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Hi there from CNN. I'm Charlie Drever with the five things you need to know for Tuesday, September 16th.

We start this episode with Israel's military launching a major ground invasion of Gaza City.

That's what two Israeli officials told CNN. And the country's Prime Minister, Benjamin Netanyahu,

says a, quote, intense operation has begun in Gaza.

It's an escalation of the war that defies international condemnation and backlash from

the families of hostages held by Hamas.

According to hospital officials in Gaza, overnight strikes in Gaza City killed at least

37 people.

And as CNN's Paula Hancock explains, it's still not clear how

many civilians are still in the enclave's largest city. We did hear from an Israeli military

official on Monday saying that they believed about 320,000 civilians had left Gaza City, but it's

believed up to 1 million were there originally.

So certainly there are concerns for those that have not managed to leave yet.

This is all happening as a UN commission says that Israel is committing genocide in Gaza,

...