Welcome back to the channel. On this channel, we talk about clinical studies. We talk about evidence-based

medicine. We talk about health policy. That's my wheelhouse. And that's what you get on this channel. We've taken deep dives into many cancer clinical trials. Today, we're going to talk about some lies and exaggeration. I've had a number of professors email me and DM me to point out that there are people in our profession who are exaggerating what we know about kids vaccines

and they are pretty worried about that because the last thing you want to do as a scientist is to

exaggerate what you know about something and so i'm going to walk you through it this is lies in

exaggeration i think reasonable people can disagree about the threshold for regulatory authorization or approval for different products.

Reasonable people can disagree.

We can all say adiucanamab, it was way too low.

We can all say some cancer drugs, it's way too low.

Some of us may argue that boosters, a third dose, or the fourth dose, and people over their age of 50, is too low.

And some people might say the regulatory hurdles that this FDA used for emergency use authorization

in young kids is too low.

They would have liked to see, and I'm included in this, randomized control trials,

powered for clinical endpoints, severe disease, hospitalization, MISC.

That would be hundreds

of thousands of kids, maybe millions of kids, but that's okay. Jonas Salk did hundreds of thousands

of person randomized trial for the polio vaccine and Pfizer can afford it. We know that to be

true. There may be other people who feel like I do. Those people may include Marion Gruber and

Phil Krause. Those were the two FD officials who resigned in vaccine drug products.

But putting that aside, reasonable people disagree on the threshold for approval. Put that aside. Let's say something has been authorized. Something has been approved. Well, then what you want is public help to be as brutally honest as possible. What do you know about this product? What don't you know? Tell me what you know. Be honest about it. And tell me what you don't know. But if they start to exaggerate or to say things that we don't know to be true, that could lead to a situation where some of what they're saying turns out not to be true. It just could be bluff and bluster. And if that's the case, it could lead to horrific

losses and trust. It also subverts the autonomy of the person listening. I mean, we all make

autonomous health care choices contingent on knowing the facts. And if we don't know all the facts

or we are exaggerated the facts, that's not a free choice. So let me talk about lies and exaggeration.

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