire team they could least afford to lose?
0:50.0	Jennifer Lee Chan is in Tampa, Florida, where she will describe the scene as the 49ers got set to travel back to the Bay Area.
0:57.2	We'll have all that and much more on this episode of 49ers talk coming at you right now.
1:01.8	Welcome to another episode of 49ers talk on NBC Sports Bay Area.com.
1:08.1	Introducing your hosts, Matt Mayoko and Jennifer Lee Chan.
1:12.4	All right. This is 49ers talk brought to you by Big O Tires. Shop, top brand tires with the
1:17.0	low price guarantee. Set an appointment at Bigotires.com and drive away knowing you got the best
1:22.7	deal on the road at Big O. Big O tires, the team you trust. And the 49ers in this week six game against the Tampa
1:31.1	Bay Buccaneers, they come out of it as a 30 to 19 loser, but nobody is talking too much about
1:38.2	the win-loss column after this one, Jennifer, because of the just devastating injury that
1:44.1	all pro linebacker Fred Warner sustained.
1:47.5	I mean, and the reverberating theme in the locker room is that he is the heartbeat of the team.
1:53.7	And he really is.
1:54.8	Everything he does from the way he works out to the way he practices, to the way he recovers his
2:00.4	body, to the way he plays on the field way he recovers his body, to the way he
2:01.3	plays on the field. He is the heart and soul of this team, not just on the defensive side,
2:06.8	but on the offensive side. And it was an extremely somber locker room, not just from the players,
2:13.6	but from the coaching staff from Jed York and John Lynch, who walked into the locker
2:18.7	room, Parag Marante, Al Guido, everybody that came to the locker room that we saw was just,
2:24.5	you could tell that it was, it was literally gut-wrenching for everybody to come in.
	...

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