Hey all, welcome back to the Real Life Pharmacology podcast.

I'm your host, pharmacist Eric Christensen.

Thank you so much for listening today.

Go check out real life pharmacology.com.

I've got a free PDF on the top 200 drugs.

Great study guide, great refresher, whether you're in practice or a student.

I put together on the top 200 drugs, some of my most important clinical pearls that will come up in practice,

as well as a lot of things that are going to show up on board exams throughout your career.

So go check that out.

Simply an email will get you access to that

nice resource for free. So go take advantage of that for sure. The drug of the day today is

endapamide. Brand name of this medication is Lozol. At least that's the brand name I have heard used

most often.

It is an older drug, so it's been a long, long time since I've heard the brand name Lozol uttered from anybody.

This is a thiozide-like diuretic.

So you can put it in the same category mechanism of action, adverse effects, or at least pretty similar,

to chlorthalidone and hydrochlorothiozide.

Mechanistically, being a thiaside or thyside like diuretic,

ultimately it causes sodium, chloride, and water excretion.

And the area of the nephron that that happens is the proximal segment of the distal tubule.

So that's where this drug works is in the nephron.

And with that sodium, chloride, water excretion, potassium will also go with it,

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