New Era for Osteoporosis Treatment: CTX, P1NP & Beyond
The Root Cause Medicine Podcast
Kate Kresge
4.8 • 581 Ratings
🗓️ 16 October 2025
⏱️ 74 minutes
🔗️ Recording | iTunes | RSS
🧾️ Download transcript
Summary
James Greenblatt explores the evolving science of low-dose lithium as a neuroprotective intervention — highlighting its potential to prevent, slow, and even reverse cognitive decline associated with Alzheimer’s disease. He emphasizes that safe, nutritional lithium (2-10 mg) can support brain health by reducing neuroinflammation, promoting neuroregeneration, and stabilizing mood—without the risks associated with pharmaceutical doses. Clinicians are encouraged to assess lithium status through hair mineral analysis, monitor thyroid and kidney function, and consider environmental and dietary influences on endogenous lithium levels. By integrating low-dose lithium into a comprehensive, individualized care plan—including lifestyle modifications and targeted testing—practitioners can leverage this simple mineral to support mental clarity, impulsivity regulation, and long-term cognitive resilience.
Transcript
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| 0:00.0 | Well, hello there and welcome to the root cause medicine podcast. I'm Dr. Kate Kreske, |
| 0:03.7 | your host for today. And we're diving into osteoporosis and bone health. Now, in 2025, |
| 0:08.8 | bone health is so much more than just minerals, vitamin D, and vitamin K. It includes advances in |
| 0:14.4 | things like blood testing for markers of bone turnover, how new technology can give us even |
| 0:19.8 | deeper insights to a Dexas scan than we thought |
| 0:22.2 | were possible. |
| 0:23.3 | And specific recommendations around protein, vibration, exercise, and more that you may not |
| 0:28.7 | have heard. |
| 0:29.5 | Joining us today is Margie Bissinger. |
| 0:31.8 | She's a physical therapist and she has over 30 years of experience teaching practitioners |
| 0:35.5 | about nutrition, bone health, and helping clients |
| 0:38.1 | to build healthy bones and reduce the risk of fractures. This is a fascinating conversation today. |
| 0:43.4 | If you know Margie, you know that she has a really successful podcast where she educates |
| 0:47.0 | people about bone health and osteoporosis all the time. And she just got back from this year's |
| 0:51.6 | international conference on osteoporosis. Let's dive in. |
| 0:55.0 | So you're going to notice the theme over the next few weeks on the podcast and that's what we're really diving into metabolic health. |
| 1:00.0 | And the reason we're doing that is because we're building momentum to something called FulScript Forward on October 17. |
| 1:05.0 | FullScript Forward is a day long event, a couple hours where we're featuring incredible experts who are discussing things like metabolic flexibility, inflammation, pharyoptosis in longevity. |
| 1:16.3 | We know that your clients are inundated with information about what longevity is, and we want |
| 1:20.9 | to empower you with the tools and information you need to stay on the leading edge and to guide |
| 1:24.8 | them to what to do based on science and the evidence. So you can head to Folescriptforward.com to sign up and get registered. I will be there along with the rest of our amazing team. We can't wait to see you. Margie Vissinger, welcome to the Rupcast Medicine podcast. Oh, I'm just so happy to be here. Thank you so much for inviting me. I'm thrilled to have you here. |
| 1:44.7 | You are beloved by our team at Volscript and frequently cited as the leading expert we have on |
... |
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