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Dr. Jockers Functional Nutrition

Improving the Mitochondrial-Microbiome Connection for Optimal Health with Jason Prall

Dr. Jockers Functional Nutrition

Dr. Jockers

Health & Fitness, Nutrition, Alternative Health

4.8688 Ratings

🗓️ 23 December 2025

⏱️ 54 minutes

🧾️ Download transcript

Summary

In this episode, Dr. Jockers explores with Jason Prall how mitochondrial health and the gut microbiome are deeply connected, shaping energy, inflammation, and long-term resilience. You'll learn why mitochondria are far more than energy producers and how their communication drives whole-body health.

 

In this episode, you'll discover how the microbiome helps translate food into signals that influence mitochondrial function, metabolism, and cellular repair. Jason breaks down why diversity in the gut matters and how everyday choices quietly shape this internal dialogue.

 

In this episode, you'll hear practical insights on how sleep, light exposure, movement, fasting, and stress act as signals that either strengthen or weaken this mitochondrial–microbiome connection. The conversation leaves space to rethink how small lifestyle shifts can create powerful biological change.

 

 

In This Episode: 

00:00 Introduction to Human and Mitochondrial DNA

04:06 Deep Dive into Mitochondria and Aging

14:01 Understanding the Gut Microbiome

25:38 Environmental Factors Affecting Health

29:19 Mindfulness and Detoxification

29:55 Impact of Thoughts on Health

31:06 Personalized Health Approaches

31:39 Universal Health Strategies

33:43 Importance of Sleep

37:19 Exercise and Movement

41:07 Fasting and Meal Timing

45:48 Stress and Recovery Balance

48:42 Final Thoughts and Resources

 

 

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"Every disease involves mitochondria—when mitochondrial function fails, the body breaks down." 

 

 

Subscribe to the podcast on:

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Resources:

 

Connect with Jason Prall:

 

Connect with Dr. Jockers:

If you are interested in being a guest on the show, we would love to hear from you! Please contact us here! - https://drjockers.com/join-us-dr-jockers-functional-nutrition-podcast/ 

Transcript

Click on a timestamp to play from that location

0:00.0

So we have, of course, our human DNA, right?

0:02.6

And it's the double helix.

0:04.1

Well, mitochondria have a circular DNA, right?

0:06.3

And we get this DNA from our mothers, right?

0:08.9

So the health of our mothers specifically, right?

0:11.0

All of us get our mitochondria from our mothers.

0:13.6

The health of our mother's mitochondria actually is pretty critical to our health throughout

0:19.0

life.

0:20.2

Well, welcome back to the podcast.

0:22.8

I've got a repeat guest, Jason Prawl.

0:26.2

And we're talking all about how the gut microbiome communicates with our mitochondria and how things

0:33.6

like food and food timing, sleep, light and light timing, how all of that impacts

0:40.1

the communication process between the gut microbiome and the mitochondria and how that plays

0:46.2

a role in our energy levels, our sleep quality, our levels of inflammation, our immune

0:51.9

response. This is a really, really powerful information.

0:55.2

You guys are going to really enjoy it. And if you want more from Jason, we've got episode 370.

1:00.7

We talked about healthy aging, sleep, light, and circadian rhythm. And then also episode 2.92,

1:05.9

we talked about his book, Beyond Longevity, He'll Faster, Feel Better, and Thrive. Also, that's a great book, guys. You can get it on

1:13.4

Amazon.com or in the show notes. Jason has a fantastic book. One of the best books I've read on

1:18.5

longevity. Again, it's called Beyond Longevity. He'll faster, feel better, and thrive at any age.

1:24.1

You guys are going to really enjoy this interview. And if you're enjoying this podcast,

1:28.4

please leave us a five-star review. Those reviews help us reach more people and impact more lives

...

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