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Science Weekly

Secrets of ageing: what makes me age?

Science Weekly

The Guardian

Science

4.21K Ratings

🗓️ 30 July 2024

⏱️ 21 minutes

🧾️ Download transcript

Summary

Humans have always been obsessed with getting old, or rather staying young, but now science is beginning to catch up. Longevity has become a hot topic, from university laboratories to Silicon Valley startups. In the first of a Science Weekly three-part miniseries on ageing, Ian Sample speaks to Richard Faragher, a professor of biogerontology at the University of Brighton, to discover what we know about the biological hallmarks of ageing in our bodies –and why we have evolved to have the lifespans we do. Help support our independent journalism at theguardian.com/sciencepod

Transcript

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0:00.0

This is the Guardian. Humans are obsessed with getting old or more precisely staying young.

0:17.0

And while there have always been those willing to halt anti-aging elixes and

0:22.4

sell us dreams of long healthy lives, so far the quest

0:26.2

for eternal youth has been a dead end.

0:29.7

But now science is beginning to catch up. This is an exceptionally hopeful time. This is the

0:36.3

first time in human history where we have a pretty good idea what some of the mechanisms driving aging and the diseases that accompany it.

0:50.0

As you can imagine, this has turbocharged our fascination with longevity.

0:55.0

Aging is 80% to 90% the cause of heart disease, Alzheimer's.

0:59.0

If we didn't get old and our bodies stayed youthful, we would not get those diseases.

1:03.6

We have discovered several genes in our centenarians.

1:08.0

We can imitate them.

1:09.5

If we can understand what happens to them,

1:11.5

we can create it as a drug. I've looked at my blood

1:14.8

by chemistry and I'm actually now younger and healthier than I've ever been.

1:19.6

And even though they say one thing money can't buy is time, that's not going to stop Silicon Valley billionaires.

1:27.0

The only objective we have is don't die.

1:30.0

Don't die. It's that simple.

1:35.0

Most of us aren't going to get infusions of young blood or take hundreds of supplements a day.

1:41.0

But beneath the hype there is something troubling happening.

1:46.3

The global population is aging. By 2030, one in six people in the world will be age 60 years or over. Today a child born in the UK

1:56.8

has more than 50% chance of living into their 90s. That doesn't mean they'll be healthy

2:01.9

when they get there of course.

...

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