Groundbreaking Hypothesis Identifies The Biggest Driver Of Alzheimer's Disease with Dr. Richard Johnson

Dhru Purohit Show

Dhru Purohit

Alternative Health, Medicine, Health & Fitness

4.7 • 3.6K Ratings

🗓️ 10 April 2023

⏱️ 149 minutes

🔗️ Recording | iTunes | RSS

🧾️ Download transcript

Summary

This episode is brought to you by Birch Mattress by Helix and InsideTracker. This week on The Dhru Purohit Podcast, Dhru sits down with Dr. Richard Johnson to discuss his revolutionary new hypothesis on the link between fructose consumption and Alzheimer’s disease. Dhru and Dr. Johnson discuss the evolutionary mechanism behind fructose metabolism, insulin resistance, and weight gain that has completely backfired today due to its overconsumption. Dr. Richard Johnson is a professor of medicine at the University of Colorado Denver and has been a practicing physician and clinical scientist for over 25 years. He is internationally recognized for his seminal work on the role of fructose in obesity, diabetes, and now, Alzheimer’s disease. His work also highlights the fundamental role of uric acid (which is generated during fructose metabolism) in metabolic syndrome. He is the author of The Fat Switch and his newest bestselling book, Nature Wants Us to Be Fat. In this episode Dhru and Dr. Johnson dive into: -Dr. Johnson’s new hypothesis on the relationship between Alzheimer’s and fructose consumption (3:06) -The origins of Alzheimer’s (what’s going on in the brain) (14:00) -How modern-day life has hijacked our genetics to make us fat (23:08) -How fructose impacts mitochondrial function (35:22) -Why the body converts glucose to fructose (50:00) -The relationship between salt, dehydration, and fructose production (1:03:03) -How fructose makes us crave more sugar (1:09:23) -Fructose and Alzheimer’s disease (1:11:46) -The importance of strength training for glycemic control and Alzheimer’s prevention (1:30:53) -Sources of fructose in our ancestral diet (1:36:00) -The role of salt and dehydration in obesity (1:46:17) -Hidden “healthy” sources of fructose in the diet (1:58:57) -High-glycemic foods to minimize in the diet (2:00:03) -Umami foods and uric acid (2:07:55) -Dr. Johnson’s thoughts on Saturated fat (2:12:53) Also mentioned in this episode: -The Fat Gene -Could Alzheimer’s disease be a maladaptation of an evolutionary survival pathway mediated by intracerebral fructose and uric acid metabolism? -Study Suggests Fructose Could Drive Alzheimer's Disease (study press release) -Nature Wants Us to Be Fat by Dr. Richard Johnson -The End of Alzheimer's Program by Dr. Dale Bredesen -Drop Acid by Dr. David Perlmutter Birch Mattress by Helix is made out of organic latex, organic cotton, New Zealand wool, and American steel springs. To get 20% off your Birch Living mattress, head over to birchliving.com/dhru today. InsideTracker provides detailed nutrition and lifestyle guidance based on your individual needs. Right now, they’re offering my podcast community 20% off. Just go to insidetracker.com/DHRU to get your discount and try it out for yourself. Hosted on Acast. See acast.com/privacy for more information. Learn more about your ad choices. Visit megaphone.fm/adchoices

Transcript

Click on a timestamp to play from that location

0:00.0	When glucose levels go up, insulin goes up.
0:03.6	But what fructose will do is over time it will increase the insulin even without the glucose having to go up.
0:10.0	It actually induces insulin resistance.
0:13.6	So fructose actually is what's driving insulin resistance.
0:17.6	Glucose is driving insulin.
0:19.6	But it's not insulin resistance. It's just a normal parallel.
0:23.0	Glucose goes up, insulin goes up.
0:24.8	But once you become insulin resistant, you're actually going into a low ATP state.
0:30.8	And that is really what fructose does.
0:34.8	There's a mind-blowing new hypothesis of what could be driving Alzheimer's disease.
0:40.4	And if you want to learn more about this hypothesis directly from the lead researcher who put it out there
0:46.4	and discover ways to potentially lower your risk from this super scary disease,
0:51.2	today's podcast is absolutely for you.
0:54.2	Welcome to the Drew Pro at Podcast.
0:56.2	Each week we explore the inner workings of the brain and the body with one of the brightest minds in wellness, medicine and mindset.
1:03.4	This week's guest is Dr. Richard Johnson, a leading researcher, clinician, and educator on the causes of obesity and diabetes.
1:11.8	And on today's podcast, Dr. Johnson is going to be diving deep into a new hypothesis that he's recently published along with a few of his colleagues
1:20.6	in the Journal of Clinical Nutrition on the topic of Alzheimer's disease and a key type of sugar, fructose,
1:28.2	that could be driving it in modern-day society.
1:31.4	Not only does Dr. Johnson help you understand why he thinks fructose is so problematic,
1:36.2	especially when it comes to the brain, but he also tells you which foods you might want to avoid
1:41.4	or at least greatly minimize in your diet to protect yourself.
	...

Please login to see the full transcript.

Previous episode | Next episode

Disclaimer: The podcast and artwork embedded on this page are from Dhru Purohit, and are the property of its owner and not affiliated with or endorsed by Tapesearch.

Generated transcripts are the property of Dhru Purohit and are distributed freely under the Fair Use doctrine. Transcripts generated by Tapesearch are not guaranteed to be accurate.