TWiV 1035: Poxvirus wars, warp speed COVID-19 vaccine rollout

This Week in Virology

Vincent Racaniello

Vincent, Microbe, Medicine, Microbiology, Racaniello, Infection, Virus, Virology, Pathogen, Infectious, Twiv, Science & Medicine

4.8 • 2.2K Ratings

🗓️ 13 August 2023

⏱️ 121 minutes

🔗️ Recording | iTunes | RSS

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Summary

TWiV dissects a study of COVID-19 vaccination which shows that the timing of initial rollout affects disease outcomes more substantially than final coverage or degree of socioeconomic disparity, and discovery of a novel cellular defense comprising a nuclease that is activated by poxvirus infection and cleaves a specific tRNA molecule to inhibit protein synthesis. Hosts: Vincent Racaniello, Rich Condit, Alan Dove, and Brianne Barker Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Research assistant position in Rosenfeld Lab CBER/FDA (pdf) Impact of COVID-19 vaccination trends (Sci Adv) Poxvirus-activated anticodon nuclease (Sci Adv) Letters read on TWiV 1035 Timestamps by Jolene. Thanks! Weekly Picks Brianne – Project Hail Mary Rich – Bird Buddy Alan – Blood, Sweat, and Pixels and Press Reset Vincent – Are microplastics spreading infectious disease? Listener Picks Tom – Henrietta Lacks family settles lawsuit Kathleen – Why Insect Memories May Not Survive Metamorphosis Intro music is by Ronald Jenkees Send your virology questions and comments to [email protected]

Transcript

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0:00.0	This week in virology, the podcast about viruses, the kind that make you sick.
0:10.4	From microbe TV, this is twiv this week in virology episode one thousand thirty five recorded on
0:18.0	August 11th, 2023. I'm Vincent Drakenello and you're listening to the podcast all about viruses
0:26.4	joining me today from Austin, Texas, Rich Condit. Hi there, Vincent. What have we got here? We got
0:34.0	another another cloudless day. I could use some clouds and it's about 102 out and it's been that way
0:43.2	for weeks and it's going to be that way for at least another couple of weeks. I think through
0:49.3	August, there had rained in weeks. 29 and sunny here in New York City also joining us from
0:56.3	Western Massachusetts, Alan Dove. Good to be here. It's 27 C 80 Fahrenheit, lovely, lovely day with
1:04.7	some puffy clouds coming through after a blast of thunderstorms blew through last night, which
1:11.4	seems to be like every few days we get another frontal system blasting through, but no damage here.
1:18.3	So all good. And from Madison, New Jersey, Brienne Barker. Hi, it's 83 Fahrenheit here,
1:26.1	28 Celsius. Nice sunny day. Not quite as humid as it has been, so I'll take it. You guys, amazing.
1:36.1	Yeah, Rich, it's like you live in a desert or something. Yeah.
1:39.7	Yeah. Well, it's Texas. It's hot. It's Texas. It's hot. Okay. We have one announcement just reminding
1:50.0	everyone. There is a second position available in Amy Rosenfeld's lab at the FDA. That is the
1:56.4	Food and Drug Administration. There's a part of it called Seiber Center for what?
2:04.4	Yeah. Biologics evaluation and research.
2:06.6	Oh, thank you. Biologics.
2:09.9	Biologics. And this is where research is also seed, seeder. Can you guess what that is?
2:15.8	Yeah, Center for Drug Evaluation and Research, right? There you go.
2:19.1	Yeah, that's across the way. Yeah. Right. Yeah. And I forget what the abbreviation is for the
2:24.8	devices branch, because I don't really know. Oh, there's a devices branch. Yeah, there's devices.
	...

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