The Proof with Simon Hill

In this episode I sit down again with microbiome researcher Dr Suzanne Devkota to explore what a healthy microbiome really is and how we can support it. We unpack diversity, early life programming, fibre and microbiota accessible carbohydrates (MACs), plus the genuine role of probiotics, prebiotics and postbiotics. Suzanne also shares cutting edge research on short chain fatty acids, Akkermansia, inflammatory bowel disease, visceral fat and colon cancer, and helps separate solid science from the noise you see online. What We Cover What the microbiome is and how it differs along the digestive tract Why diversity is a key marker of gut health and how chronic disease and diet affect it Early life influences on the microbiome, from birth mode to first foods The realities of stool testing, different methods, and how to interpret results with care Probiotics versus prebiotics versus postbiotics, when each may or may not be useful MAC rich foods, short chain fatty acids and why butyrate is so important for gut barrier integrity The Akkermansia story, mucus, leaky gut and why focusing on one bug is misleading New data on IBD, gut leakiness, bacteria in fat tissue and links to fibrosis and metabolism I hope this conversation gives you a clearer, more grounded view of gut health and helps you focus on practical, sustainable steps that genuinely support your microbiome. You can learn more from Dr Suzanne Devkota by following her on Instagram, or by visiting the Cedars-Sinai Human Microbiome Research Institute and the Devkota Lab. Intro (00:00:00) The Microbiome Conversation (00:01:16) How Diversity Shapes Your Gut’s Health and Resilience (00:04:40) The First Three Years That Shape a Lifetime (00:08:09) What Microbiome Tests Can and Can’t Tell You (00:11:05) Probiotics, Prebiotics, Postbiotics (00:18:05) The Quiet Power of Short-Chain Fatty Acids (00:34:47) The Fiber Controversy and What People Get Wrong (00:47:58) How Daily Habits Quietly Reshape Your Microbiome (00:49:28) Antibiotics, Resetting, and Rebuilding Your Gut (00:52:07) How Early-Life Factors Imprint Your Gut for Decades (00:56:57) Why Chronic Inflammation and IBD Connect Back to the Microbiome (01:03:14) What We’re Learning About Colon Cancer and the Gut (01:16:13) The Future of Microbiome Science and Personalized Gut Care (01:27:45) This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Function Health Take charge of your health with advanced blood testing and personalised insights. Function Health offers a practical way to track key health markers such as cholesterol, blood sugar, and more. Learn more and join at functionhealth.com/simonhill for a $25 credit toward your membership. Only available to those living in the United States. Eight Sleep Upgrade your sleep with the Pod 5 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF for $400 off at eightsleep.com/theproof. Try it risk-free for 30 days, with worldwide shipping. Momentous My go-to supplement brand for protein and creatine is Momentous. Use code THEPROOF for up to 35% off your first order at livemomentous.com. Simon Hill, MSc, BSc (Hons) Creator of theproof.com Host of The Proof with Simon Hill Author of The Proof is in the Plants Subscribe & Connect: YouTube Apple Podcasts Spotify Instagram: @simonhill Twitter: @theproof Facebook: The Proof with Simon Hill

Published: 15 December 2025

In this episode I am joined by Mark Manson, author of The Subtle Art of Not Giving a Fck*, to talk about why so many of us build our lives around “shitty values” and what it takes to change. We discuss regret, shame and the stories we tell ourselves, and how taking responsibility without blaming yourself can transform the way you move through the world. Mark shares his counterintuitive values framework, why you actually need failure, uncertainty and rejection, and how contemplating your own mortality can help you decide what really deserves your limited time and energy. What We Cover Why “shitty values” are so alluring in early adulthood and how to recognise them in your own life The gap between your stated values and your lived behaviour, and why your actions tell the truth Responsibility versus fault, and how owning your choices creates agency after heartbreak and other setbacks People pleasing, approval seeking and the cost of caring too much what others think Why you should be willing to be disliked for something that matters and how this builds real trust How Mark thinks about “not giving a fuck” today and why it is really about better priorities, not apathy By the end of the episode you will have a more honest way to look at your own values, practical tools for choosing better problems, and a new appreciation for time, mortality and what is truly worth caring about. Intro (00:00:00) Rethinking Your Younger Self (00:02:05) What We Get Wrong About Values (00:05:36) Time, Maturity, and Self-Deception (00:08:09) The People Who Hold Up the Mirror (00:12:07) When Culture Points Us the Wrong Way (00:15:44) The Making of an Unlikely Bestseller (00:21:03) “I’m Enough”… But Am I Really? (00:38:38) The Five Counterintuitive Values (00:44:50) Responsibility Isn’t Blame (00:50:41) Living With Maybe (00:56:23) What ‘Not Giving a F*ck’ Actually Means (01:01:45) Seeing Life Through a Finite Lens (01:11:53) Why Boredom Still Matters (01:20:32) This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Function Health Take charge of your health with advanced blood testing and personalised insights. Function Health offers a practical way to track key health markers such as cholesterol, blood sugar, and more. Learn more and join at functionhealth.com/simonhill for a $25 credit toward your membership. Only available to those living in the United States. Shopify Shopify, the world's leading e-commerce platform, helps you turn browsers into buyers with the internet’s best-converting check out–up to 36% better compared to other leading e-commerce platforms. To boost your conversion rate, and grow your business, sign up for a one-dollar-per-month trial period at shopify.com/proof. Momentous My go-to supplement brand for protein and creatine is Momentous. Use code THEPROOF for up to 35% off your first order at livemomentous.com. AirBnB Right in the heart of the city, I’ve been hosting a hands-on Airbnb Experience at Little City Farm that’s all about plant diversity, gut health, and delicious food. For more information, or to find other experiences on your next trip, check out airbnb.com/experiences. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Simon Hill, MSc, BSc (Hons) Creator of theproof.com Host of The Proof with Simon Hill Author of The Proof is in the Plants Subscribe & Connect: YouTube Apple Podcasts Spotify Instagram: @simonhill Twitter: @theproof Facebook: The Proof with Simon Hill

Transcribed - Published: 8 December 2025

Dr Walter Willett has spent more than fifty years at the forefront of nutrition research, leading landmark studies that have shaped how we think about fat, carbohydrates, protein and chronic disease. In this episode, he joins me to untangle decades of confusion around saturated fat, seed oils, dairy, eggs, plant protein and more, and to explain what a truly healthy dietary pattern looks like when you consider both human health and planetary health. We explore how evidence from long term cohorts, clinical trials and global dietary patterns converges on a common theme, and what the Planetary Health Diet means in practical terms for you and your family. What We Cover How nutrition science has evolved and why the big picture is now clearer. Why the source of fat and carbohydrate matters more than the amount. The truth about seed oils, saturated fats, and dairy. Protein quality, plant to animal ratios, and what matters most for longevity. How diet affects cognitive ageing and dementia risk. The planetary health diet and how to eat for both people and planet. This is a nuanced, evidence based conversation with one of the most influential nutrition scientists of our time. I hope it helps you feel less confused and more empowered in the choices you make every day. The Fat Misconception of the 1970s (00:01:35) Media, Internet & Public Misinformation (00:05:36) Current Blind Spots & Future Predictions (00:09:55) Dietary Changes & Public Health Impact (00:13:47) Why the Mediterranean Diet Still Leads the Pack (00:18:02 How Nutrition Research Really Works (00:23:33) Fats, Oils, and the Myths That Won’t Die (00:32:57) Dairy: Health vs. Environmental Costs (00:45:35) Protein Intake & Healthy Aging (00:59:57) Fiber's Role in Health (01:19:59) Can Diet Protect Our Brain? (01:29:43) Food Choices and the Future of the Planet (01:40:48) This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Function Health Take charge of your health with advanced blood testing and personalised insights. Function Health offers a practical way to track key health markers such as cholesterol, blood sugar, and more. Learn more and join at functionhealth.com/simonhill for a $25 credit toward your membership. Only available to those living in the United States. LMNT Stay hydrated with LMNT. Get a free Sample Pack of LMNT’s most popular drink mix flavours with any purchase at DrinkLMNT.com/SIMON Find your favourite LMNT flavour, or share with a friend. And if you don’t like it? Full refund, no questions asked. IM8 With 92 nutrients, including Vitamin B12, Iodine, Selenium and Vitamin D, in highly absorbable forms, IM8 Daily Essentials is the perfect all-in-one daily multi-vitamin to ensure you meet your daily micronutrient needs. IM8 is offering an exclusive 10% off your first order with a free welcome kit when you enter the promo code SIMON at checkout on im8health.com Eight Sleep Upgrade your sleep with the Pod 5 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF for $400 off at eightsleep.com/theproof. Try it risk-free for 30 days, with worldwide shipping. SKIMS Upgrade your underwear drawer with SKIMS Mens. Soft, stretchy and built to stay in shape, they provide comfort and freedom of movement for training or everyday wear. Shop SKIMS Mens at SKIMS.com. Let them know we sent you! After you order, select "podcast" in the survey and choose The Proof from the dropdown. And if you’re looking for the perfect gifts this season - the SKIMS Holiday Shop is now open at SKIMS.com.

Transcribed - Published: 1 December 2025

Dr Jessica Knurick joins me to examine the systems influencing America’s health. We discuss the gap between individual choices and public health realities, the rise of MAHA, and why many proposed solutions fail to address the real drivers of chronic disease. Jessica breaks down regulation, subsidies and the role of corporations, the truth about food dyes and additives, and why SNAP remains essential for reducing food insecurity and improving health outcomes. What We Cover Jessica’s path into public health communication Individual behaviour versus systemic influence The MAHA movement and its limitations How regulation and subsidies shape our food environment What the evidence really shows about additives and food dyes Why SNAP matters and the consequences of defunding Policies that could genuinely improve child and adult health A timely and important conversation that brings clarity to a confusing and polarised nutrition landscape. You can connect with Dr Jessica Knurick on Instagram and TikTok, or visit her website and Substack to explore her work and evidence based insights on public health, nutrition and the systems shaping our wellbeing. Intro (00:00:00) The Unexpected Moment That Changed Everything (00:01:26) The Hidden Systems Behind Your Health (00:09:14) Agencies That Protect (or Fail) Public Health (00:18:11) The Dietary Guidelines You Thought You Knew (00:20:32) “Toxins,” Food Dyes, and the Real Story Behind Processed Foods (00:38:13) The Corporate Playbook Shaping America’s Health (00:47:56) A Program Millions Rely On… Yet Few Understand (00:57:38) The Hidden Battles Over Food Regulation (GRAS, Additives & More) (01:12:16) Science Funding, Misinformation, and Who Gets to Shape the Narrative (01:19:25) If You Want Better Health in America, Start Here (01:30:24) This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Function Health Take charge of your health with advanced blood testing and personalised insights. Function Health provides a practical solution to track key health markers such as cholesterol, blood sugar, and more. For the first 1,000 listeners, new members get a $100 credit when signing up. Head to functionhealth.com/simonhill to claim your credit. Only available to those living in the United States. Pique Tea Pique's Nandaka provides sustainable, all-day energy and makes you feel like you’re doing something good for your body! Go to Piquelife.com/simon and get 20% off sitewide FOR LIFE plus a complimentary exclusive holiday bundle. IM8 With 92 nutrients, including Vitamin B12, Iodine, Selenium and Vitamin D, in highly absorbable forms, IM8 Daily Essentials is the perfect all-in-one daily multi-vitamin to ensure you meet your daily micronutrient needs. IM8 is offering an exclusive 10% off your first order with a free welcome kit when you enter the promo code SIMON at checkout on im8health.com AirBnB Right in the heart of the city, I’ve been hosting a hands-on Airbnb Experience at Little City Farm that’s all about plant diversity, gut health, and delicious food. For more information, or to find other experiences on your next trip, check out airbnb.com/experiences. BetterHelp This is a paid advertisement from BetterHelp. This month, don’t wait to reach out. Whether you're checking in on a friend or reaching out to a therapist yourself, BetterHelp makes it easier to take that first step. Our listeners get 10% off their first month at BetterHelp.com/THEPROOF. Simon Hill, MSc, BSc (Hons) Creator of theproof.com Host of The Proof with Simon Hill Author of The Proof is in the Plants Subscribe & Connect: YouTube Apple Podcasts Spotify Instagram: @simonhill Twitter: @theproof Facebook: The Proof with Simon Hill

Transcribed - Published: 24 November 2025

Do women really need a completely different training plan to men, or has the "women are not small men" message been taken too far? I am joined by exercise scientist Dr Lauren Colenso-Semple to explore what the science actually shows about female physiology, menstrual cycles, menopause and strength training. We look at how women respond to exercise in real outcome studies, where hormone based claims come from, and how to build a simple, effective programme without getting lost in unnecessary complexity. What We Cover How similar men and women are in their basic responses to strength and endurance training The evidence on menstrual cycle based programming and why cycle syncing is not supported by muscle protein synthesis data Fasted vs fed training in women when total calories and protein are controlled Ageing, muscle, bone and why strength work and balance matter for fall prevention Protein targets in older adults and why training is the primary driver of gains Creatine, recovery and whether any supplements are uniquely helpful for women This episode will help you cut through confusing sex specific advice and build a training approach that is practical, sustainable and evidence based. If you want to hear more from Dr Lauren Colenso-Semple, you can explore her work on her website and connect with her on Instagram. Intro (00:00) Why Women Can’t Train Like Small Men (01:01) What Most Research Gets Wrong About Female Physiology (02:44) How Hormones Shape Training and Recovery (04:10) What the Data Really Says About Exercise for Women (06:00) Do Women Need Sex-Specific Training Plans? (10:26) Fasted vs Fed Workouts: Which Is Better for Women? (33:41) What Your Muscle Fibers Reveal About Performance (39:11) Can Strength Training Reverse Aging? (42:05) The Truth About Bone Density and Longevity (46:46) How Protein and Creatine Boost Results (01:05:05) The Most Effective Training Strategies for Women (01:15:15) This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Function Health Take charge of your health with advanced blood testing and personalised insights. Function Health provides a practical solution to track key health markers such as cholesterol, blood sugar, and more. For the first 1,000 listeners, new members get a $100 credit when signing up. Head to functionhealth.com/simonhill to claim your credit. Only available to those living in the United States. Momentous My go-to supplement brand for protein and creatine is Momentous. Use code theproof for up to 35% off your first order at livemomentous.com. SKIMS Upgrade your underwear drawer with SKIMS Mens. Soft, stretchy and built to stay in shape, they provide comfort and freedom of movement for training or everyday wear. Shop SKIMS Mens at SKIMS.com. Let them know we sent you! After you order, select "podcast" in the survey and choose The Proof from the dropdown. And if you’re looking for the perfect gifts this season - the SKIMS Holiday Shop is now open at SKIMS.com. IM8 With 92 nutrients, including Vitamin B12, Iodine, Selenium and Vitamin D, in highly absorbable forms, IM8 Daily Essentials is the perfect all-in-one daily multi-vitamin to ensure you meet your daily micronutrient needs. IM8 is offering an exclusive 10% off your first order with a free welcome kit when you enter the promo code SIMON at checkout on im8health.com Simon Hill, MSc, BSc (Hons) Creator of theproof.com Host of The Proof with Simon Hill Author of The Proof is in the Plants Subscribe & Connect: YouTube Apple Podcasts Spotify Instagram: @simonhill Twitter: @theproof Facebook: The Proof with Simon Hill

Transcribed - Published: 17 November 2025

Protein is one of the most talked-about nutrients, yet confusion remains about how much we need and which sources are best. I am joined by Dr Matthew Nagra to unpack the science on protein intake, plant versus animal sources, and how to build strength and longevity without compromising your health or the planet. What We Cover The evidence-based protein range for muscle and strength How plant and animal protein compare when total intake is matched Why training drives results more than protein alone New findings linking plant protein to lower chronic disease risk What the Andrea Glenn study reveals about protein density and heart health IGF-1 and mTOR myths and what the data really show The environmental and practical case for plant protein Protein plays a vital role in health, ageing and performance. This episode will help you cut through the noise and make confident, evidence-based choices. You can learn more from Dr Matthew Nagra by following him on Instagram and YouTube, or by visiting his website where he shares articles, resources and practical advice on nutrition and healthy living. Intro (00:00) The Protein Problem No One Can Agree On (00:57) Are You Eating Enough or Too Much Protein? (6:10) The Truth About Plant vs Animal Protein (16:16) What Really Drives Muscle Growth (21:57) The Surprising Science on Protein and Aging (24:42) Does Your Protein Choice Affect Disease Risk? (41:02) What Long-Term Studies Reveal About Health and Longevity (44:58) Is More Protein Always Better? (58:11) Why Nutrition Research Is So Confusing (01:07:10) The Hidden Cost of Animal Protein (01:13:35) Final Thoughts That Might Change How You Eat (01:43:53) This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Function Health Take charge of your health with advanced blood testing and personalised insights. Function Health provides a practical solution to track key health markers such as cholesterol, blood sugar, and more. For the first 1,000 listeners, new members get a $100 credit when signing up. Head to functionhealth.com/simonhill to claim your credit. Only available to those living in the United States. Eight Sleep  Upgrade your sleep with the Pod 5 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF for $700 off at eightsleep.com/theproof. Try it risk-free for 30 days, with worldwide shipping. Shopify Shopify, the world's leading e-commerce platform, helps you turn browsers into buyers with the internet’s best-converting check out–up to 36% better compared to other leading e-commerce platforms. To boost your conversion rate, and grow your business, sign up for a one-dollar-per-month trial period at shopify.com/proof. Momentous My go-to supplement brand for protein and creatine is Momentous. Use code theproof for up to 35% off your first order at livemomentous.com. AirBnB Right in the heart of the city, I’ve been hosting a hands-on Airbnb Experience at Little City Farm that’s all about plant diversity, gut health, and delicious food. For more information, or to find other experiences on your next trip, check out airbnb.com/experiences. Simon Hill, MSc, BSc (Hons) Creator of theproof.com Host of The Proof with Simon Hill Author of The Proof is in the Plants Subscribe & Connect: YouTube Apple Podcasts Spotify Instagram: @simonhill Twitter: @theproof Facebook: The Proof with Simon Hill

Transcribed - Published: 10 November 2025

I’m joined by author and coach Axel Schura to explore how hardship can lead to transformation. Axel shares his story of stage four cancer and the mindset shifts that inspired his new book “Maybe This Is Happening For You, Not To You”. We discuss fear, recovery, and how to find strength and meaning when life feels uncertain. What We Cover Shifting from “why me” to “what now” Facing fear with curiosity and compassion Tools for anxiety and rebuilding confidence Lessons from Viktor Frankl and the Chinese farmer story The power of belief and responsibility in healing A moving reminder that even in our hardest moments, there is always the potential for growth and meaning. Connect with Axel on Instagram, where he shares insights on mindset, personal growth, and emotional resilience. You can also visit axelschura.com to learn more about his work and get his new book “Maybe This Is Happening For You, Not To You” at axelschura.com/maybe. For more of Axel’s content, including his podcast and YouTube channel, head to his Linktree. How Axel Shura Turned Pain Into Purpose After Stage 4 Cancer Diagnosis (00:00) Confronting Death for the First Time (18:10) Reflecting on the Journey (25:11) Practical Advice for Dealing with Fear (41:03) Reframing Fear and Embracing Life (51:10) The Power of Feedback and Facing Judgment (55:34) Mini Risks and Overcoming Isolation (01:07:25) The Importance of Belief and Vision (01:12:30) The Chinese Farmer Story: Embracing Uncertainty (01:17:28) Radical Responsibility and Viktor Frankl's Influence (01:24:46) Concluding Thoughts and Reflections (01:29:49) This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Function Health Take charge of your health with advanced blood testing and personalised insights. Function Health provides a practical solution to track key health markers such as cholesterol, blood sugar, and more. For the first 1,000 listeners, new members get a $100 credit when signing up. Head to functionhealth.com/simonhill to claim your credit. Only available to those living in the United States Momentous My go-to supplement brand for protein and creatine is Momentous. Use code LIVINGPROOF for up to 35% off your first order at livemomentous.com. LMNT Stay hydrated with LMNT. Get a free Sample Pack of LMNT’s most popular drink mix flavours with any purchase at DrinkLMNT.com/SIMON Find your favourite LMNT flavour, or share with a friend. And if you don’t like it? Full refund, no questions asked. Eight Sleep Upgrade your sleep with the Pod 5 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF for $350 off at eightsleep.com/theproof. Try it risk-free for 30 days, with worldwide shipping. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Simon Hill, MSc, BSc (Hons) Creator of theproof.com Host of The Proof with Simon Hill Author of The Proof is in the Plants Subscribe & Connect: YouTube Apple Podcasts Spotify Instagram: @simonhill Twitter: @theproof Facebook: The Proof with Simon Hill Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.

Transcribed - Published: 3 November 2025

Dr Dawn Mussallem’s life has defied all odds. After surviving stage 4 cancer, severe heart failure, and a heart transplant, she ran a marathon just one year later. In this conversation, I sit down with Dawn as she shares what she’s learned about resilience, faith, and the science of healing. We explore the mindset behind recovery, how food and lifestyle can prevent disease, and the lessons from decades of cancer research and clinical care. It’s a deeply human discussion on what it means to live with intention, vitality, and compassion. What We Cover Mindset, purpose, and finding meaning in adversity Plant-based diets for cancer prevention and metabolic health Fasting, sleep, and stress management Supplements, Omega-3s, and key nutrients to focus on Myths about seed oils, soy, and grains GLP-1 medications, muscle preservation, and weight management Why connection, joy, and movement are central to longevity A testament to the strength of the human spirit—and a guide to living better, not just longer. Connect with Dr Dawn Mussallem on Instagram or LinkedIn to follow her work in lifestyle medicine, cancer recovery, and longevity research. This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Function Health Take charge of your health with advanced blood testing and personalised insights. Function Health provides a practical solution to track key health markers such as cholesterol, blood sugar, and more. For the first 1,000 listeners, new members get a $100 credit when signing up. Head to functionhealth.com/simonhill to claim your credit. Only available to those living in the United States. Momentous My go-to supplement brand for protein and creatine is Momentous. Use code LIVINGPROOF for up to 35% off your first order at livemomentous.com. AirBnB Right in the heart of the city, I’ve been hosting a hands-on Airbnb Experience at Little City Farm that’s all about plant diversity, gut health, and delicious food. For more information, or to find other experiences on your next trip, check out airbnb.com/experiences. Pique Tea Pique's Nandaka provides sustainable, all-day energy and makes you feel like you’re doing something good for your body! Try Pique and get 20% off plus a FREE starter kit when you shop exclusively at Piquelife.com/simon. Eight Sleep Upgrade your sleep with the Pod 5 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF for $350 off at eightsleep.com/theproof. Try it risk-free for 30 days, with worldwide shipping.

Transcribed - Published: 27 October 2025

In this episode, I continue my conversation with Dr Raymond Townsend, Professor of Medicine at the University of Pennsylvania. We explore how to optimise and treat high blood pressure through lifestyle, medication and a deeper understanding of the latest clinical evidence. Dr Townsend explains how much risk reduction comes from lowering blood pressure, what the newest AHA/ACC guidelines recommend, and how diet, exercise and sleep all play a role in protecting your arteries, kidneys and brain. What We Cover Why lowering blood pressure matters The latest hypertension guidelines When to start medication Key lifestyle interventions for long-term health Common myths about salt, diet and protein New therapies and what’s on the horizon Blood pressure is not just a number — it is a reflection of your overall health. This episode provides a practical guide to lowering it safely and effectively. Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family. This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Function Health Take charge of your health with advanced blood testing and personalised insights. Function Health provides a practical solution to track key health markers such as cholesterol, blood sugar, and more. For the first 1,000 listeners, new members get a $100 credit when signing up. Head to functionhealth.com/simonhill to claim your credit. Only available to those living in the United States. LMNT Stay hydrated with LMNT. Get a free Sample Pack of LMNT’s most popular drink mix flavours with any purchase at DrinkLMNT.com/SIMON Find your favourite LMNT flavour, or share with a friend. And if you don’t like it? Full refund, no questions asked. Momentous My go-to supplement brand for protein and creatine is Momentous. Use code LIVINGPROOF for up to 35% off your first order at livemomentous.com. Eight Sleep Upgrade your sleep with the Pod 5 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF for $350 off at eightsleep.com/theproof. Try it risk-free for 30 days, with worldwide shipping. BetterHelp This is a paid advertisement from BetterHelp. This World Mental Health Day, we’re celebrating the therapists who’ve helped millions of people take a step forward. If you’re ready to find the right therapist for you, BetterHelp can help you start that journey. Our listeners get 10% off their first month at BetterHelp.com/THEPROOF. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Simon Hill, MSc, BSc (Hons) Creator of theproof.com Host of The Proof with Simon Hill Author of The Proof is in the Plants Subscribe & Connect: YouTube Apple Podcasts Spotify Instagram: @simonhill Twitter: @theproof Facebook: The Proof with Simon Hill

Transcribed - Published: 21 October 2025

In this episode, I am joined by Dr Raymond Townsend, Director of the Hypertension Programme at the University of Pennsylvania. We discuss what drives high blood pressure, how it affects the body, and practical steps to protect your heart, kidneys and brain. Dr Townsend explains how genetics, age, lifestyle and arterial stiffness contribute to hypertension, how to measure blood pressure correctly, and why early action and empathy make such a difference in long-term outcomes. What We Cover Understanding blood pressure readings How hypertension harms the heart, brain and kidneys Lifestyle and genetic contributors Why arterial stiffness increases with age The right way to measure blood pressure When lifestyle changes or medication are needed High blood pressure is preventable, manageable and worth your attention long before symptoms appear. Introduction (00:00) Key Takeaways from 40 Years in Hypertension (01:14) What does “hypertension” actually mean? (08:54) How Blood Pressure Works: Systolic vs diastolic explained simply (12:10) Why High BP Is Dangerous: Heart, brain & kidney damage mechanisms (14:35) What Are the Main Causes of Hypertension (28:03) The Aging Process and Blood Pressure (33:50) Can arteries stay flexible and young through exercise and recovery (37:46) Why even young adults should care about blood pressure control (40:01) Dementia and Blood Pressure: The Long-Term Connection (41:16) Awareness and Diagnosis of Hypertension (43:52) Measuring Blood Pressure Correctly (47:10) When to Intervene: Thresholds and Treatments (56:52) Primary vs. Secondary Prevention (01:01:56) This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Function Health Take charge of your health with advanced blood testing and personalised insights. Function Health provides a practical solution to track key health markers such as cholesterol, blood sugar, and more. For the first 1,000 listeners, new members get a $100 credit when signing up. Head to functionhealth.com/simonhill to claim your credit. Only available to those living in the United States. Eight Sleep Upgrade your sleep with the Pod 5 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF for $350 off at eightsleep.com/theproof. Try it risk-free for 30 days, with worldwide shipping. IM8 With 92 nutrients, including Vitamin B12, Iodine, Selenium and Vitamin D, in highly absorbable forms, IM8 Daily Essentials is the perfect all-in-one daily multi-vitamin to ensure you meet your daily micronutrient needs. IM8 is offering an exclusive 10% off your first order with a free welcome kit when you enter the promo code SIMON at checkout on im8health.com Shopify Shopify, the world's leading e-commerce platform, helps you turn browsers into buyers with the internet’s best-converting check out–up to 36% better compared to other leading e-commerce platforms. To boost your conversion rate, and grow your business, sign up for a one-dollar-per-month trial period at shopify.com/proof. AirBnB Right in the heart of the city, I’ve been hosting a hands-on Airbnb Experience at Little City Farm that’s all about plant diversity, gut health, and delicious food. For more information, or to find other experiences on your next trip, check out airbnb.com/experiences. SKIMS Upgrade your underwear drawer with SKIMS Mens. Soft, stretchy and built to stay in shape, they provide comfort and freedom of movement for training or everyday wear. Shop SKIMS Mens at SKIMS.com. Let them know we sent you! After you order, select "podcast" in the survey and choose The Proof from the dropdown.

Transcribed - Published: 13 October 2025

In this episode I am joined by Dr Iñigo San Millán, exercise physiologist, researcher, and coach to Tour de France champion Tadej Pogačar. His work places lactate at the centre of human health, showing it as a fuel and biomarker rather than a waste product. We discuss how lactate offers a new lens on mitochondrial health, what Zone 2 training really achieves, and why these insights apply to both elite athletes and anyone seeking longevity. What We Cover Lactate myths and the truth about its role in energy Differences between athletic and diseased lactate profiles Zone 2 training and mitochondrial health Balancing training methods for metabolic flexibility Diet, lactate, and critiques of Zone 2 This conversation shows why understanding lactate could be key to improving performance, preventing disease, and ageing well. You can connect with Dr Iñigo San Millán on Instagram and Twitter, where he shares insights on exercise physiology, metabolism, and performance. Follow along to learn more about his research and practical applications for both athletes and everyday health. Understanding Lactate as a Biomarker and Signalling Molecule (00:00) Historical Misconceptions About Lactate and Fatigue (04:03) How the Body Uses Lactate as a Fuel Source (06:09) Lactate in Health, Metabolic Function, and Disease (10:25) Exercise, Lactate Dynamics, and Energy Balance (16:39) What Research Reveals About Lactate and Mitochondrial Function (19:03) Exercise Prescription and Training Zones Explained (26:20) High-Intensity Exercise: What Happens to Lactate Levels? (37:87) VO₂ Max, Mitochondria, and Aerobic Fitness (45:02) Supporting Mitochondrial Function for Disease Prevention (48:37) Designing Exercise Programmes for Longevity and Healthspan (51:19) Resistance Training and Its Impact on Metabolic Health (1:00:10) How Diet and Exercise Influence Mitochondrial Function (01:04:42) Is Zone Two Training Really the Key to Endurance? (01:10:39) Final Reflections on Lactate, Training, and Metabolic Adaptation (01:19:47) This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Function Health Take charge of your health with advanced blood testing and personalised insights. Function Health provides a practical solution to track key health markers such as cholesterol, blood sugar, and more. For the first 1,000 listeners, new members get a $100 credit when signing up. Head to functionhealth.com/simonhill to claim your credit. Only available to those living in the United States. Momentous My go-to supplement brand for protein and creatine is Momentous. Use code LIVINGPROOF for up to 35% off your first order at livemomentous.com. IM8 With 92 nutrients, including Vitamin B12, Iodine, Selenium and Vitamin D, in highly absorbable forms, IM8 Daily Essentials is the perfect all-in-one daily multi-vitamin to ensure you meet your daily micronutrient needs. IM8 is offering an exclusive 10% off your first order with a free welcome kit when you enter the promo code SIMON at checkout on im8health.com Eight Sleep Upgrade your sleep with the Pod 5 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF for $350 off at eightsleep.com/theproof. Try it risk-free for 30 days, with worldwide shipping. Simon Hill, MSc, BSc (Hons) Creator of theproof.com Host of The Proof with Simon Hill Author of The Proof is in the Plants Subscribe & Connect: YouTube Apple Podcasts Spotify Instagram: @simonhill Twitter: @theproof Facebook: The Proof with Simon Hill

Transcribed - Published: 6 October 2025

What happens when you suddenly lose hearing in one ear? In this solo episode, I share my experience with sudden sensorineural hearing loss, from the moment it struck to the treatments I pursued and the outcome. Along the way I explain what the evidence says about oral steroids, intratympanic injections, hyperbaric oxygen therapy, and more, while also reflecting on the emotional side of navigating this health scare. What I Cover The onset and diagnosis of sudden hearing loss Oral steroids, intratympanic injections, and antivirals Hyperbaric oxygen therapy and recovery odds Emotional challenges and mindset shifts Key take-home lessons if this happens to you This is a personal and practical episode that may one day help you or someone you know act quickly in a critical moment. What Happened When I Lost Hearing in One Ear? (00:00) How Is Sudden Hearing Loss Diagnosed? (09:19) What Causes Sudden Hearing Loss? (14:50) Sudden Hearing Loss Treatment Protocol Explained (21:06) Do Hyperbaric Oxygen & Lifestyle Help? (25:35) How Fast Can Hearing Return? (30:06) Key Lessons for Recovery (38:52) Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family. This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Function Health Take charge of your health with advanced blood testing and personalised insights. Function Health provides a practical solution to track key health markers such as cholesterol, blood sugar, and more. For the first 1,000 listeners, new members get a $100 credit when signing up. Head to functionhealth.com/simonhill to claim your credit. Only available to those living in the United States. Eight Sleep Upgrade your sleep with the Pod 5 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF for $350 off at eightsleep.com/theproof. Try it risk-free for 30 days, with worldwide shipping. Pique Tea Pique's Nandaka provides sustainable, all-day energy and makes you feel like you’re doing something good for your body! Try Pique and get 20% off plus a FREE starter kit when you shop exclusively at Piquelife.com/simon. Momentous My go-to supplement brand for protein and creatine is Momentous. Use code LIVINGPROOF for up to 35% off your first order at livemomentous.com Bragg Bragg Organic Apple Cider Vinegar is raw, unfiltered, and naturally fermented with 100% organic apples, always with the live “Mother” in every bottle. Get 20% off your first order at bragg.com with promo code SIMON. AirBnB Right in the heart of the city, I’ve been hosting a hands-on Airbnb Experience at Little City Farm that’s all about plant diversity, gut health, and delicious food. For more information, or to find other experiences on your next trip, check out airbnb.com/experiences. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Simon Hill, MSc, BSc (Hons) Creator of theproof.com Host of The Proof with Simon Hill Author of The Proof is in the Plants Subscribe & Connect: YouTube Apple Podcasts Spotify Instagram: @simonhill Twitter: @theproof Facebook: The Proof with Simon Hill Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.

Transcribed - Published: 29 September 2025

In this episode, I’m joined by Dr Jed Fahey, nutritional biochemist who pioneered sulforaphane research at Johns Hopkins, and Doug Evans, author of The Sprout Book. We discuss why broccoli sprouts are one of the most powerful foods you can grow at home and how to use them safely and effectively. Jed explains the science of sulforaphane and the strongest clinical evidence so far, while Doug shares practical advice for sprouting at home, seed safety, and making sprouts part of everyday meals. What We Cover Sulforaphane and its unique effects in the body The most promising human trials How much broccoli sprout or supplement is useful Sprouts compared with supplements and mature vegetables Food safety and storage How to sprout easily at home Sprouts are simple, affordable, and surprisingly powerful, and this episode shows you how to get started. You can connect with Doug through Instagram, where he shares insights on health, wellness, and sprouting. Explore more of his work at The Sprouting Company, and follow The Sprouting Company on Instagram for practical tips and inspiration to bring sprouting into your daily life. If you want to hear more from Dr Jed Fahey, you can access his website and connect with him on Twitter. He has lots of exciting things in the works. Why Sprouts Stayed a Garnish: History, Culture & the Profit Problem (00:00:00) Are Vegetables Less Nutritious Today? (00:10:16) Can Sulforaphane and Sprouts Help Prevent Disease? (00:25:09) Broccoli vs Sprouts: How Sulforaphane Is Formed and Absorbed (00:40:26) How Does Sulforaphane Protect the Body? (00:49:01) Can Broccoli Sprouts Prevent Cancer, and How Much Do We Need? (00:57:08) Can You Trust Sprout Supplements? (01:04:14) Sulforaphane’s Role in Viruses, Pollution, Autism & Parkinson’s (01:13:30) Sprouts for Short-Term vs Long-Term Health (01:26:54) Making Sprouts Accessible For Everyone (01:37:30) How Do You Grow Sprouts Safely at Home? (01:52:58) Are Homegrown Sprouts Safe From Contamination? (01:58:47) Science Meets Mission: Sprouts, Purpose, and Prevention (02:08:51) This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Function Health Take charge of your health with advanced blood testing and personalised insights. Function Health provides a practical solution to track key health markers such as cholesterol, blood sugar, and more. For the first 1,000 listeners, new members get a $100 credit when signing up. Head to functionhealth.com/simonhill to claim your credit. Only available to those living in the United States. Eight Sleep Upgrade your sleep with the Pod 5 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF for $350 off at eightsleep.com/theproof. Try it risk-free for 30 days, with worldwide shipping. LMNT Stay hydrated with LMNT. Get a free Sample Pack of LMNT’s most popular drink mix flavours with any purchase at DrinkLMNT.com/SIMON Find your favourite LMNT flavour, or share with a friend. And if you don’t like it? Full refund, no questions asked. Momentous My go-to supplement brand for protein and creatine is Momentous. Use code LIVINGPROOF for up to 35% off your first order at livemomentous.com Simon Hill, MSc, BSc (Hons) Creator of theproof.com Host of The Proof with Simon Hill Author of The Proof is in the Plants Subscribe & Connect: YouTube Apple Podcasts Spotify Instagram: @simonhill Twitter: @theproof Facebook: The Proof with Simon Hill

Transcribed - Published: 22 September 2025

In this episode, I’m joined by Hannah Ritchie, senior researcher at Our World in Data and author of Clearing the Air. We dive into the data behind climate change, exploring what’s driving it, how solutions are developing, and why optimism is not misplaced. Hannah breaks down the role of food, energy, and industry in emissions, explains where media narratives can create “climate whiplash,” and shares why imperfect solutions still move us in the right direction. What We Cover Food, diet, and agricultural emissions Renewable energy vs fossil fuels Electric vehicles and battery concerns Aviation’s role in climate change AI’s growing energy footprint Individual choices vs systemic change This conversation is a reminder that climate change is solvable, and that progress is already underway. You can connect with Hannah Ritchie on Bluesky and through her newsletter, Sustainability by Numbers, or explore her work at hannahritchie.com and Our World in Data. Why We Get Confused About Climate Solutions (00:00:00) The Real Barriers: Cost, Fear, and Trust (00:10:12) Climate Change Impacts on Heat, Health, and Food (00:19:01) Can Plant-Based Diets Meet Nutrition Needs? (00:36:56) Which Food Swaps Most Reduce Emissions? (00:43:02) Is Regenerative Beef Better for the Climate? (00:50:18) Do Plant-Based Meats Help the Environment? (00:57:49) Why We Still Rely on Fossil Fuels (01:04:17) Do Wealthy Countries Owe the World Clean Energy? (01:17:39) AI and Climate: Problem or Solution? (01:24:28) Electric vs Petrol Cars: Which Is Better? (01:29:09) Can Technology Decarbonize Aviation? (01:42:18) Who’s Responsible: Individuals or Government? (01:51:02) Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family. This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Function Health Take charge of your health with advanced blood testing and personalised insights. Function Health provides a practical solution to track key health markers such as cholesterol, blood sugar, and more. For the first 1,000 listeners, new members get a $100 credit when signing up. Head to functionhealth.com/simonhill to claim your credit. Only available to those living in the United States. AirBnB Right in the heart of the city, I’ve been hosting a hands-on Airbnb Experience at Little City Farm that’s all about plant diversity, gut health, and delicious food. For more information, or to find other experiences on your next trip, check out airbnb.com/experiences. Momentous My go-to supplement brand for protein and creatine is Momentous. Use code LIVINGPROOF for up to 35% off your first order at livemomentous.com Bragg Bragg Organic Apple Cider Vinegar is raw, unfiltered, and naturally fermented with 100% organic apples, always with the live “Mother” in every bottle. Get 20% off your first order at bragg.com with promo code SIMON. IM8 With 92 nutrients, including Vitamin B12, Iodine, Selenium and Vitamin D, in highly absorbable forms, IM8 Daily Essentials is the perfect all-in-one daily multi-vitamin to ensure you meet your daily micronutrient needs. IM8 is offering an exclusive 10% off your first order with a free welcome kit when you enter the promo code SIMON at checkout on im8health.com Simon Hill, MSc, BSc (Hons) Creator of theproof.com Host of The Proof with Simon Hill Author of The Proof is in the Plants Subscribe & Connect: YouTube Apple Podcasts Spotify Instagram: @simonhill Twitter: @theproof Facebook: The Proof with Simon Hill

Transcribed - Published: 15 September 2025

What does balance really mean for diet, and why is nuance so often lost in nutrition debates? In this episode, I sit down again with Dr David Katz to explore diet quality, ultra-processed foods, supplements, and the broader links between human and planetary health. In this episode, we cover: Why balance is the key to diet quality Beef, ethics, and planetary health Keto and carnivore, the rise of anecdotes online Ultra-processed foods and why they drive overeating Supplements, evidence, controversies, and David’s personal approach A grounded and insightful discussion on how to cut through the noise and focus on what really matters for long-term health. You can connect with Dr David Katz on LinkedIn, Facebook, and X (Twitter). To learn more about his work, visit davidkatzmd.com, explore Diet ID, and discover the True Health Initiative. The Critical Role of Diet in Chronic Disease and Longevity (00:00:00) What Does a High-Quality Diet Actually Mean? (00:05:03) Why Balance Is the Essence of Diet Quality (00:12:07) What Does a Balanced Diet Look Like in Practice? (00:20:30) Why Should We Eat Less Beef? (00:23:44) Plant-Based vs Omnivore Diets: Which Is Healthier? (00:30:25) Are Keto and Carnivore Diets Healthy Long-Term? (00:38:49) How Can We Fight Nutrition Misinformation? (00:45:56) How Ultra-Processed Foods Hijack Appetite and Drive Overeating (01:00:12) How Do We Tell Good vs Bad Ultra-Processed Foods? (01:10:32) Can Reformulated Ultra-Processed Foods Improve Public Health? (01:19:04) How Measuring Diet Quality Could Transform Public Health (01:26:50) How Diet ID Measures and Improves Diet Quality (01:31:15) Do Supplements Work and Which Ones Are Worth Taking? (01:43:11) Lessons From 40 Years in Medicine and Public Health (01:52:14) Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family. This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Function Health Take charge of your health with advanced blood testing and personalised insights. Function Health provides a practical solution to track key health markers such as cholesterol, blood sugar, and more. For the first 1,000 listeners, new members get a $100 credit when signing up. Head to functionhealth.com/simonhill to claim your credit. Only available to those living in the United States. Shopify Shopify, the world's leading e-commerce platform, helps you turn browsers into buyers with the internet’s best-converting check out–up to 36% better compared to other leading e-commerce platforms. To boost your conversion rate, and grow your business, sign up for a one-dollar-per-month trial period at shopify.com/proof. Eight Sleep Upgrade your sleep with the Pod 5 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF for $350 off at eightsleep.com/theproof. Try it risk-free for 30 days, with worldwide shipping. Simon Hill, MSc, BSc (Hons) Creator of theproof.com Host of The Proof with Simon Hill Author of The Proof is in the Plants Subscribe & Connect: YouTube Apple Podcasts Spotify Instagram: @simonhill Twitter: @theproof Facebook: The Proof with Simon Hill Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.

Transcribed - Published: 8 September 2025

In this episode, I’m joined by Dr Tom Dayspring and Dr Dan Soffer for a comprehensive look at lipid-lowering therapy. We unpack the science behind statins, ezetimibe, PCSK9 inhibitors, fibrates, and newer agents like bempedoic acid, asking what really works, who should take them, and how early treatment might prevent disease. From guideline thresholds to real-world decision making, historical trials to future therapies, this conversation offers clarity on one of the most important areas in cardiovascular prevention. In this episode, we cover: What lipid-lowering therapy actually is Statins, ezetimibe, fibrates, and PCSK9 inhibitors How these drugs work and who benefits most Absolute vs relative risk reduction explained Guidelines vs clinical practice Lipoprotein(a) and new therapies on the horizon A detailed yet practical discussion to help you cut through the noise and make sense of lipid-lowering therapies. Intro: What Are Cholesterol-Lowering Drugs and How Do They Work? (00:00:00) How Do Cholesterol-Lowering Medications Lower Heart Risk? (00:05:00) Who Should Start Statins or Other Cholesterol Drugs? (00:09:29) Landmark Cholesterol Trials That Changed Heart Disease Treatment (00:22:54) Do Fibrates Still Matter for High Triglycerides? (00:36:27) Ezetimibe & PCSK9 Inhibitors: Do They Add Benefits Beyond Statins? (00:42:30) CLEAR Outcomes Trial: What It Means for Statin-Intolerant Patients (00:52:02) Bempedoic Acid vs Statins: Effectiveness, Side Effects & Cost (00:53:45) What Do Statin Trials Really Show? Heart Attacks, Death & Risk Reduction (01:00:35) When to Use Low vs High-Intensity Statins (and Add Ezetimibe) (01:10:52) Hydrophilic vs Lipophilic Statins: What’s the Difference? (01:14:17) Do Statins Affect the Brain or Your Body’s Cholesterol? (01:19:03) PCSK9 Therapies Explained: Antibodies, siRNA, Oral Drugs & Gene Editing (01:24:28) What’s the Best Combination Therapy After Statins? (01:30:33) LDL Guidelines Explained: Thresholds vs Goals (01:32:49) The Most Up-to-Date Cholesterol Guidelines (2025) (01:40:25) This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Fireflies Stay focused and let Fireflies handle the notes. From transcriptions and summaries to real-time voice commands, Fireflies turns your meetings into actionable insights, seamlessly integrating with Zoom, Google Meet, Slack, and more. Sign up for a yearly plan and get two months FREE at fireflies.ai/theproof. Bragg Bragg Organic Apple Cider Vinegar is raw, unfiltered, and naturally fermented with 100% organic apples, always with the live “Mother” in every bottle. Get 20% off your first order at bragg.com with promo code SIMON. IM8 With 92 nutrients, including Vitamin B12, Iodine, Selenium and Vitamin D, in highly absorbable forms, IM8 Daily Essentials is the perfect all-in-one daily multi-vitamin to ensure you meet your daily micronutrient needs. IM8 is offering an exclusive 10% off your first order with a free welcome kit when you enter the promo code SIMON at checkout on im8health.com WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Simon Hill, MSc, BSc (Hons) Creator of theproof.com Host of The Proof with Simon Hill Author of The Proof is in the Plants Subscribe & Connect: YouTube Apple Podcasts Spotify Instagram: @simonhill Twitter: @theproof Facebook: The Proof with Simon Hill

Transcribed - Published: 1 September 2025

In today’s episode, I sit down with Professor Susan Davis, an endocrinologist and one of the world’s foremost experts on hormones in women’s health. We explore the role of testosterone in women, separating fact from fiction, and tackling the common myths that circulate online and in the media. Susan shares what decades of research actually show about testosterone therapy, its benefits, limitations, and safety, and why participation in clinical trials is essential for moving the science forward. What We Cover Why testosterone is not just a male hormone How levels change throughout a woman’s life Common myths about testosterone therapy and the truth behind them The link between testosterone, libido, and sexual function Evidence for and against claims around mood, muscle, and wellbeing Side effects and safety considerations at female-appropriate doses Compounded hormones compared with pharmaceutical formulations The biggest gaps in research and where the science needs to go next This episode offers an evidence-based look at testosterone in women, helping you cut through the noise and focus on what the science really says. Intro: (00:00) Which Testosterone Claims Are True And Which Are False? (05:42) What Does Testosterone Do In A Woman’s Body? (12:09) How Do Testosterone Levels Change Across A Woman’s Life? (15:12) How Can Women Measure Testosterone Accurately? (20:24) What Is The Relationship Between Testosterone And Low Libido? (27:32) What Are The Outcomes And Dosing Of Testosterone Therapy? (32:24) Which Delivery Methods Work Best For Testosterone Therapy? (39:22) Does Testosterone Improve Muscle Mass Or Mood? (43:46) What Are The Safety Considerations For Testosterone Therapy? (47:15) Compounded Versus Pharmaceutical Testosterone Therapy (52:02) Research Gaps In Testosterone And How Women Can Help (58:09) This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Pique Tea Pique's Nandaka provides sustainable, all-day energy and makes you feel like you’re doing something good for your body! Try Pique and get 20% off plus a FREE starter kit when you shop exclusively at Piquelife.com/simon. Eight Sleep Upgrade your sleep with the Pod 5 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF for $350 off at eightsleep.com/theproof. Try it risk-free for 30 days, with worldwide shipping. Fireflies Stay focused and let Fireflies handle the notes. From transcriptions and summaries to real-time voice commands, Fireflies turns your meetings into actionable insights, seamlessly integrating with Zoom, Google Meet, Slack, and more. Sign up for a yearly plan and get two months FREE at fireflies.ai/theproof. Function Health Take charge of your health with advanced blood testing and personalised insights. Function Health provides a practical solution to track key health markers such as cholesterol, blood sugar, and more. For the first 1,000 listeners, new members get a $100 credit when signing up. Head to functionhealth.com/simonhill to claim your credit. Only available to those living in the United States. LMNT Stay hydrated with LMNT. Get a free Sample Pack of LMNT’s most popular drink mix flavours with any purchase at DrinkLMNT.com/SIMON Find your favourite LMNT flavour, or share with a friend. And if you don’t like it? Full refund, no questions asked. Simon Hill, MSc, BSc (Hons) Creator of theproof.com Host of The Proof with Simon Hill Author of The Proof is in the Plants Subscribe & Connect: YouTube Apple Podcasts Spotify Instagram: @simonhill Twitter: @theproof Facebook: The Proof with Simon Hill

Transcribed - Published: 25 August 2025

High blood pressure, often called the silent killer, is the most deadly modifiable risk factor worldwide. In this solo episode, I break down the latest European and American blood pressure guidelines into a simple, actionable framework. I explain what blood pressure is, why it matters, how to measure it correctly at home, and the lifestyle changes that can lower it as effectively as first-line medication. Whether you want to prevent hypertension, manage it, or simply understand your numbers, this episode could change, and even save, your life. Introduction: Understanding High Blood Pressure & Its Dangers (00:00) How Common is Hypertension? (05:53) Why Hypertension Has No Symptoms: The "Silent Killer" Explained (07:52) Blood Pressure Numbers Explained: What Do Your Readings Mean? (10:00) How to Measure Blood Pressure Accurately (12:34) Getting an Accurate Reading at the Doctor's Office (14:14) 5 Steps to Accurate Home Blood Pressure Monitoring (16:17) Lifestyle Changes vs. Medication for High Blood Pressure (19:14) 6 Lifestyle Strategies to Lower Blood Pressure Naturally (24:29) DASH Diet for Hypertension & Other BP-Lowering Foods (26:45) What’s the Best Sodium and Potassium Balance for Heart Health? (30:37) How Does Your Gut Microbiome Affect Blood Pressure? (35:15) What’s the Best Exercise for Hypertension? (37:40) Does Alcohol Affect Your Blood Pressure? (43:19) How Coffee & Sugary Beverages Affect Your Blood Pressure (47:50) Smoking, Stress, and Other Lifestyle Factors Affecting BP (49:42) Your Action Plan for Healthy Blood Pressure (51:02) Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family. This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Bragg Bragg Organic Apple Cider Vinegar is raw, unfiltered, and naturally fermented with 100% organic apples, always with the live “Mother” in every bottle. Get 20% off your first order at bragg.com with promo code SIMON. Momentous My go-to supplement brand for protein and creatine is Momentous. Use code LIVINGPROOF for up to 35% off your first order at livemomentous.com IM8 With 92 nutrients, including Vitamin B12, Iodine, Selenium and Vitamin D, in highly absorbable forms, IM8 Daily Essentials is the perfect all-in-one daily multi-vitamin to ensure you meet your daily micronutrient needs. IM8 is offering an exclusive 10% off your first order with a free welcome kit when you enter the promo code SIMON at checkout on im8health.com AirBnB Right in the heart of the city, I’ve been hosting a hands-on Airbnb Experience at Little City Farm that’s all about plant diversity, gut health, and delicious food. For more information, or to find other experiences on your next trip, check out airbnb.com/experiences. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Simon Hill, MSc, BSc (Hons) Creator of theproof.com Host of The Proof with Simon Hill Author of The Proof is in the Plants Subscribe & Connect: YouTube Apple Podcasts Spotify Instagram: @simonhill Twitter: @theproof Facebook: The Proof with Simon Hill Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.

Transcribed - Published: 19 August 2025

In this masterclass, I break down the science of gut health and how to use it to your advantage. You’ll learn the different types of fiber, the benefits of fermentation, and how your gut microbes influence digestion, immunity, and even mood. Plus, I share practical tips for increasing fiber without discomfort and simple ways to nurture a thriving microbiome. Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family. This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Function Health Track, optimise, and thrive with Function Health. Access 100+ lab tests – five times more than a typical physical – including ApoB and LP(a), no doctor approval needed. Get science-backed insights and track your results over time. Join me on the path to next-level health optimisation at functionhealth.com/simonhill. Only available to those living in the United States. Shopify Shopify, the world's leading e-commerce platform, helps you turn browsers into buyers with the internet’s best-converting check out–up to 36% better compared to other leading e-commerce platforms. To boost your conversion rate, and grow your business, sign up for a one-dollar-per-month trial period at shopify.com/proof. Eight Sleep Upgrade your sleep with the Pod 5 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF for $350 off at eightsleep.com/theproof. Try it risk-free for 30 days, with worldwide shipping. Fireflies Stay focused and let Fireflies handle the notes. From transcriptions and summaries to real-time voice commands, Fireflies turns your meetings into actionable insights, seamlessly integrating with Zoom, Google Meet, Slack, and more. Sign up for a yearly plan and get two months FREE at fireflies.ai/theproof. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Simon Hill, MSc, BSc (Hons) Creator of theproof.com Host of The Proof with Simon Hill Author of The Proof is in the Plants Subscribe & Connect: YouTube Apple Podcasts Spotify Instagram: @simonhill Twitter: @theproof Facebook: The Proof with Simon Hill Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.

Transcribed - Published: 11 August 2025

In this solo episode, I break down the most common supplements, including vitamin D, omega-3s, creatine, B12, and probiotics. I share what the science really says about their effectiveness, safety, and who actually needs them. I also explain how I use blood test data to make smarter supplement decisions and why testing beats guessing every time. What I cover: Vitamin D and optimal levels Who really needs omega-3s Creatine’s brain and performance benefits Iron, B12, and nutrients to monitor on a plant-based diet Magnesium and why most people are low How to think about multivitamins and “daily essentials” The role of testing in personalising supplementation Supplements I take and why Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family. This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. AirBnB Right in the heart of the city, I’ve been hosting a hands-on Airbnb Experience at Little City Farm that’s all about plant diversity, gut health, and delicious food. For more information, or to find other experiences on your next trip, check out airbnb.com/experiences. Momentous My go-to supplement brand for protein and creatine is Momentous. Get 20% off your first purchase by using the code LIVINGPROOF at checkout at livemomentous.com IM8 With 92 nutrients, including Vitamin B12, Iodine, Selenium and Vitamin D, in highly absorbable forms, IM8 Daily Essentials is the perfect all-in-one daily multi-vitamin to ensure you meet your daily micronutrient needs. IM8 is offering an exclusive 10% off your first order with a free welcome kit when you enter the promo code SIMON at checkout on im8health.com Bragg Bragg Organic Apple Cider Vinegar is raw, unfiltered, and naturally fermented with 100% organic apples, always with the live “Mother” in every bottle. Get 20% off your first order at bragg.com with promo code SIMON. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Connect with Simon: Instagram: @simonhill X: @theproof Newsletter: theproof.com/newsletter Support the Show: If you found this helpful, please consider leaving a review on Apple Podcasts or Spotify, or sharing this episode with someone who’s on their own health journey. Subscribe and stay connected: Subscribe to The Proof on YouTube, Apple Podcasts or Spotify to ensure you never miss an episode. And don’t forget to follow me on Instagram and X for more insights and updates.

Transcribed - Published: 6 August 2025

In this episode, I’m joined by Dr. Rupy Aujla, NHS GP and founder of The Doctor’s Kitchen, to explore how food and lifestyle medicine can transform our health. We talk about his personal journey, why the medical system still overlooks nutrition, and how we can use simple, evidence-based principles to prevent disease and feel better. What we cover: Rupy’s story and why food became central to his practice The gap in nutrition training for doctors Lifestyle medicine and chronic disease Building a joyful, sustainable relationship with food Tips for people and practitioners feeling stuck For more, visit thedoctorskitchen.com and follow @doctors_kitchen on Instagram. Intro (00:00:00)Simplifying Nutrition Without Losing the Science (00:05:31)The Health Scare That Sparked a New Direction (00:12:57)How Nutrition Impacts Healing (00:20:19)Why Protein Matters More Than You Think (00:27:46)How Much Protein You Need & Why Some Say Less Is Better (00:33:44)Low Protein Signs (00:44:06)Why Plant Sources Gets Underrated (00:48:56)What Makes a Protein Source “High Quality” (00:57:28)Calorie Counting vs. Food Quality (01:03:28)How to Eat More Plant Protein Without Overthinking It (01:09:47)Should You Use Protein Powders? (01:21:28)Final Takeaway: BBGS and Protein Needs (01:28:33) Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family. This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. LMNT Stay hydrated with LMNT. Get a free Sample Pack of LMNT’s most popular drink mix flavors with any purchase at http://drinklmnt.com/SIMON. Find your favorite LMNT flavor, or share with a friend. And if you don’t like it? Full refund, no questions asked. Pique Tea Pique's Nandaka provides sustainable, all-day energy and makes you feel like you’re doing something good for your body! Try Pique and get 20% off plus a FREE starter kit when you shop exclusively at http://piquelife.com/simon. Eight Sleep Upgrade your sleep with the Pod 5 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF for $350 off at http://eightsleep.com/theproof. Try it risk-free for 30 days, with worldwide shipping. Function Health Take charge of your health with advanced blood testing and personalised insights. Function Health provides a practical solution to track key health markers such as cholesterol, blood sugar, and more. For the first 1,000 listeners, new members get a $100 credit when signing up. Head to functionhealth.com/simonhill to claim your credit. Only available to those living in the United States. Airbnb Right in the heart of the city, I’ve been hosting a hands-on Airbnb Experience at Little City Farm that’s all about plant diversity, gut health, and delicious food. For more information, or to find other experiences on your next trip, check out airbnb.com/experiences. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Simon Hill, MSc, BSc (Hons) Creator of theproof.com Host of The Proof with Simon Hill Author of The Proof is in the Plants Subscribe & Connect: YouTube Apple Podcasts Spotify Instagram: @simonhill Twitter: @theproof Facebook: The Proof with Simon Hill Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.

Transcribed - Published: 28 July 2025

This episode is the uncut conversation with Dr. Thomas Dayspring and Dr. Dan Soffer, unpacking the results of my coronary CT angiogram and CACS score. We explore what these scans reveal about cardiovascular risk, why good bloodwork isn’t always enough, and how to use tools like ApoB, Lp(a), and imaging to get a clearer picture of heart health. We also discuss statins, lifestyle changes, and the value of early prevention. Topics we cover: My coronary scan results explained What drives plaque and cardiovascular risk Advanced lipid testing (ApoB, Lp(a), LDL) Medication vs lifestyle: when and why Misconceptions about “normal” bloodwork What to do if your CAC score isn’t zero For anyone serious about long-term heart health, this is a must-listen. Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family. This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Bragg Bragg Organic Apple Cider Vinegar is raw, unfiltered, and naturally fermented with 100% organic apples, always with the live “Mother” in every bottle. Get 20% off your first order at bragg.com with promo code SIMON. IM8 With 92 nutrients, including Vitamin B12, Iodine, Selenium and Vitamin D, in highly absorbable forms, IM8 Daily Essentials is the perfect all-in-one daily multi-vitamin to ensure you meet your daily micronutrient needs. IM8 is offering an exclusive 10% off your first order with a free welcome kit when you enter the promo code SIMON at checkout on im8health.com Momentous My go-to supplement brand for protein and creatine is Momentous. Get 20% off your first purchase by using the code LIVINGPROOF at checkout at livemomentous.com Function Health Take charge of your health with advanced blood testing and personalised insights. Function Health provides a practical solution to track key health markers such as cholesterol, blood sugar, and more. For the first 1,000 listeners, new members get a $100 credit when signing up. Head to functionhealth.com/simonhill to claim your credit. Only available to those living in the United States. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Simon Hill, MSc, BSc (Hons) Creator of theproof.com Host of The Proof with Simon Hill Author of The Proof is in the Plants Subscribe & Connect: YouTube Apple Podcasts Spotify Instagram: @simonhill Twitter: @theproof Facebook: The Proof with Simon Hill Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.

Transcribed - Published: 21 July 2025

I just got back my latest blood test results, including over 100 biomarkers like hormone levels, nutrient status, cardiovascular risk, and my estimated biological age. In this solo episode, I walk you through the data and share what I’m doing to stay ahead of potential health issues before they snowball. In this episode: • Testosterone, estrogen & fertility markers • B12, omega-3s, vitamin D & a copper blind spot • Thyroid & metabolic health • LDL cholesterol and ApoB flagged for action • Environmental toxins & my biological age • Blood pressure: why it matters more than you think Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family. This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Function Health Take charge of your health with advanced blood testing and personalised insights. Function Health provides a practical solution to track key health markers such as cholesterol, blood sugar, and more. For the first 1,000 listeners, new members get a $100 credit when signing up. Head to functionhealth.com/simonhill to claim your credit. Only available to those living in the United States. IM8 With 92 nutrients, including Vitamin B12, Iodine, Selenium and Vitamin D, in highly absorbable forms, IM8 Daily Essentials is the perfect all-in-one daily multi-vitamin to ensure you meet your daily micronutrient needs. IM8 is offering an exclusive 10% off your first order with a free welcome kit when you enter the promo code SIMON at checkout on im8health.com Eight Sleep Upgrade your sleep with the Pod 5 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF for $350 off at eightsleep.com/theproof. Try it risk-free for 30 days, with worldwide shipping. Momentous My go-to supplement brand for protein and creatine is Momentous. Get 20% off your first purchase by using the code LIVINGPROOF at checkout at livemomentous.com Shopify Shopify, the world's leading e-commerce platform, helps you turn browsers into buyers with the internet’s best-converting check out–up to 36% better compared to other leading e-commerce platforms. To boost your conversion rate, and grow your business, sign up for a one-dollar-per-month trial period at shopify.com/proof. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Simon Hill, MSc, BSc (Hons) Creator of theproof.com Host of The Proof with Simon Hill Author of The Proof is in the Plants Subscribe & Connect: YouTube Apple Podcasts Spotify Instagram: @simonhill X: @theproof Facebook: The Proof with Simon Hill Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.

Transcribed - Published: 14 July 2025

I just got back my latest blood test results, including over 100 biomarkers like hormone levels, nutrient status, cardiovascular risk, and my estimated biological age. In this solo episode, I walk you through the data and share what I’m doing to stay ahead of potential health issues before they snowball. In this episode: Testosterone, estrogen, and fertility markers B12, omega-3s, vitamin D, and a copper blind spot Thyroid & metabolic health LDL cholesterol and ApoB flagged for action Environmental toxins and my biological age Blood pressure: why it matters more than you think Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family. This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Function Health Take charge of your health with advanced blood testing and personalised insights. Function Health provides a practical solution to track key health markers such as cholesterol, blood sugar, and more. For the first 1,000 listeners, new members get a $100 credit when signing up. Head to functionhealth.com/simonhill to claim your credit. Only available to those living in the United States. IM8 With 92 nutrients, including Vitamin B12, Iodine, Selenium and Vitamin D, in highly absorbable forms, IM8 Daily Essentials is the perfect all-in-one daily multi-vitamin to ensure you meet your daily micronutrient needs. IM8 is offering an exclusive 10% off your first order with a free welcome kit when you enter the promo code SIMON at checkout on im8health.com Eight Sleep Upgrade your sleep with the Pod 5 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF for $350 off at eightsleep.com/theproof. Try it risk-free for 30 days, with worldwide shipping. Momentous My go-to supplement brand for protein and creatine is Momentous. Get 20% off your first purchase by using the code LIVINGPROOF at checkout at livemomentous.com Shopify Shopify, the world's leading e-commerce platform, helps you turn browsers into buyers with the internet’s best-converting check out–up to 36% better compared to other leading e-commerce platforms. To boost your conversion rate, and grow your business, sign up for a one-dollar-per-month trial period at shopify.com/proof. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Simon Hill, MSc, BSc (Hons) Creator of theproof.com Host of The Proof with Simon Hill Author of The Proof is in the Plants Subscribe & Connect: YouTube Apple Podcasts Spotify Instagram: @simonhill X: @theproof Facebook: The Proof with Simon Hill Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.

Transcribed - Published: 14 July 2025

After 10 years of great blood work on a plant-based diet, I took things further with a coronary calcium scan and CT angiogram to see what’s really happening inside my arteries. The results? I have early signs of plaque. In this episode, I break down my numbers and speak with cardiologists Dr. Thomas Dayspring and Dr. Dan Soffer about what they mean for my long-term risk and yours. What we cover: My CT angiogram and CAC results How much plaque I have and where What ApoB and lifetime cholesterol exposure reveal How diet tweaks impacted my blood lipids Whether I should add medication What this means for others with “good” blood tests but family history Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family. This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Bragg Bragg Organic Apple Cider Vinegar is raw, unfiltered, and naturally fermented with 100% organic apples, always with the live “Mother” in every bottle. Get 20% off your first order at bragg.com with promo code SIMON. IM8 With 92 nutrients, including Vitamin B12, Iodine, Selenium and Vitamin D, in highly absorbable forms, IM8 Daily Essentials is the perfect all-in-one daily multi-vitamin to ensure you meet your daily micronutrient needs. IM8 is offering an exclusive 10% off your first order with a free welcome kit when you enter the promo code SIMON at checkout on im8health.com WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Simon Hill, MSc, BSc (Hons) Creator of theproof.com Host of The Proof with Simon Hill Author of The Proof is in the Plants Subscribe & Connect: YouTube Apple Podcasts Spotify Instagram: @simonhill X: @theproof Facebook: The Proof with Simon Hill Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.

Transcribed - Published: 8 July 2025

What does it really mean to eat well? In this episode, nutrition scientist Dr. Flávia Fayet-Moore joins me to explore the science of nutrient density, where most people fall short on key micronutrients, and why healthy eating doesn't have to mean giving up enjoyment or accessibility. We talk about the unintended effects of food messaging, the nuance of ultra-processed foods, and how better communication can actually improve population health. Topics covered: Intro (00:00:00) Why Nutrition Science Needs More Micronutrient Focus (00:05:00) Eating Habits & Deficiencies in Young Women (00:12:00) Milk, Juice & Rethinking Nutrient-Dense Drinks (00:30:00) Juice & Cardiometabolic Health: Surprising Findings (00:35:00) Cow’s Milk vs Plant Milks: Nutrients, Fortification & Formulation (00:56:00) Vitamin D, Sunlight & The Power of Mushrooms (01:09:00) Folate, Iron & The Risks of Over-Supplementation (01:30:00) Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family. This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. IM8 With 92 nutrients, including Vitamin B12, Iodine, Selenium and Vitamin D, in highly absorbable forms, IM8 Daily Essentials is the perfect all-in-one daily multi-vitamin to ensure you meet your daily micronutrient needs. IM8 is offering an exclusive 10% off your first order with a free welcome kit when you enter the promo code SIMON at checkout on im8health.com Function Health Take charge of your health with advanced blood testing and personalised insights. Function Health provides a practical solution to track key health markers such as cholesterol, blood sugar, and more. For the first 1,000 listeners, new members get a $100 credit when signing up. Head to functionhealth.com/simonhill to claim your credit. Only available to those living in the United States. Pique Tea Pique's Nandaka provides sustainable, all-day energy and makes you feel like you’re doing something good for your body! Try Pique and get 20% off plus a FREE starter kit when you shop exclusively at Piquelife.com/simon. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Simon Hill, MSc, BSc (Hons) Creator of theproof.com Host of The Proof with Simon Hill Author of The Proof is in the Plants Subscribe & Connect: YouTube Apple Podcasts Spotify Instagram: @simonhill X: @theproof Facebook: The Proof with Simon Hill Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.

Transcribed - Published: 30 June 2025

In this solo episode, I unpack the controversial new KETO-CTA study and why its conclusions about cholesterol, ApoB, and ketogenic diets aren’t as clear as they seem. We break down what the study really found, how it was communicated, and what it means if you (or someone you care about) is following a high-fat, low-carb diet with elevated LDL-C. With expert commentary from Dr. Alan Flanagan, we explore: Who Lean Mass Hyper-Responders (LMHRs) are Why the study isn’t actually a “trial” The missing data on plaque progression and what was left out What non-calcified plaque volume (NCPV) tells us Whether this study really challenges ApoB’s role in heart disease Why communication matters and how headlines can mislead What this means for keto diets, cardiovascular risk, and informed decisions If you found this valuable, please share it or leave a review. Every share helps the truth cut through the noise. Intro: Can You Be “Healthy” with Sky-High LDL on Keto? (00:00) What the Keto CTA Study Was Trying to Prove (01:36) The Problem: This Wasn’t Actually a Clinical Trial (03:57) APOB Focused, But Not Pre-Registered: Red Flag #1 (07:58) Real Plaque Progression Numbers: 4x Faster Than Healthy Controls (09:16) So… Does ApoB Matter or Not? (17:50) How the Study Was Communicated to the Public (26:03) What the Headlines Should Actually Say (37:05) Final Thoughts from Dr. Carvallo and Dr. Flanagan (38:06) Key Takeaways (40:37) Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family. This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code PROOF for 25% off at checkout. Bragg Bragg Organic Apple Cider Vinegar is raw, unfiltered, and naturally fermented with 100% organic apples, always with the live “Mother” in every bottle. Get 20% off your first order at bragg.com with promo code SIMON. IM8 With 92 nutrients, including Vitamin B12, Iodine, Selenium and Vitamin D, in highly absorbable forms, IM8 Daily Essentials is the perfect all-in-one daily multi-vitamin to ensure you meet your daily micronutrient needs. IM8 is offering an exclusive 10% off your first order with a free welcome kit when you enter the promo code SIMON at checkout on im8health.com LMNT Stay hydrated with LMNT. Get a free Sample Pack of LMNT’s most popular drink mix flavours with any purchase at DrinkLMNT.com/SIMON Find your favourite LMNT flavour, or share with a friend. And if you don’t like it? Full refund, no questions asked. Eight Sleep Upgrade your sleep with the Pod 5 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF for $350 off at eightsleep.com/theproof. Try it risk-free for 30 days, with worldwide shipping. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Simon Hill, MSc, BSc (Hons) Creator of theproof.com Host of The Proof with Simon Hill Author of The Proof is in the Plants Subscribe & Connect: YouTube Apple Podcasts Spotify Instagram: @simonhill X: @theproof Facebook: The Proof with Simon Hill Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.

Transcribed - Published: 24 June 2025

In this rapid-fire solo episode, I’m answering your questions straight from the community. From creatine and multivitamins to cardiovascular risk, sea moss, weight gain, soy, grief, and more, no fluff, just focused insights backed by science. What I cover: What matters more when choosing creatine: NSF certification or Creapure Should you take creatine daily? Healthy weight gain strategies Key cardiovascular blood markers to track How to manage high Lp(a) and familial hypercholesterolemia Thoughts on sea moss, multivitamins, soy, oils, and ultra-processed foods How much protein is enough on a plant-based diet Personal updates on running, sleep, and a new iron absorption study Reflections on grief, gratitude, and future plans Want to dive deeper into any of these topics? Explore links to studies, products, and past episodes at theproof.com. Intro (00:00) Creatine: Best Type & Daily Use Explained (00:00:46) How to Gain Healthy Weight on a Plant-Based Diet (00:02:15) Essential Blood Tests for Heart Health (00:03:55) CGMs for Non-Diabetics: Helpful or Hype? (00:06:02) Saunas & Longevity: What the Science Says (00:07:02) Lp(a), ApoB & Cholesterol: What Actually Matters? (00:08:36) Can You Reduce Familial Hypercholesterolemia Risk? (00:13:05) How Low Should LDL Go? (00:16:04) Iron Absorption in Vegans vs Omnivores (00:16:41) Best Sources of Protein on a Plant-Based Diet (00:20:22) Key Nutrient Tests for Vegans (00:21:46) Multivitamins & Pescatarian Diets: Are They Worth It? (00:22:26) Supplements for Bone Health: Vitamin K2, D & More (00:27:31) Sea Moss & CoQ10: Superfoods or Marketing? (00:28:41) Is Soy Really Bad for You? (00:30:14) Are Oils Healthy? What to Know About Fats (00:31:41) Zone 2 Training: How Much Do You Need? (00:37:06) Do You Eat Ultra-Processed Vegan Food? (00:40:37) Why This Work Matters & What Drives the Mission (00:44:55) Outro (00:49:45) Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family. This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for 10% off at checkout. Function Health Take charge of your health with advanced blood testing and personalised insights. Function Health provides a practical solution to track key health markers such as cholesterol, blood sugar, and more. For the first 1,000 listeners, new members get a $100 credit when signing up. Head to functionhealth.com/simonhill to claim your credit. Only available to those living in the United States. Momentous My go-to supplement brand for protein and creatine is Momentous. Get 20% off your first purchase by using the code LIVINGPROOF at checkout at livemomentous.com Pique Tea Pique's Nandaka provides sustainable, all-day energy and makes you feel like you’re doing something good for your body! Try Pique and get 20% off plus a FREE starter kit when you shop exclusively at Piquelife.com/simon. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Simon Hill, MSc, BSc (Hons) Creator of theproof.com Host of The Proof with Simon Hill Author of The Proof is in the Plants Subscribe & Connect: YouTube Apple Podcasts Spotify Instagram: @simonhill X: @theproof Facebook: The Proof with Simon Hill Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.

Transcribed - Published: 16 June 2025

What if trying to feel good all the time is actually keeping you stuck? In this episode of The Proof, I’m joined by Dr. Emily Musgrove, clinical psychologist and author of Unstuck, to explore why emotional discomfort isn’t something to avoid, but something to understand. We unpack what it really means to be “stuck,” how avoidance sneaks into everyday life (even among high performers), and the role of values, awareness, and psychological flexibility in creating meaningful change. In this episode, we cover: Why feeling stuck doesn’t mean you’re broken How emotional avoidance drives disconnection The difference between psychological flexibility and cognitive fusion The cost of always performing and staying polished Hedonic vs. eudaimonic wellbeing How to clarify values and live with intention One practical step to start moving forward If you’re feeling overwhelmed, burned out, or just unsure of what’s next, this conversation offers clarity, compassion, and tools to help you reconnect with what matters. Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family. This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code PROOF for 25% off at checkout. Fireflies Stay focused and let Fireflies handle the notes. From transcriptions and summaries to real-time voice commands, Fireflies turns your meetings into actionable insights, seamlessly integrating with Zoom, Google Meet, Slack, and more. Sign up for a yearly plan and get two months FREE at fireflies.ai/theproof. Bragg Bragg Organic Apple Cider Vinegar is raw, unfiltered, and naturally fermented with 100% organic apples, always with the live “Mother” in every bottle. Get 20% off your first order at bragg.com with promo code SIMON. Shopify Shopify, the world's leading e-commerce platform, helps you turn browsers into buyers with the internet’s best-converting check out–up to 36% better compared to other leading e-commerce platforms. To boost your conversion rate, and grow your business, sign up for a one-dollar-per-month trial period at shopify.com/proof. Eight Sleep Upgrade your sleep with the Pod 5 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF for $350 off at eightsleep.com/theproof. Try it risk-free for 30 days, with worldwide shipping. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Simon Hill, MSc, BSc (Hons) Creator of theproof.com Host of The Proof with Simon Hill Author of The Proof is in the Plants Subscribe & Connect: YouTube Apple Podcasts Spotify Instagram: @simonhill Twitter: @theproof Facebook: The Proof with Simon Hill Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.

Transcribed - Published: 9 June 2025

This week, I’m sharing a conversation I had as a guest on Food For Thought, the podcast hosted by registered nutritionist Rhiannon Lambert. We covered everything from protein and plant-based diets to the role of ultra-processed foods in chronic disease, and how to better interpret nutrition science in a world full of misinformation. In this episode, I cover: How to think critically about nutrition research The impact of plant-based diets on human and planetary health Protein quality and building muscle with plants The role of ultra-processed foods in long-term health Social media’s influence on nutrition discourse What phytates are and whether they matter This is a repost of my chat with Rhiannon. You can find her podcast and more of her work at rhitrition.com/podcast. Intro: The Science Behind Plant-Based Nutrition and Longevity (00:00) Simon's Journey from Sports Physio to Nutrition Science Advocate (00:35) Why Nutrition Science Requires Context and Nuance (05:12) Debunking Common Nutrition Myths with Evidence (05:59) Health Benefits of Adopting a Plant-Based Diet (15:30) Protein and Muscle: Separating Myths from Data (21:42) Key Nutrients to Monitor in Plant-Based Eating (31:21) Understanding Calories: Not All Energy Is Equal (35:56) Phytates and Mineral Absorption: Myths vs. Mechanisms (43:55) Environmental Impact of Dietary Choices: Data-Driven Insights (50:22) Fact or Fiction: Science-Based Answers to Nutrition Claims (55:02) Final Thoughts: Navigating Nutrition Science with Integrity (01:00:55) Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family. This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code PROOF for 25% off at checkout. Function Health Take charge of your health with advanced blood testing and personalised insights. Function Health provides a practical solution to track key health markers such as cholesterol, blood sugar, and more. For the first 1,000 listeners, new members get a $100 credit when signing up. Head to functionhealth.com/simonhill to claim your credit. Only available to those living in the United States. Momentous My go-to supplement brand for protein and creatine is Momentous. Get 20% off your first purchase by using the code LIVINGPROOF at checkout at livemomentous.com Eight Sleep Upgrade your sleep with the Pod 5 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF for $350 off at eightsleep.com/theproof. Try it risk-free for 30 days, with worldwide shipping. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Follow this link for 20% off one-time purchases and subscriptions. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Simon Hill, MSc, BSc (Hons) Creator of theproof.com Host of The Proof with Simon Hill Author of The Proof is in the Plants Subscribe & Connect: YouTube Apple Podcasts Spotify Instagram: @simonhill Twitter: @theproof Facebook: The Proof with Simon Hill Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.

Transcribed - Published: 2 June 2025

Heart disease doesn’t start when you’re older, it starts early, often without symptoms. In this episode, I speak with Dr. Laurence Sperling, one of the world’s leading experts in preventive cardiology, to explore how to catch heart disease early and stop it in its tracks. We cover cholesterol, blood pressure, calcium scores, lifestyle, and more. This is one of the most practical, empowering episodes on heart health I’ve ever recorded. What we cover: Early detection and the true origins of atherosclerosis How low your cholesterol and blood pressure should really be Understanding ApoB, Lp(a), and genetic risk When it’s worth getting a CT scan Lifestyle and medical interventions that actually work Whether you’re 25 or 65, this conversation is packed with insights that can help you live longer and better by understanding and protecting your cardiovascular system. 0:00:00 – Intro 0:01:24 - Why Prevention Should Start Before Birth 0:10:11 – Is It Genetics or Lifestyle? Understanding Risk 0:16:17 – Public Health Strategy That Prevents Millions of Heart Attacks 0:21:55 - How Geography and Income Impact Heart Disease Risk 0:29:25 – Familial Hypercholesterolemia and Lifetime Cholesterol Exposure 0:34:00 – What Diet and Lifestyle Patterns Lower Risk Long-Term 0:45:49 – LDL, HDL, and the New Science of Non-HDL Cholesterol 0:53:39 - Does High Blood Pressure Still Harm Arteries if ApoB Is Low? 1:05:24 – Lipoprotein(a): The Triple Threat You Should Know About 1:08:22 – When Should You Start Cardiac Risk Assessments? 1:17:23 - Can a Calcium Score of Zero Be Misleading in Younger Adults? 1:23:58 – CT Calcium vs. CT Angiogram: Which Scan Is Right? 1:33:25 - Is Subclinical Atherosclerosis the Same as Heart Disease? 1:40:03 - What Are Optimal LDL and Blood Pressure Levels to Prevent Heart Disease? 1:48:07 – How GLP-1 Drugs Help With Weight and Heart Disease Prevention 1:57:10 – Public Health Policies That Could Save Millions 2:01:19 – Cardiologist-Approved Daily Habits for a Healthy Heart 2:05:20 – Outro This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code PROOF for 25% off at checkout. LMNT Stay hydrated with LMNT. Try their limited-time Lemonade Salt flavour - salty, tart, and super refreshing. Receive a free LMNT sample pack with any order when you purchase via drinklmnt.com/simon. And if you don’t like it? Full refund — no questions asked. Pique Tea Pique's Nandaka provides sustainable, all-day energy and makes you feel like you’re doing something good for your body! Try Pique and get 20% off plus a FREE starter kit when you shop exclusively at Piquelife.com/simon. Eight Sleep Upgrade your sleep with the Pod 5 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF for $350 off at eightsleep.com/theproof. Try it risk-free for 30 days, with worldwide shipping. Function Health Take charge of your health with advanced blood testing and personalised insights. Function Health provides a practical solution to track key health markers such as cholesterol, blood sugar, and more. For the first 1,000 listeners, new members get a $100 credit when signing up. Head to functionhealth.com/simonhill to claim your credit. Only available to those living in the United States. Simon Hill, MSc, BSc (Hons) Creator of theproof.com Host of The Proof with Simon Hill Author of The Proof is in the Plants Subscribe & Connect: YouTube Apple Podcasts Spotify Instagram: @simonhill Twitter: @theproof Facebook: The Proof with Simon Hill Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.

Transcribed - Published: 26 May 2025

Dr. Sharon Bergquist joins me to explore a powerful reframe: stress isn’t always bad. In fact, certain types of stress, when dosed right, are essential for building resilience and longevity. We talk about “eustress,” hormesis, and how everyday tools like exercise, fasting, and even hot or cold exposure can activate the body’s repair systems at the cellular level. Sharon explains why recovery is just as critical as the stressor itself, and how aligning your lifestyle with your values may be one of the most impactful health moves of all. Overview of the Stress Paradox (00:00) Good Stress vs. Bad Stress: What’s the Difference? (01:55) Understanding Stress: Eustress, Distress & Sustress (04:04) How Stress Changes Your Body’s Baseline Permanently? (09:20) Why Discomfort Is Required for Long-Term Health (11:38) What Is Hormesis and How It Regenerates Your Body (17:00) 7 Repair Systems Activated by Good Stress (17:42) Recovery Matters: The Missing Piece in Stress Resilience (23:44) The Blood Markers That Show If Your Stress Routine Is Working (29:23) The Best Type of Stress for Improving Metabolic Health (33:59) Do Good Stressors Slow Aging (35:18) What Is Psychological Stress and Can It Be Good for You? (41:00) The 5 Good Stressors That Boost Resilience and Longevity (45:55) The Science Behind Phytochemicals and Stress Adaptation (46:22) What Are Phytochemicals? Nature’s Defence Compounds (54:55) Intermittent Fasting Explained: Finding Your Goldilocks Zone (01:00:42) Combining Fasting with Exercise: Best Practices for Balance (01:10:38) High-Intensity Training and Mitochondrial Health Benefits (01:15:18) Heat and Cold Therapy: Saunas, Ice Baths and Hormetic Effects (01:28:02) Psychological Stress and Cellular Health: The Mind-Body Link (01:36:32) Final Takeaways: Building a Resilient, Healthier You (01:43:24) If you’ve ever felt overwhelmed by stress or tried to avoid it entirely, this conversation offers a new, empowering perspective. Share this episode with someone who’d benefit from rethinking their relationship with stress. This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Function Health Take charge of your health with advanced blood testing and personalised insights. Function Health provides a practical solution to track key health markers such as cholesterol, blood sugar, and more. For the first 1,000 listeners, new members get a $100 credit when signing up. Head to functionhealth.com/simonhill to claim your credit. Only available to those living in the United States. Momentous My go-to supplement brand for protein and creatine is Momentous. Get 20% off your first purchase by using the code LIVINGPROOF at checkout at livemomentous.com Eight Sleep Upgrade your sleep with the Pod 5 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF for $350 off at eightsleep.com/theproof. Try it risk-free for 30 days, with worldwide shipping. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Follow this link  for 20% off one-time purchases and subscriptions. Simon Hill, MSc, BSc (Hons) • Creator of theproof.com • Host of The Proof with Simon Hill • Author of The Proof is in the Plants Subscribe & Connect: • YouTube • Apple Podcasts • Spotify • Instagram: @simonhill • Twitter: @theproof • Facebook: The Proof with Simon Hill Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.

Transcribed - Published: 19 May 2025

In this episode of The Proof, I’m joined by Dr. Steven Novella, a clinical neurologist at Yale School of Medicine and host of The Skeptics’ Guide to the Universe. Steven has spent decades helping people think more clearly, spot misinformation, and navigate the increasingly noisy world of science, health, and media. Together we explore what it really means to be a skeptic — not a cynic — and why scientific humility is more powerful than absolute certainty. We talk about how to have better conversations with people who believe in conspiracy theories, the psychology behind motivated reasoning, and why embracing “I don’t know” can actually make us more grounded, not less. What we cover: Scepticism vs. denialism Why stories often override facts What science literacy actually looks like The cognitive traps we all fall into How social media fuels misinformation Rebuilding trust in science and institutions If you enjoy this episode, I’d love it if you shared it with someone who values critical thinking and curiosity. 00:00 Introduction 05:48 Sceptic vs. Contrarian: What's the difference? 08:57 Combating Misinformation and Disinformation 12:13 The Role of Critical Thinking 18:06 Why We Reject Facts That Make Us Uncomfortable 21:09 How Echo Chambers Hijack Reality 24:41 The Hardest Choice: Truth or Belonging? 37:54 Why People No Longer Trust Experts 48:16 Debating Pseudoscience 52:53 The Deadly Cost of Misinformation 56:03 The GMO Lies People Still Believe 01:03:00 How to Teach Critical Thinking to Anyone 01:10:00 How to Think, Not What to Think 01:14:34 Why Science Sounds Uncertain and Why That’s a Good Thing 01:23:51 Being Sceptical Doesn’t Make You Automatically Right 01:35:59 The Double-Edged Sword of AI This episode is brought to you by: 38TERA Consider 38TERA's ⁠DMN prebiotic supplement⁠ a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Function Health Take charge of your health with advanced blood testing and personalised insights. Function Health provides a practical solution to track key health markers such as cholesterol, blood sugar, and more. For the first 1,000 listeners, new members get a $100 credit when signing up. Head to ⁠functionhealth.com/simonhill⁠ to claim your credit. Only available to those living in the United States. Momentous My go-to supplement brand for protein and creatine is Momentous. Get 20% off your first purchase by using the code LIVINGPROOF at checkout at ⁠livemomentous.com⁠ Shopify Shopify, the world's leading e-commerce platform, helps you turn browsers into buyers with the internet’s best-converting check out–up to 36% better compared to other leading e-commerce platforms. To boost your conversion rate, and grow your business, sign up for a one-dollar-per-month trial period at ⁠shopify.com/proof⁠. Birch Sleep deeply and wake up refreshed with a Birch Natural Mattress, combining premium natural materials with unbeatable comfort. Rest easy with a 100-night trial and 25-year warranty. Get 20% off sitewide and 2 free Eco-Rest Pillows at ⁠birchliving.com/simonhill⁠. Pique Tea Pique's Nandaka provides sustainable, all-day energy and makes you feel like you’re doing something good for your body! Try Pique and get 20% off plus a FREE starter kit when you shop exclusively at ⁠Piquelife.com/simon⁠. Simon Hill, MSc, BSc (Hons) • Creator of ⁠theproof.com⁠ • Host of ⁠The Proof with Simon Hill⁠ • Author of ⁠The Proof is in the Plants⁠ Subscribe & Connect: • ⁠YouTube⁠ • ⁠Apple Podcasts⁠ • ⁠Spotify⁠ • Instagram: ⁠@simonhill⁠ • Twitter: ⁠@theproof⁠ • Facebook: ⁠The Proof with Simon Hill⁠ Nourish your gut with my ⁠Plant-Based Ferments Guide⁠ and download my ⁠Two-Week Meal Plan⁠.

Transcribed - Published: 12 May 2025

In this AMA episode of The Proof, I take your questions on everything from reversing plaque buildup to fasted cardio, the safety of seed oils, and how to bounce back after antibiotics. These episodes are a chance to share where my thinking is currently at grounded in science, but always evolving. In this episode, I cover: Most underrated foods for long-term health Can we reverse plaque in arteries or just slow it down? Seed oils: worth avoiding or overblown fear? Gut health recovery post-antibiotics Fasted cardio for fat loss: what the data says Supplements I take daily (and ones I skip) Carnivore diet, meat and the planet: separating science from spin Key habits for pregnancy, longevity, and daily performance A few thoughts on alcohol, morning routines & personal growth Whether you’re looking to refine your health habits or just curious about the latest science on hot topics, I hope this one helps bring a little clarity and inspiration. Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family. This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Eight Sleep Upgrade your sleep with the Pod 4 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF for $350 off at eightsleep.com/theproof. Try it risk-free for 30 days, with worldwide shipping. Function Health Take charge of your health with advanced blood testing and personalised insights. Function Health provides a practical solution to track key health markers such as cholesterol, blood sugar, and more. For the first 1,000 listeners, new members get a $100 credit when signing up. Head to functionhealth.com/simonhill to claim your credit. Only available to those living in the United States. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Follow https://eimele.com/essential-8/15660280.html. for 20% off one-time purchases and subscriptions. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Simon Hill, MSc, BSc (Hons) • Creator of theproof.com • Host of The Proof with Simon Hill • Author of The Proof is in the Plants Subscribe & Connect: • YouTube • Apple Podcasts • Spotify • Instagram: @simonhill • Twitter: @theproof • Facebook: The Proof with Simon Hill Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.

Transcribed - Published: 7 May 2025

In this solo episode of The Proof, I explore how to turn your gut into a thriving ecosystem and what might be silently harming it. You’ll learn the top 3 things to do for your microbiome, the 3 biggest mistakes to avoid, and how to support gut recovery after antibiotics. Specifically, I cover: How your microbiome affects immunity, mood, metabolism, and more The best foods and habits to feed your gut My antibiotic recovery protocol Why plant diversity matters more than your diet label Gut health myths (like probiotic hype and “7-day resets”) Signs your gut health is improving without testing Science-backed and practical. No fads, just evidence. How to Transform Your Gut Health Naturally (00:00) What Is the Gut Microbiome? (01:27) How Your Microbiome Supports the Immune System (02:08) The Gut-Brain Connection: How Microbes Influence Mood (03:17) Why the Gut Microbiome Changes Daily — And What It Means for Your Health (04:18) Top Expert-Backed Tips for a Healthy Gut Microbiome (04:43) Why Plant Diversity Is Crucial for Gut Health (05:15) Best Fermented Foods to Improve Gut Health (11:42) How Lifestyle Affects Your Gut Microbiome (15:35) Busting the Biggest Gut Health Myths (18:00) What’s Harming Your Gut? 3 Practices to Avoid (18:54) How to Heal Your Gut After Taking Antibiotics (20:47) Key Takeaways for Long-Term Gut Health Success (28:43) Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family. This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Pique Tea Pique's Nandaka provides sustainable, all-day energy and makes you feel like you’re doing something good for your body! Try Pique and get 20% off plus a FREE starter kit when you shop exclusively at Piquelife.com/simon. Function Health Track, optimise, and thrive with Function Health. Access 100+ lab tests – five times more than a typical physical – including ApoB and LP(a), no doctor approval needed. Get science-backed insights and track your results over time. Skip the 400,000-person waitlist at functionhealth.com/simonhill. Only available to those living in the United States. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Follow [this link](https://eimele.com/essential-8/15660280.html.) for 20% off one-time purchases and subscriptions. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Simon Hill, MSc, BSc (Hons) • Creator of theproof.com • Host of The Proof with Simon Hill • Author of The Proof is in the Plants Subscribe & Connect: • YouTube • Apple Podcasts • Spotify • Instagram: @simonhill • Twitter: @theproof • Facebook: The Proof with Simon Hill Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.

Transcribed - Published: 30 April 2025

How can we protect our brain as we age and what can we do today to boost memory, focus, and resilience? In this episode of The Proof, I’ve compiled some of the most impactful conversations I’ve had with leading neuroscientists, neurologists, and brain health researchers to explore exactly that. From building better habits to slowing age-related decline, this masterclass brings you practical, science-backed strategies for optimising brain function, now and in the future. Whether your goal is sharper mental clarity, prevention of neurodegenerative disease, or simply staying sharp for the long haul, this episode is packed with insights you can use right away. You’ll learn: • How neuroplasticity allows your brain to adapt and change at any age • The role of movement and VO₂ max in protecting cognitive performance • How omega-3s and dietary fats impact brain structure and function • What APOE4 means for your risk of Alzheimer’s and why genetics aren’t destiny • The link between cardiovascular health, lipoproteins, and dementia • How the microbiome and inflammation influence brain aging • The surprising ways exercise improves brain volume and connectivity • Why creatine isn’t just for muscles and how it may enhance mental energy and mood • Actionable daily habits to reduce your risk of cognitive decline • The truth about lifestyle vs genetics when it comes to Alzheimer’s disease Featuring insights from Dr Andrew Huberman, Dr Ayesha Sherzai, Dr Dean Sherzai, Dr Thomas Dayspring, and Dr Kellyann Niotis, this episode distills cutting-edge neuroscience into clear, practical guidance for long-term cognitive health. Thank you for tuning in to today’s episode, and special thanks to the experts featured for their invaluable insights. If you found this episode helpful, please share it with someone who you think might benefit from it. Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family. This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Function Health Track, optimise, and thrive with Function Health. Access 100+ lab tests – five times more than a typical physical – including ApoB and LP(a), no doctor approval needed. Get science-backed insights and track your results over time. Skip the 400,000-person waitlist at functionhealth.com/simonhill. Only available to those living in the United States. Eight Sleep Upgrade your sleep with the Pod 4 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF for $350 off at eightsleep.com/theproof. Try it risk-free for 30 days, with worldwide shipping. Momentous My go-to supplement brand for protein and creatine is Momentous. Get 20% off your first purchase by using the code LIVINGPROOF at checkout at livemomentous.com Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Follow [this link](https://eimele.com/essential-8/15660280.html.) for 20% off one-time purchases and subscriptions. Simon Hill, MSc, BSc (Hons) • Creator of theproof.com • Host of The Proof with Simon Hill • Author of The Proof is in the Plants Subscribe & Connect: • YouTube • Apple Podcasts • Spotify • Instagram: @simonhill • Twitter: @theproof • Facebook: The Proof with Simon Hill Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.

Transcribed - Published: 21 April 2025

In today’s episode Dr Matthew Nagra returns to The Proof to break down a new JAMA Internal Medicine study on butter, plant-based oils, and mortality. Over 200,000 Americans were followed for 33 years — so what did the research really find? We unpack the study’s most talked-about claims, including whether swapping just 10g of butter for plant-based oil could lower your risk of early death. Plus, we dive into the bigger picture: Why fats are so polarising, the debate around seed oils, and how to navigate nutrition science in an era of misinformation. Specifically, we cover: Inside a Controversial New Study on Butter and Plant Oils (00:00) How the 33-Year Nutrition Study Was Conducted (00:47) What Observational Studies Can (and Can’t) Tell Us (03:01) The Truth About Food Frequency Questionnaires (08:03) Surprising Patterns in Butter and Oil Consumption (17:52) Why One Common Oil Performed Better Than Expected (22:50) Are We Misunderstanding Nutrition Guidelines? (26:13) What Happens When Oils Are Heated Over and Over (28:28) Do Oils Measure Up to Whole Food Fat Sources? (31:04) The Great Oil Debate: A Preview and Reflection (34:07) A Smarter Way to Navigate Conflicting Health Advice (43:40) Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family. This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Momentous My go-to supplement brand for protein and creatine is Momentous. Get 20% off your first purchase by using the code LIVINGPROOF at checkout at livemomentous.com Shopify Shopify, the world's leading e-commerce platform, helps you turn browsers into buyers with the internet’s best-converting check out–up to 36% better compared to other leading e-commerce platforms. To boost your conversion rate, and grow your business, sign up for a one-dollar-per-month trial period at shopify.com/proof. Birch Sleep deeply and wake up refreshed with a Birch Natural Mattress, combining premium natural materials with unbeatable comfort. Rest easy with a 100-night trial and 25-year warranty. Get 20% off sitewide and 2 free Eco-Rest Pillows at birchliving.com/simonhill. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Follow [this link](https://eimele.com/essential-8/15660280.html.) for 20% off one-time purchases and subscriptions. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Simon Hill, MSc, BSc (Hons) • Creator of theproof.com • Host of The Proof with Simon Hill • Author of The Proof is in the Plants Subscribe & Connect: • YouTube • Apple Podcasts • Spotify • Instagram: @simonhill • Twitter: @theproof • Facebook: The Proof with Simon Hill Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.

Transcribed - Published: 14 April 2025

What if losing body fat didn’t have to be so difficult? In this episode, I share five practical, science-backed strategies to support fat loss in a sustainable way. No gimmicks. No pseudo-science. Just real tools to help you feel fuller, fuel your body better, and improve metabolic health. Whether your goal is to reduce visceral fat or feel more confident in your body, these strategies can help — and you don’t need to do them all at once to see results. In this episode, I cover: Why energy density matters The “preload” trick that helps regulate intake How eating slower naturally reduces appetite The surprising role of gut microbes in hunger Why protein + fibre is the ultimate combo A flexible approach to time-restricted eating Plus, I bust common weight loss myths and share why improving body composition is about more than aesthetics. If you’re ready for a science-based, sustainable approach to fat loss — without restriction — this episode is for you. Introduction (00:00) Should You Choose Low Energy Dense Foods? (01:39) Could Slowing Down Your Eating Help? (07:51) How Can You Feed Your Gut Microbes? (12:29) Why Increase Your Protein Intake? (15:41) Does Reducing Your Eating Window Work? (19:27) Recap and Final Thoughts (21:03) Conclusions (22:16) Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family. This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for 25% at checkout. Eight Sleep Upgrade your sleep with the Pod 4 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF for $350 off at eightsleep.com/theproof. Try it risk-free for 30 days, with worldwide shipping. Function Health Track, optimise, and thrive with Function Health. Access 100+ lab tests – five times more than a typical physical – including ApoB and LP(a), no doctor approval needed. Get science-backed insights and track your results over time. Skip the 400,000-person waitlist at functionhealth.com/simonhill. Only available to those living in the United States. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Follow [this link](https://eimele.com/essential-8/15660280.html.) for 20% off one-time purchases and subscriptions. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Simon Hill, MSc, BSc (Hons) • Creator of theproof.com • Host of The Proof with Simon Hill • Author of The Proof is in the Plants Subscribe & Connect: • YouTube • Apple Podcasts • Spotify • Instagram: @simonhill • Twitter: @theproof • Facebook: The Proof with Simon Hill Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.

Transcribed - Published: 8 April 2025

Welcome to the very first episode of a brand new format - something a little more relaxed, more personal, and more conversational. Think of this as us sitting on the couch or going for a long walk together. No script. No structure. Just your questions, and my honest thoughts. In this episode, I answer your voice notes and DMs - covering: Intro (00:00) How Can New Fathers Balance Fitness and Diet with a Busy Life? (02:20) What Are the Risks and Benefits of Methylene Blue? (12:20) What Are the Biggest Nutrition Myths Still Believed in 2025? (16:59) Why Do Some Plant-Based Eaters Still Have High Cholesterol? (19:52) What Are the Best Alternatives to Statins for Lowering APOB? (23:32) What Health Habits Does Simon Hill Personally Struggle With? (32:41) Are Refined Carbohydrates Like Pasta and White Rice Actually Bad for You? (34:09) What’s the Future of Personalised Nutrition? (40:16) What’s the Most Embarrassing Travel Story Simon Has Shared? (44:33) What Does “Bogan” Mean in Australian Slang? (47:49) How Much Omega-3 Do You Really Need Daily? (50:06) Does Creatine Supplementation Harm Your Kidneys? (56:10) What’s the Perfect Meal for Human and Planetary Health? (01:00:31) Can the Power of Belief Affect Your Health Outcomes? (01:03:05) What’s the Funniest Listener Question and Final Thoughts? (01:04:11) Some serious, some silly - but all of it real. I hope you enjoy this new format, and as always, I’d love your feedback. Let me know what you liked, didn’t like, and what you’d love to see more of in future episodes. If you’d like to leave a question for a future Q&A episode, you can do that in the YT comments or send a message on IG instagram.com/simonhill. Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family. This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Birch Sleep deeply and wake up refreshed with a Birch Natural Mattress, combining premium natural materials with unbeatable comfort. Rest easy with a 100-night trial and 25-year warranty. Get 20% off sitewide and 2 free Eco-Rest Pillows at birchliving.com/simonhill. Pique Tea Pique's Nandaka provides sustainable, all-day energy and makes you feel like you’re doing something good for your body! Try Pique and get 20% off plus a FREE starter kit when you shop exclusively at Piquelife.com/simon. Eight Sleep Upgrade your sleep with the Pod 4 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF for $350 off at eightsleep.com/theproof. Try it risk-free for 30 days, with worldwide shipping. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Follow [this link](https://eimele.com/essential-8/15660280.html.) for 20% off one-time purchases and subscriptions. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Simon Hill, MSc, BSc (Hons) • Creator of theproof.com • Host of The Proof with Simon Hill • Author of The Proof is in the Plants Subscribe & Connect: • YouTube • Apple Podcasts • Spotify • Instagram: @simonhill • Twitter: @theproof • Facebook: The Proof with Simon Hill Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.

Transcribed - Published: 31 March 2025

Are seed oils actually harmful? Or is this just another wellness myth gone viral? In this episode, I sit down with Dr. Bill Harris - leading expert on dietary fats - to unpack the science on linoleic acid, an omega-6 fat found in nuts, seeds, and vegetable oils. We explore the rise of seed oil fear-mongering, the truth about inflammation, cholesterol, oxidation, and why outcome data—not mechanisms—should guide our thinking. Omega-6 Fats and Health Overview (00:00) Why the Review Was Updated (01:22) What Is Linoleic Acid? (06:47) Linoleic Intake Over Time & Health Links (12:45) Research Methods and Key Evidence (16:25) Omega-6 and Inflammation Explained (41:00) Common Myths About Seed Oils (44:37) The Oxidation Concern with Seed Oils (49:20) Omega-6 vs Omega-3: The Real Story (53:39) Blood Sugar, Insulin & Linoleic Acid (01:03:48) Heart Health and Linoleic Benefits (01:05:44) Cancer Risk and Seed Oils (01:13:49) Public Health and Future Research (01:16:55) How to Use Vegetable Oils Wisely (01:25:17) Wrap-Up and Takeaway Advice (01:32:22) If you’ve been confused by the seed oil debate, this one’s for you. Visit The Proof website for the full show notes and supporting studies. Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family. This episode is brought to you by: 38TERA Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Function Health Track, optimise, and thrive with Function Health. Access 100+ lab tests – five times more than a typical physical – including ApoB and LP(a), no doctor approval needed. Get science-backed insights and track your results over time. Skip the 400,000-person waitlist at functionhealth.com/simonhill. Only available to those living in the United States. Eight Sleep Upgrade your sleep with the Pod 4 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF for $350 off at eightsleep.com/theproof. Try it risk-free for 30 days, with worldwide shipping. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to [Eimele.com](https://eimele.com/essential-8/15660280.html.) and use code SIMON at checkout for 10% off your first order. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Simon Hill, MSc, BSc (Hons) • Creator of theproof.com • Host of The Proof with Simon Hill • Author of The Proof is in the Plants Subscribe & Connect: • YouTube • Apple Podcasts • Spotify • Instagram: @simonhill • Twitter: @theproof • Facebook: The Proof with Simon Hill Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.

Transcribed - Published: 25 March 2025

In today’s episode, I’m joined by Drew Harrisberg, an exercise physiologist, diabetes educator, and founder of Drew’s Daily Dose. We dive into the science behind Apple Cider Vinegar (ACV)—does it actually help with blood sugar, weight loss, digestion, and overall health, or is it just another overhyped wellness trend? We also explore the power of anecdotes in the wellness industry, starting with Belle Gibson’s story and the new Netflix series on ACV. How can we separate fact from fiction when faced with bold health claims on social media? What we cover: • ACV and blood sugar – does it really help? • ACV and weight loss – what does the science say? • ACV vs. other blood sugar strategies (walking, fiber, etc.) • Potential downsides – acid, teeth damage, capsules, and more • How to take ACV without ruining your teeth • Should Simon take Bragg’s ACV as a sponsor? Ethics of podcast ads Later, Drew shares a moving tribute to his dog, Dennis, reflecting on grief, love, and celebrating life. We also talk about memory dividends and why showing up for the people (and pets) we love matters. We wrap up with a shocking magic trick, plenty of laughs, and a classic dad joke. Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family. This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Momentous My go-to supplement brand for protein and creatine is Momentous. Get 20% off your first purchase by using the code LIVINGPROOF at checkout at livemomentous.com Birch Sleep deeply and wake up refreshed with a Birch Natural Mattress, combining premium natural materials with unbeatable comfort. Rest easy with a 100-night trial and 25-year warranty. Get 20% off sitewide and 2 free Eco-Rest Pillows at birchliving.com/simonhill. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Follow [this link](https://eimele.com/essential-8/15660280.html.) for 20% off one-time purchases and subscriptions. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Simon Hill, MSc, BSc (Hons) • Creator of theproof.com • Host of The Proof with Simon Hill • Author of The Proof is in the Plants Subscribe & Connect: • YouTube • Apple Podcasts • Spotify • Instagram: @simonhill • Twitter: @theproof • Facebook: The Proof with Simon Hill Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.

Transcribed - Published: 17 March 2025

This episode originally aired on The Adversity Advantage, hosted by Doug Bopst—a personal trainer, author, and former addict who transformed his life through fitness. His podcast dives deep into health, mindset, and resilience to help people unlock their full potential. In our conversation, we break down the science of longevity, nutrition, and optimal health. We discuss the best dietary patterns for longevity, the debate around red meat and seed oils, and why exercise is essential for long-term health. Topics Covered: What does the science say about longevity and diet? Are seed oils really harmful, or is the science misunderstood? The real risks of red meat and saturated fats for long-term health How ultra-processed foods impact metabolic health The importance of protein intake for longevity and muscle preservation Why exercise is just as crucial as diet for healthspan The Living Proof Challenge – a zero-cost 12-week longevity program Join the Living Proof Challenge: theproof.com/livingproof You can connect with Doug through his Podcast Website, where he shares insightful conversations on health, fitness, and personal transformation. Follow him on Instagram for daily inspiration and expert advice, subscribe to his YouTube channel for in-depth discussions and interviews, and stay updated with his latest thoughts on X. Introduction (00:00) Discussing the Best Dietary Patterns for Longevity (00:53) Debating Meat-Based Diets and Long-Term Health (04:33) Health Implications of Red Meat Consumption (09:54) Practical Steps for Improved Health & Longevity (22:50) Understanding Amino Acids and Protein Sources (34:01) The Importance of Exercise for Longevity (34:50) Exercise Protocols for Optimal Health (35:47) Resistance Training and Its Benefits (37:43) Cardio and Resistance Training Balance (41:30) Intermittent Fasting and Meal Timing (52:40) The Role of Light and Circadian Rhythms (56:20) Insights on Longevity and Nutrition (59:47) The Importance of Relationships for Happiness (01:04:01) Conclusion (01:09:17) Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family. This episode is brought to you by: 38TERA Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Function Health Track, optimise, and thrive with Function Health. Access 100+ lab tests – five times more than a typical physical – including ApoB and LP(a), no doctor approval needed. Get science-backed insights and track your results over time. Skip the 400,000-person waitlist at functionhealth.com/simonhill. Only available to those living in the United States. Shopify Shopify, the world's leading e-commerce platform, helps you turn browsers into buyers with the internet’s best-converting check out–up to 36% better compared to other leading e-commerce platforms. To boost your conversion rate, and grow your business, sign up for a one-dollar-per-month trial period at shopify.com/proof. Simon Hill, MSc, BSc (Hons) • Creator of theproof.com • Host of The Proof with Simon Hill • Author of The Proof is in the Plants Subscribe & Connect: • YouTube • Apple Podcasts • Spotify • Instagram: @simonhill • Twitter: @theproof • Facebook: The Proof with Simon Hill Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.

Transcribed - Published: 11 March 2025

You may have heard claims that C:15 (pentadecanoic acid) is the first essential fat discovered in 90 years, a powerful longevity booster, and a game-changer for metabolic health. But how much of this is backed by solid science? In this episode, I sit down with Dr. Bill Harris, a leading expert in fatty acid research, to critically evaluate the evidence behind C:15. We break down the population studies linking it to health benefits, the key clinical trials testing its effects, and whether the marketing around Fatty15 is ahead of the actual data. In this episode, we cover: What exactly is C:15, and how does it compare to other fats? The claim that C:15 is an essential nutrient—does it meet the criteria? The current evidence on C:15 and its impact on cholesterol, glucose, and inflammation Does C:15 supplementation mimic omega-3s, metformin, or rapamycin? The broader issue of patenting a naturally occurring compound For more details and supporting studies, visit the full show notes. Introduction to Pentadecanoic Acid (C15) (00:00) Evaluating the Claims of C15 (02:05 Comparing C15 with Other Fatty Acids (03:12) Health Implications of Dairy Fats and the Essentiality of C15 (05:02) Scientific Evidence and Studies on C15 (13:12) Interpreting Clinical Trial Results, Cholesterol, and the Tango Trial (27:59) Cholesterol and the Tango Trial (28:28) Comparing C15 to Omega 3s (32:02) Future Research Directions for C15 (37:46) Longevity Claims and Patents (42:30) Final Thoughts and Conclusion (49:44) Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family. This episode is brought to you by: 38TERA Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Eight Sleep Upgrade your sleep with the Pod 4 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF for $350 off at eightsleep.com/theproof. Try it risk-free for 30 days, with worldwide shipping. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to [Eimele.com](https://eimele.com/essential-8/15660280.html.) and use code SIMON at checkout for 10% off your first order. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Simon Hill, MSc, BSc (Hons) • Creator of theproof.com • Host of The Proof with Simon Hill • Author of The Proof is in the Plants Subscribe & Connect: • YouTube • Apple Podcasts • Spotify • Instagram: @simonhill • Twitter: @theproof • Facebook: The Proof with Simon Hill Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.

Transcribed - Published: 3 March 2025

You may have heard claims that C15:0 (pentadecanoic acid) is the first essential fat discovered in 90 years, a powerful longevity booster, and a game-changer for metabolic health. But how much of this is backed by solid science? In this episode, I sit down with Dr. Bill Harris, a leading expert in fatty acid research, to critically evaluate the evidence behind C15:0. We break down the population studies linking it to health benefits, the key clinical trials testing its effects, and whether the marketing around Fatty15 is ahead of the actual data. In this episode, we cover: What exactly is C15:0, and how does it compare to other fats? The claim that C15:0 is an essential nutrient—does it meet the criteria? The current evidence on C15:0 and its impact on cholesterol, glucose, and inflammation Does C15:0 supplementation mimic omega-3s, metformin, or rapamycin? The broader issue of patenting a naturally occurring compound For more details and supporting studies, visit the full show notes. Introduction to Pentadecanoic Acid (C15:0) (00:00) Evaluating the Claims of C15:0 (02:05 Comparing C15:0 with Other Fatty Acids (03:12) Health Implications of Dairy Fats and the Essentiality of C15:0 (05:02) Scientific Evidence and Studies on C15:0 (13:12) Interpreting Clinical Trial Results, Cholesterol, and the Tango Trial (27:59) Cholesterol and the Tango Trial (28:28) Comparing C15:0 to Omega 3s (32:02) Future Research Directions for C15:0 (37:46) Longevity Claims and Patents (42:30) Final Thoughts and Conclusion (49:44) Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family. This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout.  Eight Sleep Upgrade your sleep with the Pod 4 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF for $350 off at eightsleep.com/theproof. Try it risk-free for 30 days, with worldwide shipping. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Follow this link for 20% off one-time purchases and subscriptions. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Simon Hill, MSc, BSc (Hons) • Creator of theproof.com • Host of The Proof with Simon Hill • Author of The Proof is in the Plants Subscribe & Connect: • YouTube • Apple Podcasts • Spotify • Instagram: @simonhill • Twitter: @theproof • Facebook: The Proof with Simon Hill Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.

Transcribed - Published: 3 March 2025

Is olive oil really as healthy as people claim? How does it compare to other fats? And how do you choose the best product for cooking and everyday use? In this episode, I take a deep dive into the science behind olive oil—its potential role in longevity, its impact on chronic diseases like cardiovascular disease and diabetes, and the key factors that determine quality. In this episode, we cover: Olive oil’s role in longevity and overall health The difference between refined and extra virgin olive oil How olive oil may influence cardiovascular, cognitive, and metabolic health What to look for when buying olive oil and how to store it properly Whether it’s safe to cook with olive oil and how to preserve its benefits For more details and supporting studies, visit the full show notes. Introduction (00:00) Olive Oil for Longevity and Lifespan (00:52) Olive Oil for Heart Health and Chronic Disease (06:28) Olive Oil’s Role in Cancer Prevention (07:58) Olive Oil for Brain Health and Cognitive Function (12:38) Olive Oil for Metabolic Health and Blood Sugar Control (16:08) How Olive Oil Supports Overall Health (21:12) How to Choose High-Quality Olive Oil (25:27) Best Practices for Cooking and Storing Olive Oil (35:12) Key Takeaways on Olive Oil’s Health Benefits (41:32) Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family. This episode is brought to you by: 38TERA Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Function Health Track, optimise, and thrive with Function Health. Access 100+ lab tests – five times more than a typical physical – including ApoB and LP(a), no doctor approval needed. Get science-backed insights and track your results over time. Skip the 400,000-person waitlist at functionhealth.com/simonhill. Only available to those living in the United States. Pique Tea Pique's Nandaka provides sustainable, all-day energy and makes you feel like you’re doing something good for your body! Try Pique and get 20% off plus a FREE starter kit when you shop exclusively at Piquelife.com/simon. Calm Find your calm anytime, anywhere with Calm, the #1 app for meditation and relaxation. From guided meditations to sleep stories and breathing exercises, Calm helps you reduce stress, improve focus, and sleep better. Visit calm.com/proof for 40% off a premium subscription today. Applied Nutrition Literacy Looking to sharpen your nutrition literacy and make smarter, science-based decisions? Enrol in the Applied Nutrition Literacy Course to gain the tools you need to evaluate research confidently. Perfect for nutrition professionals and keen enthusiasts. Join by March 8 here. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to [Eimele.com](https://eimele.com/essential-8/15660280.html.) and use code SIMON at checkout for 10% off your first order. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Simon Hill, MSc, BSc (Hons) • Creator of theproof.com • Host of The Proof with Simon Hill • Author of The Proof is in the Plants Subscribe & Connect: • YouTube • Apple Podcasts • Spotify • Instagram: @simonhill • Twitter: @theproof • Facebook: The Proof with Simon Hill Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.

Transcribed - Published: 25 February 2025

In this episode, I sit down with Drew Harrisberg to break down four new studies covering selenium intake, plant vs. animal monounsaturated fats, workout recovery strategies, and resistance training techniques. But beyond the science, we also discuss a critical issue in health communication—the responsibility of podcast hosts when platforming health claims. Using recent episodes of Diary of a CEO featuring Dr. Mindy Pelz and Dr. Sarah Berry, we examine how misinformation spreads, why extreme views persist, and how listeners can differentiate science from pseudoscience. Introduction (00:00) Ross Walker: The Comedian Cardiologist (03:23)\ The Importance of CGM and Misleading Health Advice (12:29) Scientific Method and Logical Consistency (24:29) Debunking Myths: Seed Oils and Health (32:59) The Power of Anecdotes vs. Scientific Evidence (42:54) Jordan Peterson and Elon Musk's Viral Clip (50:13) Personal Humility and Dietary Failures (53:07) Study on Recovery Modalities: Hot vs. Cold Baths (01:00:56) Minimum Effective Dose for Resistance Training (01:19:34) Selenium Intake and Brazil Nuts (01:31:14) Monounsaturated Fats and Type 2 Diabetes Risk (01:48:32) Concluding Thoughts (02:21:01) Key Discussion Points: Dr. Sarah Berry’s Diary of a CEO appearance and the backlash The seed oil controversy—do they really cause inflammation? How to spot red and green flags in health claims Four new studies on nutrition and exercise, including whether training to failure is necessary for muscle growth For more details and supporting studies, visit the full show notes: https://theproof.com/podcast/ The best way to support the show is to use the products and services offered by our sponsors. Visit http://theproof.com/friends for exclusive discounts. This episode is brought to you by: 38TERA Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Eight Sleep Upgrade your sleep with the Pod 4 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF for $350 off at eightsleep.com/theproof. Try it risk-free for 30 days, with worldwide shipping. Calm Find your calm anytime, anywhere with Calm, the #1 app for meditation and relaxation. From guided meditations to sleep stories and breathing exercises, Calm helps you reduce stress, improve focus, and sleep better. Visit calm.com/proof for 40% off a premium subscription today. Function Health Track, optimise, and thrive with Function Health. Access 100+ lab tests – five times more than a typical physical – including ApoB and LP(a), no doctor approval needed. Get science-backed insights and track your results over time. Skip the 400,000-person waitlist at functionhealth.com/simonhill. Only available to those living in the United States. Momentous My go-to supplement brand for protein and creatine is Momentous. Get 20% off your first purchase by using the code LIVINGPROOF at checkout at livemomentous.com Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to [Eimele.com](https://eimele.com/essential-8/15660280.html.) and use code SIMON at checkout for 10% off your first order. Simon Hill, MSc, BSc (Hons) Creator of theproof.com Host of The Proof with Simon Hill Author of The Proof is in the Plants Subscribe & Connect: YouTube Apple Podcasts Spotify Instagram: @simonhill Twitter: @theproof Facebook: The Proof with Simon Hill Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.

Transcribed - Published: 18 February 2025

In today’s episode of The Proof, we dissect a video featuring Dr. Gabrielle Lyon discussing protein sources and the importance of leucine for muscle building. I break down her claims, compare animal and plant protein sources, and explore the latest research on muscle protein synthesis and long-term health outcomes. Introduction (00:00) Dr. Lyon's Argument: Animal vs. Plant Protein (00:17) Critiquing Dr. Lyon's Protein Source Comparisons (01:14) Evaluating the Leucine Threshold Hypothesis (03:13) Plant-Based Protein Sources: A Deeper Look (06:30) Scientific Studies on Protein and Muscle Growth (15:40) Conclusion (25:17) Key Discussion Points: Dr. Lyon’s Claims Comparing Protein Sources The Leucine Threshold Debate Beyond Muscle Protein Synthesis Plus, if you watch/listen all the way to the end I share a fun personal story about my 90-year-old grandma who took up walking 10km a day! Enjoy, Simon Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family. This episode is brought to you by: 38TERA Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Calm Find your calm anytime, anywhere with Calm, the #1 app for meditation and relaxation. From guided meditations to sleep stories and breathing exercises, Calm helps you reduce stress, improve focus, and sleep better. Visit calm.com/proof for 40% off a premium subscription today. Function Health Track, optimise, and thrive with Function Health. Access 100+ lab tests – five times more than a typical physical – including ApoB and LP(a), no doctor approval needed. Get science-backed insights and track your results over time. Skip the 400,000-person waitlist at functionhealth.com/simonhill. Only available to those living in the United States. Shopify Shopify, the world's leading e-commerce platform, helps you turn browsers into buyers with the internet’s best-converting check out–up to 36% better compared to other leading e-commerce platforms. To boost your conversion rate, and grow your business, sign up for a one-dollar-per-month trial period at shopify.com/proof. Pique Tea Pique's Nandaka provides sustainable, all-day energy and makes you feel like you’re doing something good for your body! Try Pique and get 20% off plus a FREE starter kit when you shop exclusively at Piquelife.com/simon. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com and use code SIMON at checkout for 10% off your first order. Simon Hill, MSc, BSc (Hons) • Creator of theproof.com • Host of The Proof with Simon Hill • Author of The Proof is in the Plants Subscribe & Connect: • YouTube • Apple Podcasts • Spotify • Instagram: @simonhill • Twitter: @theproof • Facebook: The Proof with Simon Hill Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.

Transcribed - Published: 11 February 2025

Think creatine supplementation is all about timing and loading? You might be surprised. In episode #350, I dive into six frequently asked questions about creatine, inspired by a follow-up review by Dr. Jose Antonio and colleagues. Whether you’re just starting with creatine or already supplementing, this episode will provide clarity and practical insights. Learn why timing matters less than consistency, whether co-supplements like carbs enhance effectiveness, and if creatine affects blood pressure, fertility, or urine production. This is your ultimate guide to making informed decisions about creatine supplementation. Key highlights include: Does the timing of creatine intake matter? Do other compounds enhance creatine’s effectiveness? Does creatine affect blood pressure or increase urine production? Is creatine safe to use during pregnancy? Can creatine supplementation impact male fertility? Discover insights and supporting studies in the full show notes. Introduction (00:00) Timing of Creatine Supplementation (02:50) Enhancing Creatine Effectiveness with Other Compounds (05:06) Creatine and Blood Pressure (06:31) Creatine and Urine Production (08:35) Creatine Safety During Pregnancy (10:56) Creatine and Male Fertility (12:49) Recap and Final Thoughts (14:37) Outro (17:12) This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Function Health Track, optimise, and thrive with Function Health. Access 100+ lab tests – five times more than a typical physical – including ApoB and LP(a), no doctor approval needed. Get science-backed insights and track your results over time. Skip the 400,000-person waitlist at functionhealth.com/simonhill. Only available to those living in the United States. Eight Sleep Upgrade your sleep with the Pod 4 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF for $350 off at eightsleep.com/theproof. Try it risk-free for 30 days, with worldwide shipping. Calm Find your calm anytime, anywhere with Calm, the #1 app for meditation and relaxation. From guided meditations to sleep stories and breathing exercises, Calm helps you reduce stress, improve focus, and sleep better. Visit calm.com/proof for 40% off a premium subscription today. Pique Tea Pique's Nandaka provides sustainable, all-day energy and makes you feel like you’re doing something good for your body! Try Pique and get 20% off plus a FREE starter kit when you shop exclusively at Piquelife.com/simon. Notion Notion is the all-in-one workspace that helps you organise your work and life seamlessly. It’s been the backbone of The Proof since 2018, streamlining everything from guest bios and show notes to managing episodes. With Notion AI, you can take your productivity to the next level—generate ideas, summarise content, and organise tasks effortlessly. Try Notion for free at notion.com/theproof and experience the difference for yourself! Simon Hill, MSc, BSc (Hons) Creator of theproof.com Host of The Proof with Simon Hill Author of The Proof is in the Plants Subscribe & Connect: YouTube Apple Podcasts Spotify Instagram: @simonhill Twitter: @theproof Facebook: The Proof with Simon Hill Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.

Transcribed - Published: 3 February 2025

In this episode of The Proof, I explore male fertility with Dr. Ramy Abou Ghayda, a leading urologist specialising in reproductive health. Together, we unpack the science behind sperm health, bust common myths, and provide evidence-based strategies for optimising male fertility. You'll discover: The truth about declining male fertility rates and what current research tells us How lifestyle factors like diet, exercise, and environmental toxins affect sperm health Evidence-based nutrition strategies and supplements for improving fertility Whether you should abstain from ejaculation in the days before intercourse when trying to conceive The impact of modern technology and daily habits on reproductive health Practical tips for protecting and enhancing male fertility at any age And much more Whether you're planning a family or simply interested in optimising your reproductive health, this conversation offers valuable insights and actionable advice from one of the field's leading experts. Introduction (00:00) Is Declining Male Fertility a Real Concern? (00:08) Understanding Semen Health and Fertility Basics (01:37) Breaking the Taboo: Male Infertility in Society (04:37) What Affects Male Fertility? Lifestyle, Environment, and More (09:14) Semen Analysis and Testing: Lab vs. Home Kits (18:18) Environmental Toxins, Lifestyle, and Fertility (23:31) Sperm Testing Options (30:50) Testosterone Therapy and Sperm Freezing (40:30) Lifestyle Changes to Boost Fertility (57:46) How Medications Affect Sperm and Erectile Function (01:12:34) Viagra, Cialis, and Psychological Aspects of Fertility (01:19:52) Timing Conception and the Fertile Window (01:24:24) Sleep’s Role in Male Fertility (01:36:31) Medical Interventions and Future Research (01:38:04) Future of Male Fertility Research and Innovations (01:45:27) Final Takeaways and Myths in Male Fertility (01:59:00) This episode is brought to you by: Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com and use code SIMON at checkout for 10% off your first order. 38TERA Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. LMNT LMNT’s Chocolate Medley is back. A variety pack of choc mint, choc chai, and choc raspberry electrolytes for proper hydration. Stay hydrated with LMNT. Receive a free LMNT sample pack with any order when you purchase via drinklmnt.com/simon. Eight Sleep Upgrade your sleep with the Pod 4 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF for $350 off at eightsleep.com/theproof. Try it risk-free for 30 days, with worldwide shipping. NordVPN Protect your personal data and browse with confidence using NordVPN. With fast servers and advanced encryption, NordVPN protects you – even on public Wi-Fi – and unlocks content worldwide. EXCLUSIVE NordVPN Deal ➼ https://nordvpn.com/theproof. Try it risk-free with a 30-day money-back guarantee. Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family. Simon Hill, MSc, BSc (Hons) Creator of theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants Watch the episodes on YouTube or listen on Apple/Spotify

Transcribed - Published: 20 January 2025

In this episode of The Proof, I explore male fertility with Dr. Ramy Abou Ghayda, a leading urologist specialising in reproductive health. Together, we unpack the science behind sperm health, bust common myths, and provide evidence-based strategies for optimising male fertility. You'll discover: The truth about declining male fertility rates and what current research tells us How lifestyle factors like diet, exercise, and environmental toxins affect sperm health Evidence-based nutrition strategies and supplements for improving fertility Whether you should abstain from ejaculation in the days before intercourse when trying to conceive The impact of modern technology and daily habits on reproductive health Practical tips for protecting and enhancing male fertility at any age And much more Whether you're planning a family or simply interested in optimising your reproductive health, this conversation offers valuable insights and actionable advice from one of the field's leading experts. Introduction (00:00) Is Declining Male Fertility a Real Concern? (00:08) Understanding Semen Health and Fertility Basics (01:37) Breaking the Taboo: Male Infertility in Society (04:37) What Affects Male Fertility? Lifestyle, Environment, and More (09:14) Semen Analysis and Testing: Lab vs. Home Kits (18:18) Environmental Toxins, Lifestyle, and Fertility (23:31) Sperm Testing Options (30:50) Testosterone Therapy and Sperm Freezing (40:30) Lifestyle Changes to Boost Fertility (57:46) How Medications Affect Sperm and Erectile Function (01:12:34) Viagra, Cialis, and Psychological Aspects of Fertility (01:19:52) Timing Conception and the Fertile Window (01:24:24) Sleep’s Role in Male Fertility (01:36:31) Medical Interventions and Future Research (01:38:04) Future of Male Fertility Research and Innovations (01:45:27) Final Takeaways and Myths in Male Fertility (01:59:00) This episode is brought to you by: Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com and use code SIMON at checkout for 10% off your first order. 38TERA Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. LMNT LMNT’s Chocolate Medley is back. A variety pack of choc mint, choc chai, and choc raspberry electrolytes for proper hydration. Stay hydrated with LMNT. Receive a free LMNT sample pack with any order when you purchase via drinklmnt.com/simon. Eight Sleep Upgrade your sleep with the Pod 4 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF for $350 off at eightsleep.com/theproof. Try it risk-free for 30 days, with worldwide shipping. NordVPN Protect your personal data and browse with confidence using NordVPN. With fast servers and advanced encryption, NordVPN protects you – even on public Wi-Fi – and unlocks content worldwide. EXCLUSIVE NordVPN Deal ➼ https://nordvpn.com/theproof. Try it risk-free with a 30-day money-back guarantee. Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family. Simon Hill, MSc, BSc (Hons) Creator of theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants Watch the episodes on YouTube or listen on Apple/Spotify

Transcribed - Published: 20 January 2025