5 • 716 Ratings
🗓️ 17 November 2022
⏱️ 13 minutes
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0:00.0 | Hey all, welcome back to the Real Life Pharmacology podcast. I'm your host pharmacist, Derek Christensen. |
0:05.3 | Thank you so much for listening today. Go check out real life pharmacology.com. Get your free study |
0:12.6 | guide on the top 200 drugs. Great refresher if you're out of practice or if you're taking board |
0:20.0 | exams coming up, for example, or in |
0:22.1 | pharmacology classes, it's a no-brainer to have that 31-page PDF on the top 200 drugs. |
0:29.1 | So I put in my clinical experience, some of the most important things that come up, |
0:34.3 | as well as my experience in test-taking, with things that frequently come as well as my experience in test taking with things that frequently |
0:40.1 | come up there as well so go get that for free simply email we'll get you access to that no |
0:45.9 | cost to you at all all right the drug of the day today is citaglipton brand name of this medication |
0:54.0 | is genuvia and this medication is Genuvia. |
0:55.3 | And this medication is what's called a DPP4 inhibitor. |
1:01.6 | Now that DPP4 inhibitor name comes from its mechanism of action. |
1:08.5 | Citiglipton inhibits dipept peptidase 4. This prevents breakdown of incritin hormones. |
1:19.6 | And if you remember from physiology, so incritin hormones are important in glucagon, insulin, homeostasis, |
1:30.6 | and ultimately control of blood sugars. |
1:34.8 | So incritin hormones, a couple examples that you may be familiar with |
1:38.6 | if you've listened to previous podcasts. |
1:42.0 | GLP1 is an example of one of those hormones. So if you think about GLP1 agonist |
1:49.0 | medications, which we have covered previously, that's where that's come from. And Cidoglyptin |
1:56.9 | works on that pathway to basically increase that g-lp-1 hormone. |
2:05.6 | In addition, the other incritin hormone is GIP, and that would be glucose-dependent |
2:13.3 | dependent insulinotropic polypeptide. |
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