TWiV 889: COVID-19 clinical update #110 with Dr. Daniel Griffin

This Week in Virology

Vincent Racaniello

Vincent, Microbe, Medicine, Microbiology, Racaniello, Infection, Virus, Virology, Pathogen, Infectious, Twiv, Science & Medicine

4.8 • 2.2K Ratings

🗓️ 16 April 2022

⏱️ 53 minutes

🔗️ Recording | iTunes | RSS

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Summary

In COVID-19 clinical update #110, Dr. Griffin covers hospital admissions during variant outbreaks, viral load in vaccinated and unvaccinated individuals, predictive capacity of symptoms in children, comparison of antigen tests, incidence of myocarditis after vaccination, steroids during replication phase, Paxlovid efficacy and safety, fluvoxamine, sabizabutin, colchicine, and prevalence of infection in Africa. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Hospital admissions during Omicron and Delta variant outbreaks (Lancet) Viral load in unvaccinated and vaccinated individuals (Nat Med) Predictive Capability of symptoms in children (Clin Inf Dis) Comparison of antigen tests (medRxiv) Incidence of Myocarditis after COVID19 and non-COVID19 vaccination (Lancet) Steroids during viral replication phase (Resp) Paxlovid efficacy and safety (Pfizer) Fluvoxamine & Outpatient Management (JAMA) Sabizabutin efficacy and safety (Veru) Colchicine and lack of benefit (Lancet) SARS-CoV-2 prevalence in Africa (medRxiv) Contribute to ASTMH fundraiser at PWB Dr. Griffin’s treatment guide (pdf) Letters read on TWiV 889 33:35 Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to [email protected]

Transcript

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0:00.0	This week in virology, the podcast about viruses, the kind that make you sick.
0:10.6	From microbe TV, this is TWIV, this week in virology. Episode 889 recorded on April 14,
0:20.0	2020-22. I'm Vincent Rackenhello and you're listening to the podcast all about viruses.
0:26.3	Joining me today right here at the incubator, Daniel Griffin.
0:30.9	Hello everyone. Good to see you here in person, Daniel.
0:34.6	That's nice to be here in person. Yeah, and we have a lot to talk about today. Can you imagine that?
0:41.1	All right, well it's update number 110. Let's have it.
0:44.1	All right, let me start with our quotation because we've got a lot to cover. So,
0:48.1	anti-intellectualism has been a constant thread winding its way through our political and cultural life.
0:55.6	Nurtured by the false notion that democracy means my ignorance is just as good as your knowledge.
1:02.7	And that was Isaac Asimov and what could he possibly have been talking about?
1:08.4	As far as updates, we are seeing a rise in the number of cases in our immediate tri-state area.
1:15.2	Hour seven day average here in New York is already approaching 6,000 new cases per day.
1:21.2	This is already higher than it ever was during the Delta wave, so just to give people perspective.
1:26.7	I'm going to sort of close with a little bit of words of warning about behavior around the holidays.
1:31.6	Because I don't know Vincent, there's this rumor that this is nothing to do with behavior and it's
1:36.4	all very driven, but I am going to challenge that and suggest that we have some control here and
1:42.1	there's choices we can make to keep ourselves in our love to one safe during the holidays that
1:47.7	a lot of people will be enjoying when they listen to that. Daniel, what are these tests for?
1:53.6	Are they in people with symptoms or are they random screening tests? Do we know?
2:01.0	So it's a mix and I do get some sort of on the ground real-time data out of our urgent care
2:08.8	centers, about a hundred of those in the tri-state area, just sort of pro-health, riverside,
	...

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