meta_pixel
Tapesearch Logo
Log in
Plenary Session

Enact Trial - Enza vs Active Surveillance in Localized Prostate Cancer

Plenary Session

Vinay Prasad, MD MPH

Policy, Medicine, Health, Oncology, Science & Medicine

4.8798 Ratings

🗓️ 20 June 2022

⏱️ 15 minutes

🧾️ Download transcript

Summary

What happens when you treat people with $168,000 a year medicine when most of them will never need treatment, and all of them don't need treatment now

Transcript

Click on a timestamp to play from that location

0:00.0

Welcome back to the channel.

0:01.9

This is Plenary Session, a podcast at the intersection of medicine, oncology, and health policy.

0:07.4

You're watching the video feed and some of you are listening to the audio feed.

0:10.4

If you're on the audio feed, this time I've got slides, you're going to want to hop over.

0:13.6

And what we're talking about today is the enact trial.

0:16.8

A lot of people have asked for my opinion about the enact trial.

0:20.0

I think they know what they're going to get.

0:22.1

And this is, of course, a new study out now in JAM Oncology, active surveillance plus

0:27.0

enzaludamide monotherapy versus active surveillance alone in patients with low risk or intermediate

0:31.7

risk, localized prostate cancer, the enact study, a phase two study of enzymide. That's right, the extremely costly, something in the ballpark of $130,000 to $180,000 of year medication, enzaludamide, the androgen receptor antagonist in localized prostate cancer, where your control arm is a healthy dose of active surveillance, because that's what you'd otherwise do in this

0:55.3

setting and this is quite the study quite the study the first thing i always say when i read these

1:00.9

studies is this and i'm then i keep saying it somebody said you know you've laid off it recently i was

1:06.5

like well let me get right back on it uh We want to thank the patients and investigators who participated.

1:12.5

That's sweet.

1:13.2

That's nice.

1:13.9

I can get behind that.

1:15.2

And then medical writing assistance was provided by blah, blah, blah, blah.

1:18.3

And editorial support was provided by blah, blah, blah, blah, from blah, blah, blah, which

1:21.8

is funded by the study sponsors.

1:24.0

Medical writers.

1:25.2

Medical writers.

1:26.3

Do you, what would you say if kids in middle school and high school got medical writers to do their homework for them?

...

Please login to see the full transcript.

Disclaimer: The podcast and artwork embedded on this page are from Vinay Prasad, MD MPH, and are the property of its owner and not affiliated with or endorsed by Tapesearch.

Generated transcripts are the property of Vinay Prasad, MD MPH and are distributed freely under the Fair Use doctrine. Transcripts generated by Tapesearch are not guaranteed to be accurate.

Copyright © Tapesearch 2026.