Welcome to the Brain Health Revolution podcast with your hosts, Aisha and Dean Shurzai.

This episode is a part of a live recording for our Neuroacademy community, and the topic of the discussion is the genetics of Alzheimer's disease, in particular a deep dive

into apolypo-liproteen E-4 or APO-E4 gene, which is the most influential genetic risk factor

associated with late-onset Alzheimer's disease.

We describe the evolutionary aspects of apolyp-p proteins, how they're produced,

how the different isoforms of APO-E influence the different factors leading to Alzheimer's disease,

how it affects lipid metabolism and immune function in the brain, and what is the latest evidence on

the epigenetics of APO-E4?

Typically, the community members post their questions ahead of time, and we structure the

conversation in a way to address their questions, and we also answer their questions live

during the recording.

Now, before we jump into the conversation, a little bit about Neuro Academy.

Neuroacademy is a membership-based online community with over 700 active members,

with resources to achieve optimal brain health, better cognition, and prevent cognitive decline.

The platform provides the opportunity to connect with us and an empowering community and participate in weekly live Q&A sessions,

education on evidence-based nutrition and other lifestyle factors, live cooking demonstrations, live podcasts and Q&A with remarkable help leaders,

interest groups, book clubs, science club discussions,

access to on-demand courses on prevention of neurological diseases,

evidence-based nutrition and cooking, behavioral science, and many other topics related to brain health.

Members can receive CE or CME credits and certification after taking the courses.

Join us by visiting neuroacademy.com.

Now, let's dive into the conversation.

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