TWiV 1036: Clinical update with Dr. Daniel Griffin

This Week in Virology

Vincent Racaniello

Vincent, Microbe, Medicine, Microbiology, Racaniello, Infection, Virus, Virology, Pathogen, Infectious, Twiv, Science & Medicine

4.8 • 2.2K Ratings

🗓️ 19 August 2023

⏱️ 40 minutes

🔗️ Recording | iTunes | RSS

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Summary

In his weekly clinical update, Dr. Griffin discusses Florida local transmission of dengue cases reported in Broward and Miami-Dade counties, infants admitted to US intensive care units for RSV infection during the 2022 seasonal peak, long-term risk of death and readmission after hospital admission with COVID-19 among older adults, safety profile and clinical and virological outcomes of Nirmatrelvir-Ritonavir treatment in patients with advanced chronic kidney disease and COVID-19, Fluvoxamine vs placebo for outpatients with symptomatic COVID-19, the effect of corticosteroids, antibiotics, and anticoagulants on the development of post-COVID-19 syndrome in COVID-19 hospitalized patients 6 months after discharge, long COVID and significant activity limitation among adults, incidence of diabetes following COVID-19 vaccination and SARS-CoV-2 infection in Hong Kong, and diabetes following SARS-CoV-2 infection: Incidence, persistence, and implications of COVID-19 vaccination. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Florida local transmission of dengue cases (Outbreak News) Infants admitted to US ICU for RSV infection (JAMA) Long term risk of death and readmission after hospital admission with COVID-19 (BMJ) Outcomes of Nirmatrelvir-Ritonavir Treatment in patients with Kidney disease and COVID-19 (CID) Fluvoxamine vs placebo for outpatients with symptomatic COVID-19 (OFID) The effect of corticosteroids, antibiotics, and anticoagulants on the development of post-COVID-19 syndrome in hospitalized patients (CEM) Long COVID and significant activity limitation among adults (CDC) Incidence of Diabetes following COVID-19 vaccination and SARS-CoV-2 infection (PLOS) Diabetes following SARS-CoV-2 infection (BMJ) Contribute to our Floating Doctors fundraiser at PWB Letters read on TWiV 1036 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to [email protected]

Transcript

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0:00.0	This week in virology, the podcast about viruses, the kind that make you sick.
0:10.5	From microbe TV, this is TWIV, this week in virology, episode 1036, recorded on August 17th,
0:20.8	2023. I'm Vincent Draghaniello, and you're listening to the podcast, all about viruses.
0:28.0	Joining me today from New York, Daniel Griffin.
0:32.4	Hello, everyone. Daniel, cases of COVID still going up in the New York area.
0:38.8	They actually definitely are. The cases, the percent positivity, the hospitalizations, it's all
0:46.5	on the way up. It's not going down. So it's interesting, it's August. And so what do you think
0:52.8	are they going to continue to rise through the winter? Are they going to go down and then go back
0:56.8	up again in the winter? What's going on here? Yeah, I love predicting the future.
1:03.3	So no, I think people always say it's the hardest thing to predict. Maybe that was just
1:07.1	Joe Geepera. But we're actually, we should have some sense in our specialty. The weatherman
1:14.1	is wrong a lot, but they're not always wrong. And we would expect it to go up, go down a little
1:20.0	bit, and then we'll see our major search December January, because this is a respiratory pathogen,
1:26.5	and it is influenced by human behavior. So it's been really hot lately. As people may have
1:32.3	been aware, a lot of people are indoors. You go somewhere to eat at a restaurant. No one's
1:36.9	sitting outside right there, all packed inside, a lot of vacations. So there's a lot of
1:43.2	behavioral things that are going on. Don't worry, there's some people that are blaming it on,
1:47.6	the newest variant, but I will always attribute human behavior. What about flu? Does flu go up in
1:56.0	August? So it really does. And part of it is you need kind of a background level and flu. I mean,
2:02.4	flu is fascinating. And usually there are new variants that come out of certain parts of the
2:07.6	world. But then once they get in a certain level, then it is again behavior, right? So we see
2:14.3	surges sometimes right around Thanksgiving, right around the sort of end of December. Maybe
	...

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