The Truth About GLP-1 Nobody in Pharma Wants You to Know | EP 407
DR. GUNDRY PODCAST: GUT HEALTH, WEIGHT LOSS, AND NUTRITION
PodcastOne
4.6 • 1.8K Ratings
🗓️ 16 June 2026
⏱️ 20 minutes
🔗️ Recording | Apple Podcasts | RSS
🧾️ Download transcript
Summary
You can't scroll through your feed for five seconds without seeing someone talking about Ozempic, Wegovy, or the newest GLP-1 drug.
But here's what nobody is telling you: your body was already designed to make its own version of this appetite-suppressing hormone.
However, most of us have stopped feeding the good bacteria responsible for producing it.
In this episode, I'm breaking down the gut-centric theory of hunger, a fascinating concept that completely changed the way I think about appetite, cravings, and weight management.
Plus, I'll share what happened when I personally experimented with a specific category of food for my upcoming book and experienced something I can only describe as... injecting GLP-1. Without the injection.
On this episode, you’ll learn:
- The science behind what GLP-1 actually is (1:40)
- The real reason you feel like you can’t stop eating (and what you can do to stop it) (4:33)
- All about the jaw-dropping Chinese study where volunteers minimized their hunger (9:03)
- Exactly which foods crank up your body's natural GLP-1 production (11:29)
- The one food category I added to my own diet that had me leaving half my meal on the plate (13:43)
For the full episode transcript and show notes: https://drgundry.com/how-to-boost-glp1-naturally
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Transcript
Click on a timestamp to play from that location
| 0:00.0 | You can't turn on the TV or look at any social media without realizing that |
| 0:12.0 | GLP1 agonists are the rage. Whether it's Ozempic or Wagovi or Zepbon you name the drug or whether you're |
| 0:25.3 | doing full dose or micro dosing everybody's into gLP once. |
| 0:35.6 | A few years ago the wildfires came through my town in California, I lost my own. But what |
| 0:42.0 | haunted me wasn't the fire itself. It was what I saw in my clinic weeks later. Neighbors I'd |
| 0:48.2 | known for years, burning eyes, crushing fatigue, lungs loaded with invisible ash, they couldn't even see. That's when it hit me. |
| 0:56.8 | The air inside our homes is silently working against us. Every single day, not just during wildfires, |
| 1:03.8 | but right now, in your home, from your candles, your furniture, your cleaning products. |
| 1:10.5 | That's why I created total air as part of my new |
| 1:13.5 | brand Homekind. Medical grade filtration, the same standard I trusted in the operating room, |
| 1:20.7 | now protecting your family at home. Go to Homekind.com and use code clean air for 10% off total air filters. |
| 1:31.1 | Because every breath matters, make each one count. |
| 1:39.6 | First of all, we got to remember what GLP1 does and actually where it comes from. |
| 1:47.0 | So, GLP 1 is one of the mechanisms of producing satiety, feeling full. |
| 1:56.0 | And it's a hormone that's produced in our gut. |
| 2:00.0 | When it's made properly, believe it or not, by bacteria in our gut. |
| 2:05.9 | Now, there are other hormones that reduce hunger. Another one is colicestachycinicinin C CK. And that's produced |
| 2:15.3 | higher up in our gut with ingestion of fat. Now there are other |
| 2:21.2 | suppressing hormones. Many of you probably heard of leptin, which also tells us not to be hungry. |
| 2:29.2 | But interestingly enough, most overweight people have what's called leptin resistance. |
| 2:37.0 | Leptin resistance is very similar to insulin resistance. |
| 2:41.0 | You make lots of insulin, or you make lots of leptin, |
... |
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