Breakthrough Evidence for Lithium in Alzheimer’s and Mental Health Treatment

The Root Cause Medicine Podcast

Kate Kresge

Alternative Health, Medicine, 810564, Health & Fitness

4.8 • 581 Ratings

🗓️ 30 October 2025

⏱️ 56 minutes

🔗️ Recording | iTunes | RSS

🧾️ Download transcript

Summary

James Greenblatt explores the evolving science of low-dose lithium as a neuroprotective intervention — highlighting its potential to prevent, slow, and even reverse cognitive decline associated with Alzheimer’s disease. He emphasizes that safe, nutritional lithium (2-10 mg) can support brain health by reducing neuroinflammation, promoting neuroregeneration, and stabilizing mood—without the risks associated with pharmaceutical doses. Clinicians are encouraged to assess lithium status through hair mineral analysis, monitor thyroid and kidney function, and consider environmental and dietary influences on endogenous lithium levels. By integrating low-dose lithium into a comprehensive, individualized care plan—including lifestyle modifications and targeted testing—practitioners can leverage this simple mineral to support mental clarity, impulsivity regulation, and long-term cognitive resilience.

Transcript

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0:00.0	Well, hello and welcome to the root cause medicine podcast. I'm your host for today, Dr. Kate Kresge,
0:05.0	and today we're exploring one of the most exciting frontiers in brain health research. Lithium,
0:09.7	yes, the very same mineral used for decades in psychiatry might hold a key to preventing or even
0:15.2	reversing Alzheimer's disease. A brand new paper out of Harvard just showed that lithium naturally
0:20.6	exists in the brain and that it gets depleted early in Alzheimer's, likely because it binds to amyloid plaques.
0:27.2	Even more fascinating, researchers have found that a special form of lithium, called lithium or a teat, can sneak past those plaques and restore normal brain levels in animal models, actually reversing memory loss.
0:39.8	To help us make sense of all this, I'm joined by Dr. James Greenblatt,
0:43.5	Integrative psychiatrist, researcher, and one of the world's foremost experts on nutritional psychiatry and trace minerals.
0:49.2	Dr. Greenblatt has been talking about lithium orate and it's used in mental health and cognitive decline for decades long before it became trendy.
0:57.2	Today we'll dive into what lithium actually does in the brain.
1:00.4	Why it may be protective against Alzheimer's and other nerve degenerative conditions, and
1:04.7	how clinicians can safely consider its use.
1:07.6	Before we get started though, I've got a special question for the practitioners in the
1:10.5	audience. What if your supplement dispensing, I've got a special question for the practitioners in the audience.
1:11.5	What if your supplement dispensing, patient education, and treatment planning all lived in one
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1:27.8	Well, we full script. the comprehensive care delivery platform designed to reduce administrative
1:32.5	burden and enhance clinical impact. From automated refills and lab ordering with interpretation,
1:37.6	to evidence-based protocols and built-in adherence support. FullScript integrates the tools you need
1:43.3	to streamline care and stay focused on what matters most,
1:46.6	your patients.
	...

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