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DR. GUNDRY PODCAST: GUT HEALTH, WEIGHT LOSS, AND NUTRITION

I Waited 25 Years to Make This Supplement. Here's Why. | EP 407.A

DR. GUNDRY PODCAST: GUT HEALTH, WEIGHT LOSS, AND NUTRITION

PodcastOne

Medicine, Alternative Health, Nutrition, Health & Fitness

4.61.8K Ratings

🗓️ 18 June 2026

⏱️ 22 minutes

🧾️ Download transcript

Summary

NAD is everywhere right now: supplements, injections, podcast topics, longevity clinics. And I'll be honest, when something gets this trendy, I get skeptical. But NAD is different. This is actually something I've been watching closely for nearly 25 years, and the science has finally caught up.

Here's what most people don't realize: the exhaustion, the brain fog, the slower recovery you've been chalking up to "just getting older"? That's often your NAD levels in freefall, and it's happening earlier than you think.

On this episode, I'm breaking down what NAD actually does inside your cells, why most supplements on the market are quietly failing you, and what I looked for when I finally designed my own formula — Gundry MD Elevate NAD+. I spent years waiting to make one until I could develop an NAD supplement that delivered you real results. 

On this episode, you’ll learn:  

  • What the "second baseman" is, and why it is the most important player in your cellular health (3:09)
  • All about the French Paradox and its connection to NAD research (4:32)
  • What fasting and strength training have in common that no one talks about (6:15)
  • The dirty secret about most NMN supplements on the market (7:35)
  • 3 reasons your NAD gets depleted (and what a well-designed formula like Gundry MD Elevate NAD+ actually does about it) (15:25)
  • The checklist I use to evaluate any NAD supplement (17:41)
  • What age should you actually start thinking about NAD support (12:21)
  • What real NAD support looks like in practice (hear my personal story) (10:57)


A special thank you for being part of our podcast family, use code PODCAST25 for 25% off your purchase of my brand-new NAD supplement. Code valid until 4/9/27 on all regular priced items. My Account and subscription price excluded. Can not be combined with other offers. Does not apply to bundles, devices and digital products.


For full show notes and transcript: https://drgundry.com/Gundry-MD-NAD-Supplement


Thank you to our sponsors! Check them out: 

  • Take your water to the next level with the AquaTru water purifier, go to aquatruwater.com and enter code “GUNDRY20” at checkout for 20% off.
  • Get $20 off your first box plus a free year of protein, like sirloin or ribeye at ButcherBox.com/GUNDRY.
  • Visit Juvent.com/GUNDRY and use code GUNDRY at checkout to get an extra $300 off your Juvent Micro-Impact Platform.
  • Get a quote today at Progressive.com.
  • Shop my new air filter, Homekind Total Air! Use code CLEANAIR for 10% off. 

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Transcript

Click on a timestamp to play from that location

0:00.0

NAD is everywhere right now. Supplements, podcasts, longevity clinics, everybody's talking about.

0:13.1

And I'll be honest, most of the time when something gets this trendy, I get a little skeptical.

0:18.8

But NAD is different. This is not a fat. This is something I've been

0:23.6

paying attention to for a long time. So what is NAD and why should you care?

0:34.6

A few years ago, the wildfires came through my town in California. I lost my own. But what

0:41.2

haunted me wasn't the fire itself. It was what I saw in my clinic weeks later. Neighbors I'd

0:47.3

known for years, burning eyes, crushing fatigue, lungs loaded with invisible ash, they couldn't

0:53.7

even see. That's when it hit me. The air inside

0:57.0

our homes is silently working against us. Every single day, not just during wildfires, but right

1:03.4

now, in your home, from your candles, your furniture, your cleaning products. That's why

1:10.2

I created total air as part of my new brand,

1:13.3

HomeKind. Medical grade filtration, the same standard I trusted in the operating room,

1:19.9

now protecting your family at home. Go to homekind.com and use code clean air for 10% off total air filters because every breath matters

1:32.4

make each one count. So first of all, NAD is involved in hundreds of chemical reactions. The fuel behind everything your cells do.

1:47.0

An NAD is really responsible for how your mitochondria make energy, ATP.

1:55.0

No NAD, you don't have any energy production. NAD not only activates your

2:04.5

Sertuans, your longevity genes, your body's guardians against aging and inflammation,

2:11.1

I could go on and on. But here's the problem. NAD declines steadily as you age.

2:18.3

Now here's why that decline matters more than most people realize.

2:23.3

The powerhouse of making energy.

2:27.3

In fact, I'll use an example that I use with my patients

2:32.3

to talk about how NAD is so important.

...

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