Is There a Link Between Genetic Mutations and Eating Disorders? Scientist-Physician Dr. Michael Lutter Shares His Fascinating Research

Optimal Protein Podcast with Vanessa Spina

Vanessa Spina

Nutrition, Fitness, Health & Fitness

4.6 • 795 Ratings

🗓️ 4 December 2023

⏱️ 65 minutes

🔗️ Recording | iTunes | RSS

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Summary

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This episode is about some incredibly fascinating research - the work of scientist physician Dr. Michael Lutter who has made numerous fascinating discoveries, including identifying the first two rare genetic mutations associated with Anorexia Nervosa. He also discovered a link with binge eating and GLP-1 expression. Dr. Lutter has a passion for using translational neuroscience approaches to improve the treatment of patients with depression, anxiety, and eating disorders. See below for full bio.

Dr. Michael Lutter's book, Gifted

Dr. Michael Lutter's website

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Dr. Lutter completed combined MD and PhD training in the prestigious Medical Scientist Training Program at the University of Texas Southwestern Medical Center in 2003. After finishing medical school, Dr. Lutter entered the research-track of the Psychiatry Residency Program at UT Southwestern, There, he discovered that the appetite-stimulating hormone ghrelin affects mood and appetite in response to stressful situations. He joined the Psychiatry Department as a faculty member in 2008 and continued his research on mood and feeding with a special focus on Eating Disorders. In 2012 he was recruited to the Psychiatry Department of the University of Iowa where he identified the first two rare genetic mutations associated with Anorexia Nervosa. In 2016 he joined the Eating Recovery Center and while working as a Physician-Scientist in their newly opened Inpatient Hospital studied novel treatments for patients dealing with depression and binge-eating.

He has published 28 original research papers, written 7 review articles, and contributed 3 book chapters. In addition, he has regularly presented at national and international meetings including the Society for Neuroscience, the American College of Neuropsychopharmacology, and the International Conference on Eating Disorders. He continues to pursue his passion of using translational neuroscience approaches to improve the treatment of patients with depression, anxiety, and eating disorders.

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Transcript

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0:00.0	Welcome to the Optimal Protein Podcast. I'm Vanessa Spina.
0:04.7	Hello, my friends. Welcome back to the podcast. I'm your host, Vanessa, and I am super excited for today's episode.
0:13.3	This was one of the most mind-blowing podcast interviews that I've had the privilege of getting to do with Dr. Michael Luter.
0:23.2	He has made some really incredible discoveries.
0:27.4	And discoveries, I think, that are going to impact thousands and thousands of people around
0:32.0	the world who have been dealing with eating disorders or have dealt with eating disorders or
0:37.7	disorder eating at any stage of their life he actually discovered that there is a genetic
0:44.3	mutation that is responsible for a lot of eating disorders most of them and that it has
0:52.8	to do with the body's inability to either break down fat through beta
0:57.1	oxidation or not make glp1 which is our satiety one of our major satiety hormones or not able
1:05.8	to metabolize the breakdown products of beta oxidation or burning fat for fuel. And even in some cases,
1:14.9	inhibiting the mTOR pathway and the effects on the mitochondria, his work and research is
1:20.2	absolutely fascinating, completely blew my mind. And I am so honored to have him on the podcast
1:27.3	with us today talking about his discoveries as a scientist physician.
1:32.2	It is so amazing to get to talk to someone who is actively incorporating the discoveries that they are making in the lab real time with patients.
1:41.7	So I know you're going to get a ton from this episode and can't wait to
1:45.7	hear your takeaways and insights. Now before we fully jump into today's episode, I want to take
1:51.4	a really quick moment to tell you about a company that is doing something absolutely
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2:03.5	many of us are deficient in and not even aware of it. And that nutrient is light and specifically
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2:16.6	red light therapy's ability to support our
	...

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