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Feel Better, Live More with Dr Rangan Chatterjee

How To Live Longer and Better: The Secret to Super Ageing with Dr Eric Topol #626

Feel Better, Live More with Dr Rangan Chatterjee

Dr Rangan Chatterjee

Alternative Health, Medicine, Health & Fitness, Mental Health

4.711.7K Ratings

🗓️ 18 February 2026

⏱️ 97 minutes

🧾️ Download transcript

Summary

What if the secret to living well into your 80s and 90s is nothing to do with your DNA? What if the longevity hackers have got it wrong, and it’s actually far more simple than you think to become a ‘super ager’? We all want to live a long, happy and healthy life. But with the vast majority of US and UK people over 60 having at least one chronic disease, the odds are currently stacked against us. Or are they? In this enlightening episode, you’ll learn why healthspan matters more than lifespan – and why it’s never too late, or too early, to take action. My guest is Dr Eric Topol, a practising cardiologist, Professor of Molecular Medicine, and one of the top 10 most cited researchers in medicine. Eric has spent his career at the forefront of genomics and artificial intelligence. Yet in his new book Super Agers: An Evidence-Based Approach To Longevity, he sets out a surprisingly low-tech solution to ageing well. And it’s one that has nothing to do with your parents’ health. In this episode, Eric talks me through what his Wellderly Project – research on remarkably healthy people in their late 80s – revealed about the health metrics that matter. He explains his ‘lifestyle plus’ approach to health, which includes not just the basics like nutrition, exercise and sleep, but evidence-based influences such as environmental toxins, emotional outlook and social connections. His message is an empowering one: making the right choices today could add seven to 10 healthy years to your life, regardless of your family history. We tackle some thought-provoking topics, such as the idea that cancer screening isn’t working, and that forever chemicals and microplastics are far more dangerous than we’ve been led to believe. We discuss the personalisation of healthcare – how knowledge of your own data is the most effective way to drive behaviour change. And Eric shares his positive insights on how AI will be able to help us predict – and take control of – our future health. The ‘big three’ chronic diseases, cancer, heart disease and neurodegeneration, start developing 20 years before we see symptoms. So that’s a big window of time in which you can make a difference to your risk – and a truly empowering message you can start acting on today. Support the podcast and enjoy Ad-Free episodes. Try FREE for 7 days on Apple Podcasts https://apple.co/feelbetterlivemore. For other podcast platforms go to https://fblm.supercast.com.   Thanks to our sponsors: https://boncharge.com/livemore https://onepeloton.co.uk   Show notes https://drchatterjee.com/626   DISCLAIMER: The content in the podcast and on this webpage is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your doctor or qualified healthcare provider. Never disregard professional medical advice or delay in seeking it because of something you have heard on the podcast or on my website.

Transcript

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0:00.0

Let's accept that we're aging, right?

0:03.0

It's a biologic process.

0:05.0

But let's not accept that we can't make a huge dent in age-related diseases.

0:11.0

With AI, multimodal AI and all these new layers of data,

0:15.0

we're going to go into an era of prevention that I am really excited about.

0:20.0

Treatment is not the end all. It's prevention.

0:23.8

Hey guys, how you doing? I hope you having a good wheat so far. My name is Dr. Rongan Chatterjee,

0:30.2

and this is my podcast. Feel Better, Live More.

0:36.5

95% of Americans over the age of 60 are living with at least one chronic disease, almost as many

0:45.0

have two, and the picture is similar in the UK. Is this really what we want our later years

0:52.0

to look like? You see, there's so much talk about longevity

0:55.8

these days, and I don't know about you, but I sometimes really question the value in living

1:01.3

longer if it means living with poor health and being a burden to our loved ones. But today's

1:08.6

conversation presents an appealing, achievable alternative. My guess makes

1:14.3

the case that focusing on health span rather than lifespan by making some very achievable lifestyle

1:21.8

changes can give each of us an extra seven to 10 years of disease-free living.

1:28.3

Dr. Eric Topol is a cardiologist and one of the world's most cited scientific researchers

1:35.3

who has spent years at the cutting edge of genomics and the use of artificial intelligence in medicine.

1:42.3

And yet his findings consistently point back to a wonderfully empowering solution, the basics.

1:50.0

In his new book, Super Ages, an evidence-based approach to longevity,

1:56.0

Eric explains that the big three diseases that reduce health span,

2:00.0

cancer, heart disease, and neurodegeneration,

...

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