Lisa Bilyeu: How to hack confidence : 1331

The Human Upgrade: Biohacking for Longevity & Performance

Dave Asprey

Fat, Health & Fitness, Meditation, Biohacking, Lifestyle, Diet, Science, Self-improvement, Fasting, Nutrition, Hacking, Fitness, Brain, Wellness, Education

4.6 • 7.3K Ratings

🗓️ 19 September 2025

⏱️ 72 minutes

🔗️ Recording | iTunes | RSS

🧾️ Download transcript

Summary

Confidence is biology you can hack. In this episode, you’ll see how confidence builds inside your brain, rewires through neuroplasticity, and connects directly to mitochondria, metabolism, and human performance. You’ll get tools that reprogram fear, regulate your nervous system, and turn stress into fuel so you build radical confidence that lasts.

Listen to this classic with host Dave Asprey as he talks with entrepreneur, author, and Women of Impact founder Lisa Bilyeu. Lisa went from a stay-at-home “supporting role” to co-founding Quest Nutrition, scaling it into a billion-dollar company, and running a global media empire. She brings years of lived experience and applied mindset training, making her one of the most authentic voices on confidence, resilience, and leadership in the biohacking world.

You’ll learn how to:

• Hack confidence with the same strategies you use for sleep optimization, fasting, and cold therapy

• Spot biological triggers behind fear, self-doubt, and procrastination

• Use repetition and mindset tools to upgrade brain optimization and neuroplasticity

• Turn stress hormones into growth signals for longevity and functional medicine practices

• Reframe trauma and setbacks as power for resilience and high performance

• Support courage and focus with nootropics, ketosis, supplements, and Danger Coffee

This episode shows you how to treat confidence as a trainable skill, not a personality trait. If you want smarter not harder strategies to master your biology, expand your impact, and live with unshakable resilience, you’ll find them here.

Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living.

New episodes release every Tuesday, Thursday, Friday (audio-only), and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient.

Keywords: Lisa Bilyeu, Radical Confidence, Quest Nutrition, Women of Impact, confidence training, resilience biohacking, mindset reprogramming, courage hacking, fear rewiring, entrepreneurial mindset, human performance, brain optimization, neuroplasticity tools, mitochondria and confidence, trauma resilience, emotional regulation, nootropics for confidence, stress as fuel, leadership confidence, Human Upgrade podcast

Thank you to our sponsors!

EMR-Tek | https://www.emr-tek.com/DAVE and use code DAVE for 40% off.

Resources:

• Lisa’s Website: https://lisabilyeu.com/

• Danger Coffee: https://dangercoffee.com/DAVE15

• Dave Asprey’s BEYOND Conference: https://beyondconference.com

• Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated

• Upgrade Collective: https://www.ourupgradecollective.com

• Upgrade Labs: https://upgradelabs.com

• 40 Years of Zen: https://40yearsofzen.com

Timestamps:

0:00 – Trailer

0:38 – Intro

2:38 – From Housewife to Entrepreneur

17:52 – Building Impact Theory

27:56 – Radical Confidence

39:14 – The No BS Game

44:45 – Finding Purpose

55:34 – Inner Critic & Competence

1:01:10 – Becoming Your Own Hero

1:08:32 – Boundaries & Relationships

1:09:52 – Conclusion

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Transcript

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0:00.0	A lot of people either don't have the confidence or the skills to run a 40-person team. That's actually really hard. I was just like in this purgatory where nothing was bad. Nothing was great. Who am I to complain? So pergator and mundane is where your life is just mundane enough. Like you don't hit rock bottom. They're just going with emotions where they're not asking. Am I living the life I want? Is this actually something that fulfills me?
0:22.2	I went from one day literally shipping bars out of my living room floor to having a 10,000
0:26.7	square foot facility.
0:28.3	We were shipping out over $80 million of product and I had like 40 employees underneath me.
0:33.4	So how did you have the confidence to do that?
0:35.0	I didn't have confidence.
0:36.2	And that's what actually cool.
0:45.5	Okay. So how did you have the confidence to do that? I didn't have confidence. And that's what actually did. If your light environment isn't dialed in, your biology isn't either. And if you're not using light as a performance tool, you're leaving results on the table every single day.
0:51.3	The right light wavelengths unlock recovery, energy, and clarity in ways most
0:56.3	people never tap into. EMR Tech's Krypton UV line puts that power in your hands with red,
1:02.7	near-infrared, UVA, and UVB all in one system. They have something for everyone. From the compact
1:08.4	Krypton Micro and Mini to the modular 606 watt and 1612 watt,
1:13.6	each device lets you choose your wavelengths, your timers, and how deep you want to go with your setup.
1:20.6	I personally use the Ultron. It's a beast. Full body coverage, built-in timers, and high output light from premium components.
1:28.8	Whether you're sinking your circadian rhythm or designing a pro-level light environment,
1:33.7	EMR tech lets you scale it your way with precise control.
1:37.8	Go to EMR-T-EK.com slash Dave and use code Dave for 40% off.
1:47.9	So. dot com slash Dave and use code Dave for 40% off. So many people, even at the highest levels of business, they don't have confidence.
1:52.4	And maybe it shows, maybe you learn to hide it.
1:54.7	But you're going to learn today from Lisa, Bill, you our guest, what it's like to be confident. You might have heard of Lisa.
2:03.4	She's real popular on social media. She has this channel, and she's just one of those women who
2:07.9	radiates confidence. And it's actually refreshing. I know her personally, and her husband, Tom,
	...

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