SIO369: Stress Increases Alzheimer's Risk in Women... But Not Men?
Serious Inquiries Only
Thomas Smith
4.6 • 1.1K Ratings
🗓️ 13 July 2023
⏱️ 37 minutes
🧾️ Download transcript
Summary
Today's guest is Hannah Edwards, a neuroscience grad student at Washington University in St. Louis, and part of the Cirrito Lab, which has released a new study on Alzheimer's and stress in mice. Stress causes the levels of Alzheimer's proteins to rise in females' brains but not males' brains. This difference may shed some light on the greater risk of developing Alzheimer's disease that women have. Hannah will take us through the study and also teach us a bit of the basics on Alzheimer's along the way!
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Transcript
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| 0:00.0 | Hello and welcome to Series Inquiries Only. This is episode 369. 12, 15, 18, that's magic |
| 0:23.0 | num, but no. 369, I'm Thomas Smith and today's episode is about Alzheimer's, |
| 0:28.5 | specifically some recent Alzheimer's research that may shed more light on why women tend to suffer |
| 0:35.7 | from Alzheimer's more than men. As you'll hear, some of that is women live longer, but controlling |
| 0:40.5 | for that there's still some amount that's not explained. And today's guest, Hannah Edwards, |
| 0:44.6 | is a grad student at Washington University and is part of the Cerrito Lab, which has recently released |
| 0:50.7 | a peer-reviewed study suggesting that stress could be the difference there. And along the way, |
| 0:55.9 | Hannah's going to explain some basics about Alzheimer's to us. And I know this is weird, |
| 1:00.4 | but I can't stop thinking of the movie The Father. If you didn't see that movie, it is about Alzheimer's |
| 1:05.3 | or at least I guess dementia. I'm not sure explicitly which, but oh man, that is a great movie. |
| 1:10.5 | Has nothing to do with the interview. I just can't, every time I talk about or think about this topic, |
| 1:15.3 | that's my first thought. Such a great performance, such a brilliantly written movie. So that's my |
| 1:19.7 | recommendation to go with this. Again, nothing to do with Hannah or this episode in any way. I just hope |
| 1:26.9 | that people saw that because it was really, really good. All right, let's see. Some other total BS |
| 1:33.2 | before getting to the interview with Hannah. So it does look like the idea of doing what people |
| 1:38.9 | have dubbed online seriously awful movies. I don't know if I love that seriously awful movies, |
| 1:44.7 | because it doesn't really play on anything. I mean, kind of serious inquiries only, |
| 1:50.5 | seriously awful. But the seriously awful is only like, it's like eight steps removed from |
| 1:55.9 | the original source of the word play. I don't know, maybe I'm exaggerating. It's a couple steps |
| 2:00.9 | removed from that part of the word play. So to me, it didn't strike me as the obvious name that |
| 2:06.2 | some other people thought was really good, but maybe I'm wrong. Maybe it is a good one for now. |
| 2:10.4 | I mean, I don't have a better one. So fine. Yeah, seriously awful movies. Anyway, that does seem |
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