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Open to Debate

Should We Use Gene Editing to Make Better Babies?

Open to Debate

Open to Debate

Society & Culture, Education, News

4.62.2K Ratings

🗓️ 23 April 2026

⏱️ 52 minutes

🧾️ Download transcript

Summary

Your doctor tells you that, should you wish to have a child, that child is likely also to carry the disease. But a new gene-editing technology could ensure that your baby is -- and remains -- healthy. Should you do it? Critics say the technology will exacerbate inequality and meddle in the most basic aspect of our humanity. Now, we debate: Should We Use Gene Editing to Make Better Babies? This ethical conundrum is at the crux of this week's debate, originally broadcast in February 2022. Arguing Yes: Dr. George Church, Geneticist & Founder, Personal Genome Project; Professor, Genetics, Wyss Institute and Harvard Medical School Amy Webb, Chief Executive Officer, Future Today Strategy Group; Professor, NYU Stern School of Business  Arguing No: Marcy Darnovsky, Executive Director, Emerita, Center for Genetics and Society  Françoise Baylis, Distinguished Research Professor, Emerita, Dalhousie University; President, Royal Society of Canada  Emmy award-winning journalist John Donvan moderates  Join the conversation on Substack - share your perspective on this episode and subscribe to our weekly newsletter for curated insights from our debaters, moderators, and staff.  Follow us on YouTube, Instagram, LinkedIn, X, Facebook, and TikTok to stay connected with our mission and ongoing debates.  Learn more about your ad choices. Visit podcastchoices.com/adchoices

Transcript

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0:00.0

This is open to debate. I'm John Donvan. Hi, everybody. Something astounding happened just a few months ago.

0:12.8

Doctors at a hospital in Philadelphia were able to successfully treat a seven-month-old baby who had a rare liver disease,

0:20.1

and it was done using CRISPR.

0:22.6

That is the technology that let scientists edit DNA.

0:26.6

This baby, according to the study that discusses the case, now has improved liver function,

0:32.4

can eat protein, and has reduced medications.

0:36.1

Now, a lot of people have been asking, what if we don't have to wait until birth to treat these serious illnesses or prescribe medicine?

0:42.4

What if we could go directly to the source, our DNA in human embryos,

0:47.4

to prevent these diseases before they even get started?

0:51.0

With the right amount of oversight, Could this lead to genetically advantaged children

0:55.5

that will help future generations? Well, some people think that creating designer babies,

1:00.7

so to speak, is science going too far? Some of what's able to be done at all is limited,

1:07.7

that it may create competition for the perfect baby, and even asking should this

1:13.0

godlike power be in human hands at all. So the question, should we use gene editing to make

1:18.8

better babies? We did this debate a few years ago when the pandemic was still in full swing,

1:23.8

and it is still a really interesting conversation. So let's get to it. Picture this.

1:30.2

A genetic disease runs in your family. Your doctor warns you that if you try to have a child,

1:35.6

that child is likely to inherit the disease, but new gene editing technology could change your

1:41.5

child's fate. Critics say this technology will exacerbate inequality,

1:46.0

pressure everyone into editing their children to stay competitive, and will meddle with the most basic aspect of our humanity, our DNA.

1:55.0

Others say with safeguards against abuse, this technology could benefit us in a host of ways. In that context, we debate

2:02.9

this question. Should we use gene editing to make better babies? That is the debate we're launching

...

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