Women's Brain Health: Environment, Hormones, Menopause & Neuronal Pruning with Dr. Sarah McKay
The Resetter Podcast with Dr. Mindy
Dr. Mindy Pelz
4.8 • 1.1K Ratings
🗓️ 27 October 2025
⏱️ 99 minutes
🧾️ Download transcript
Summary
Dr. Sarah McKay, a brilliant neuroscientist, takes us on a thrilling adventure into the intricate dance between hormones and the female brain during menopause. She shares her personal quest to unravel how those mischievous hormonal shifts tweak women's brains from 40 onwards, revealing the fascinating secrets of neuronal 'pruning and tuning.' Dr. McKay also shines a spotlight on the superstars estrogen, dopamine, and serotonin, and uncovers how our social circles and daily choices play a massive role in brain health. With sparkling discussions on metabolic health and the wider ripple effect of menopause, this episode is a must-listen for any woman eager to keep her brain sparkling and sharp!
To view full show notes, more information on our guests, resources mentioned in the episode, discount codes, transcripts, and more, visit https://drmindypelz.com/ep311
Dr. Sarah McKay is a neuroscientist and science communicator who makes brain science practical and accessible for better health, wellbeing, and performance. She holds an MSc and PhD from Oxford and spent five years researching spinal cord injury before founding Think Brain, her science education company. Sarah's appeared on ABC's Catalyst, The Mel Robbins Podcast, SBS Insight, and has been featured in The Wall Street Journal, The Guardian, and Australian Women's Weekly. She's the author of The Women's Brain Book, Baby Brain, and Brain Health for Dummies, all exploring how understanding the brain can help us live and feel better.
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Transcript
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| 0:00.0 | On this episode of the Resetter podcast, I bring you Dr. Sarah Mackay. |
| 0:09.0 | Woo, you ready for some neuroscience? |
| 0:12.0 | This is so good. |
| 0:13.0 | And let me just kind of cue up what you're going to hear because I think your mind is going |
| 0:19.0 | to be blown. |
| 0:20.0 | First, I've not met another human that loves neuroscience more than I do, |
| 0:27.0 | but I would say that Dr. Sarah Mackay may have 10 times to me. |
| 0:32.1 | Now, she committed her whole career to this, |
| 0:35.1 | but if you look at her Instagram, which I highly recommend you go and look at, |
| 0:39.3 | she has combined neuroscience. She is an official neuroscientist with women's health. |
| 0:45.8 | And her focus is really helping us all understand the female brain. I love that she has on her Instagram. She calls |
| 0:55.8 | herself a science communicator, and she absolutely is that. And she is the author, a three-time author, |
| 1:03.5 | but the most interesting one that she has brought forward is called the Women's Brain Book. |
| 1:09.7 | And she just redid the, she did a second edition |
| 1:14.1 | with new information in it. So what I wanted to bring Sarah to you all for is to, again, |
| 1:20.9 | help us understand these brain changes that are going on after 40 as our hormones shift. |
| 1:27.2 | And you've heard me talk a lot about Lisa Moscone. |
| 1:29.9 | I did an interview with her about a year and a half ago. |
| 1:33.4 | You've heard me talk about my new book, Age Like a Girl, |
| 1:35.8 | which is all about the rewiring of your brain for the positive. |
| 1:40.1 | And now you're gonna hear the nerdy scientist, |
| 1:43.1 | and I promise you it's going to be entertaining. |
... |
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