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The Human Upgrade: Biohacking for Longevity & Performance

How To Clear Brain Fog (Simple Methods) : 1332

The Human Upgrade: Biohacking for Longevity & Performance

Dave Asprey

Fat, Health & Fitness, Meditation, Biohacking, Lifestyle, Diet, Science, Self-improvement, Fasting, Nutrition, Hacking, Fitness, Brain, Wellness, Education

4.67.3K Ratings

🗓️ 21 September 2025

⏱️ 12 minutes

🧾️ Download transcript

Summary

If you feel like your brain's stuck in first gear, losing focus, forgetting simple things, feeling mentally sluggish—you’re not alone. I lived with brain fog for 15 years while building companies in Silicon Valley, and no productivity hack or double espresso fixed it. In this episode, I’ll show you how to clear brain fog at the cellular level by restoring mitochondrial energy, ditching brain-damaging foods, optimizing sleep, and upgrading your nutrition. These are the exact science-backed steps that got me back to feeling sharp, focused, and fully me. Let’s turn your brain back on.


Chapters:

0:00 – Introduction

0:49 – The Root Cause of Brain Fog

1:26 – What Most People Get Wrong

2:20 – How to Fix Your Mitochondria

2:57 – Food: Fuel or Poison

4:48 – The 4 Brain Poisons Killing Your Focus

5:20 – Exercise for Brain Energy (Not Burnout)

7:55 – Brain Fog Supplements That Work


Brain fog supplement: https://shopsuppgradelabs.com/products/brain-101, use code DAVE15


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Transcript

Click on a timestamp to play from that location

0:00.0

You lose your train of thought mid-sentence.

0:03.0

You stare at your phone and forget why you picked it up.

0:06.0

Feel mentally dead by 2 o'clock every day.

0:09.0

We call this brain fog, and it's become so normal that most of us just think it's part of life.

0:15.0

And I thought the same thing.

0:17.0

I spent 15 years in Silicon Valley working in big tech,

0:20.0

and I couldn't remember what I said

0:23.0

in meetings five minutes after I left them. I'd reread the same paragraph four times since I

0:28.2

have no idea what it said, but brain fog isn't laziness, stress, or aging. It's actually a

0:34.8

warning sign that something inside your cells is broken. It's your brain's

0:38.6

energy system breaking down. And unless you fix the root cause, no amount of productivity hacks

0:43.8

are going to save you. Today, I'm going to show you how to fix brain fog at the source.

0:48.7

Because most people think brain fog is about exhaustion. That it's a matter of not getting

0:52.6

enough sleep, working too many hours,

0:54.3

or just needing strong coffee to snap out of it. Now, all those might help, but those aren't the

0:58.4

cause. It's become normal to feel mentally sluggish by 2 p.m. You lose track of conversations,

1:03.8

you stare at your phone, and you just don't know why you even picked it up. You open the

1:08.6

refrigerator. You don't know why you open the door. And the dangerous part is how routine this has become. People don't know why you even picked it up. You open the refrigerator. You don't know why you open the door.

1:16.6

And the dangerous part is how routine this has become. People don't question it. They just assume their brain is slowing down with age or stress, but that's a lie. Brain fog isn't a feeling. It's a

1:22.2

biological breakdown happening inside your cells. Most people attack brain fog with low-grade coffee,

1:32.2

naps or apps that promise productivity, but none of those solve the root problem. And unless you fix the root, no amount of productivity hacks,

1:35.5

neutropic supplements, or motivational speeches is going to help. Your neurons fire

...

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