TWiV 993: COVID-19 drives autoimmunity

This Week in Virology

Vincent Racaniello

Vincent, Microbe, Medicine, Microbiology, Racaniello, Infection, Virus, Virology, Pathogen, Infectious, Twiv, Science & Medicine

4.8 • 2.2K Ratings

🗓️ 19 March 2023

⏱️ 108 minutes

🔗️ Recording | iTunes | RSS

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Summary

TWiV reveals how treatment with remdesivir for COVID-19 resolved a chronic poliovirus infection in an immunocompromised patient, and the finding that infection with SARS-CoV-2 leads to an increase in new and preexisting autoantibodies. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode •Register for ASV 2023 •MicrobeTV Discord Server •Janet Sinsheimer on TWiV 653 •Clearance of chronic poliovirus infection by remdesivir (Front Immunol) •Autoimmunity induced by SARS-CoV-2 infection (Nat Comm) •Letters read on TWiV 993 •Timestamps by Jolene. Thanks! Weekly Picks Brianne – Xkcd: Lymphocytes Kathy – A brief history of Parafilm with video Alan – Mapping and exploring the USS Monitor wreck Vincent – Skype a Scientist Intro music is by Ronald Jenkees Send your virology questions and comments to [email protected]

Transcript

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0:00.0	This week in virology, the podcast about viruses, the kind that make you sick.
0:10.4	From microbe TV, this is TWIV, this week in virology, episode 993 recorded on March 17th, 2023.
0:21.8	I'm Vincent Racken-Yellow and you're listening to the podcast, All About Viruses.
0:27.2	Joining me today from Ann Arbor, Michigan, Kathy Spindler.
0:31.4	Hi everybody. Here it's four degrees Celsius with a fresh breeze from the west and in
0:40.8	Fahrenheit, that's 37.
0:43.9	I just saw Kathy in Atlanta for a TWIV we did at the APHL IDCon. I'm not going to tell you
0:50.7	what those letters mean. You have to wait and see, but it was a good one. Very good.
0:55.8	Also joining us from Madison, New Jersey, Brienne Barker.
0:59.5	Hi, great to be here. It is 60 degrees Fahrenheit, 16 Celsius here, and very, very gray.
1:08.0	I think it's similar to what we have here. 14C, cloudy, yep.
1:14.9	This looks like a little rain in the forecast. You have rain in yours?
1:18.6	I do have rain in mine.
1:20.2	Also joining us from Western Massachusetts, Alan Dove.
1:23.7	Good to be here. It's 50 Fahrenheit, 10C. I guess Kathy is now using the Beaufort wind scale.
1:31.0	So I'll say we have a light breeze. A fresh breeze would be 15 to 20 knots, I think.
1:37.2	We've got west at about five knots.
1:41.3	I used whatever the Norwegian weather app had.
1:45.8	Let's see what they say about wind on the other app, 20 miles per hour.
1:50.0	That's a fresh breeze, of course.
1:51.2	Yeah, gusts to 34.
1:54.6	With four people, we have a nice square, it's all symmetrical.
	...

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