Hey all, welcome back to the Real Life Pharmacology podcast. I'm your host,

pharmacist Sarah Christensen. Thank you so much for listening today. As always, go check out

real life pharmacology.com and get a hold of your free Top 200 study guide. I would get the

top 200 meds. I lay out my most important clinical practice pearls as well as things that show up on exams frequently.

So I go take advantage of that. Simply an email. We'll get you access to that.

All right. Well, let's get into the drug of the day today, and that is a tannercept.

Brand name of this medication historically is Enbro.

And this medication is classified as a demard.

So that's a disease-modifying anti-rumatic drug.

So as you could imagine, this medication is probably going to be used for rheumatic-type diseases.

So in my practice, the situation I see this medication used most for is rheumatoid arthritis,

followed potentially by psoriasis and psoriotic arthritis.

It can also be used for ankylosing spondylitis and a few other obscure ones as well, which I won't

mention, but it can be used for a few different immunologic type diseases.

So with that, how does this medication work?

So Eitanercept is essentially a protein that's been developed, and it's considered a biologic medication,

and it has what's called a TNF receptor linked to an IgG molecule.

So what that does is that TNF receptor basically binds up the molecule TNF,

which is tumor necrosis factor.

Now in the body physiologically, TNF plays a huge role in the inflammatory process, which

that makes sense because we're trying to reduce inflammation in something like

rheumatoid arthritis, for example.

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