Shifting Perspectives: Hormone Replacement Therapy, Menopause, and the Dementia Dialogue
The Brain Health Revolution Podcast
Dean and Ayesha Sherzai
4.8 • 604 Ratings
🗓️ 21 July 2023
⏱️ 53 minutes
🧾️ Download transcript
Summary
In this episode, we explore the connection between hormone replacement therapy and dementia risk, the impact of hormones on brain development and resilience throughout life, and the critical considerations for individuals undergoing pre- and post-menopause in terms of brain health.
Specifically, we delve into a recent scientific article suggesting that menopausal hormone replacement therapy heightens the risk of dementia in a Danish population. We illuminate the intricate relationship between hormones, lifestyle risk factors, and brain health.
Reference:
Pourhadi, N., Mørch, L. S., Holm, E. A., Torp-Pedersen, C., & Meaidi, A. (2023). Menopausal hormone therapy and dementia: nationwide, nested case-control study. bmj, 381.
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Transcript
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| 0:00.0 | Welcome to the Brain Health Revolution podcast with your hosts, Aisha and Dean Cherzai. |
| 0:11.4 | We are neurologists, scientists, and authors of two best-selling books and parents to two amazing humans. |
| 0:18.1 | In a world where our understanding of brain health is constantly evolving, |
| 0:22.5 | join us as we unravel the mysteries of the human brain. Through captivating conversations, |
| 0:28.3 | insightful interviews, and thought-provoking discussions, we empower you with the knowledge and |
| 0:33.7 | tools to optimize brain function and prevent cognitive decline. |
| 0:38.0 | From nutrition, exercise, restorative sleep to building cognitive resilience and the impact |
| 0:44.0 | of technology, we explore the fascinating connections between brain health and other facets of our |
| 0:50.0 | lives. Get ready to unlock the potential of your brain and embrace a life of vitality. Thank you for |
| 0:57.0 | listening. Welcome, everyone. Thank you so much for joining us today. We will talk about hormone |
| 1:03.1 | therapy and Alzheimer's risk, and we wanted to speak about this subject, particularly because |
| 1:10.0 | recently a paper was published in the British |
| 1:13.0 | Medical Journal that showed that when women are on hormone replacement therapy, they may be at |
| 1:20.0 | a higher risk of developing Alzheimer's disease. Now this topic, the hormone therapy and its |
| 1:26.1 | relationship with the development or prevention of |
| 1:28.5 | Alzheimer's disease is a very complex one. And there's been a lot of contradictory information |
| 1:33.4 | over the years. So we wanted to take some time to discuss the importance of hormone therapy |
| 1:39.2 | during menopause and, you know, post-menopausal era. And we also wanted to kind of take a deep dive into, |
| 1:45.8 | you know, the disparities that men and women have as far as risk of Alzheimer's disease is concerned. |
| 1:51.9 | We wanted to touch on the effect of sex hormones during the different stages of life on brain and |
| 1:57.6 | brain health. We also wanted to discuss some of the evidence from the different |
| 2:02.1 | studies that look at the risk of development of neurodegenerative diseases in women who are |
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