Hey, all, welcome back to the Real Life Pharmacology podcast. I'm your host,

pharmacist, Eric Christensen. Thank you so much for listening today. Go check out RealLife Pharmacology.com.

Grab your free 31 page PDF on the top 200 drugs. It's a great study guide, great refresher.

No-brainer definitely to have to your medication-related library.

So simply an email, we'll get you access to that. We'll also get you updates when we've got

new podcast episodes available and other content as well. So go do that at real-life pharmacology.com. All right, let's get into the drug of the day today,

and that is insulin Lyspro. Brand name of this medication is Humelog, and I will say that with a caveat,

that there is a new formulation of LISP Pro out called Lyom Jev as well.

I'm not going to cover that specifically here on this podcast episode.

It is on my to-do list to tackle that one in the coming weeks.

But I definitely wanted to stick mostly to Humilog here because there's definitely quite a bit of information surrounding insulin

and the use of rapid-acting insulin in general.

So first and foremost, mechanistically,

we obviously want to know and think why and how insulin works.

So insulin plays a huge role in regulatory processes pertaining to energy and metabolism of carbohydrates, proteins, and fats.

Okay. And so a few of the things that it does, and I'm going to primarily focus on the stuff that

matters most to us regarding management of diabetes and blood sugar.

So first and foremost, it stimulates glycogen synthesis.

And if you remember from maybe biology, glycogen is essentially a storage form of glucose.

So insulin stimulates that storage of glucose.

Another thing it can do is it can increase ion permeability across cell membranes.

So particularly in the bloodstream, it'll pull out various electrolytes. So potassium is probably the

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