4.8 • 688 Ratings
🗓️ 11 November 2025
⏱️ 60 minutes
🧾️ Download transcript
In this episode, Dr. David Jockers joins Ben Azadi to break down what really happens inside your body during a 72-hour fast — from burning stored fat to reducing inflammation in the brain. Together, they explore how fasting resets dopamine, boosts mental clarity, and strengthens emotional resilience while tapping into your body's innate healing power.
You'll hear Dr. Jockers and Ben discuss how autophagy clears out old, damaged cells and replaces them with stronger, more stress-resilient ones. They also dive into how fasting triggers the creation of new mitochondria — your body's energy factories — helping you burn fat more efficiently and age more gracefully.
Finally, discover how fasting boosts growth hormone and resets your immune system, leading to greater energy, sharper focus, and improved longevity. Whether you're new to fasting or ready to take it to the next level, this episode reveals the science and strategy behind one of nature's most powerful healing tools.
In This Episode:
00:00 Introduction to Sacrifice and Dopamine
04:45 The Science of Fasting: 12 to 24 Hours
14:27 Autophagy and Metabolic Health
16:41 Air Quality and Autophagy Explained
28:29 Preparing for a Successful Fast
34:19 Understanding Cravings During Fasting
34:30 Timing Fasting with Menstrual Cycles
34:53 Managing Hunger and Ghrelin
36:03 Benefits of Extended Fasting
36:37 Fat Burning and Liver Health
38:41 Fasting and Intestinal Health
42:00 Dopamine Reset and Fasting
48:15 Supplements and Liquids During Fasting
54:59 Breaking the Fast and Refeeding
58:03 Gratitude and Final Thoughts
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"By tapping into body fat and producing ketones, your brain can function more clearly and reduce inflammation."
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| 0:00.0 | In most religious circles, it's the idea of sacrifice, right? And in a sense, overcoming our carnal desires. And I think in general, that's great. You and I know from a scientific perspective, that's going to give us a dopamine reset. You know what I mean? Dopamine is this amazing hormone that comes out, this neurotransmitter that comes out that gives us reward and pleasure. It's a beautiful thing. Like when we eat food, we release dopamine. |
| 0:21.3 | That's great. |
| 0:21.7 | We should enjoy our food. |
| 0:22.7 | Thank God we can. |
| 0:24.1 | But what happens is it's so easy to over-stimulate our dopamine. |
| 0:28.1 | Well, welcome back to the podcast. |
| 0:30.2 | Today's episode is on the shocking benefits of eating no food for 72 hours. |
| 0:35.6 | And this is actually a sit-down interview I had with my friend Ben Azadi for his |
| 0:40.2 | podcast, Metabolic Freedom. And we discussed exactly what's happening at different hour points, |
| 0:47.1 | different checkpoints along the way. If you do a fast, this is a fast where you can drink water, |
| 0:52.7 | but we're fasting from food for 72 hours. |
| 0:56.1 | And we break down all the details here, when you really start burning fat, when you start |
| 1:01.2 | producing ketones, when human growth hormone goes up, you're going to learn all of that |
| 1:05.6 | in great detail. And on top of that, we also answer a lot of the frequently asked questions |
| 1:10.4 | we get on fasting |
| 1:12.0 | and how to set yourself up for fasting, how to break the fast. |
| 1:16.2 | We go through all of that. |
| 1:16.9 | You guys are in for a treat on this episode. |
| 1:19.2 | Of course, you can check out Benazotti's podcast as well, the Metabolic Freedom Podcast. |
| 1:23.6 | He also has a great book called Metabolic Freedom that you can check out as well. |
| 1:28.8 | And you guys are going to enjoy this. Of course, if you need anything from natural health |
| 1:31.9 | perspective, check us out at Dr.jokers.com. The best research-based articles, infographics, |
... |
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