5 • 716 Ratings
🗓️ 22 August 2019
⏱️ 14 minutes
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0:00.0 | Hey all, Eric Christensen here, pharmacist with the real-life pharmacology podcast. |
0:05.8 | I'm back at you today with another episode. |
0:09.4 | And I'm going to cover Ocel tamavir, which is a medication that is indicated in the treatment and prophylaxis of influenza. |
0:20.3 | It's really at this point our go-to in clinical practice. |
0:25.1 | Obviously, that can change over time, |
0:27.2 | so certainly take a peek at guidelines |
0:29.6 | and be sure to look out for any changes in the future. |
0:33.8 | But the brand name here is Tamiflu. |
0:37.0 | And the way this drug works is it inhibits the viral enzyme neuraminidase. |
0:44.3 | Now this enzyme is necessary for the virus to basically be able to release more virus, proliferate, and obviously go on and continue to infect other cells |
1:00.4 | throughout the body. With influenza, you know, common classic symptoms, fever, body aches, |
1:09.2 | upper respiratory symptoms, those are really, upper respiratory symptoms. |
1:11.6 | Those are really the hallmark symptoms |
1:14.8 | as far as an influenza infection there. |
1:19.0 | Now with treatment and prophylaxis, |
1:22.7 | you've got to remember that there are different doses. |
1:26.4 | And specifically talking about adults, usual dosing is 75 milligrams once a day and that's |
1:35.3 | usually going to be your prophylactic dose for a normal healthy adult for a treatment, excuse me me 75 milligrams twice a day and prophylaxis is generally going to be for a |
1:50.8 | longer period of time treatment of influenza is generally only going to be for five days and if you |
1:58.5 | think about that that really makes. The usual course of influenza |
2:02.2 | is probably in that five to seven day period. You know, I can speak from personal experience. |
2:09.0 | I had influenza several years ago now. And first off, it's not very much fun. The fever and the body aches were definitely intense |
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