Feeling Tired? This Molecule Could Be Why After 30
Over 50 & Flourishing with Dominique Sachse
Dear Media
4.8 • 864 Ratings
🗓️ 20 April 2026
⏱️ 67 minutes
🧾️ Download transcript
Summary
🎟️ Don’t miss your chance to experience the Behind the Curtain tour LIVE! Grab your tickets now before they’re gone! Get yours here: https://linktr.ee/over50flourishing
In this episode of Over 50 & Flourishing, I sit down with one of the leading minds in longevity science to unpack one of the most talked-about molecules in aging today: NAD.
We’ve all heard the buzz, but what is NAD, and why does it matter so much as we age? From energy and brain function to hormones, skin, and metabolism, this powerful molecule plays a critical role in how our bodies function and declines significantly after our 30s. Dr. Andrew Salzman breaks down the science in a way that actually makes sense, helping us understand what’s really happening inside our cells and how it impacts aging, menopause, and overall vitality.
We also dive into the connection between NAD, inflammation, the microbiome, and cellular energy, and what we can do to better support our bodies as we move through life.
Dr. Andrew Salzman is a Harvard-educated physician and biomedical entrepreneur with more than 30 years of experience in drug discovery. He has published over 170 clinical studies, holds more than 50 patents, and is known for pioneering work in NAD biology, DNA repair, and longevity science. He currently serves as Chief Medical Officer at Wonderfeel, where he focuses on developing science-backed solutions for healthy aging.
Subscribe and save $15 off the one-time price at https://getwonderfeel.com
- Custom Promo Code: FLOURISHING
- Offer: Customers will receive a travel-size, seven-day Youngr™ NMN pouch with their order
- Campaign Duration: April 20–April 27
Keep in Touch:
- Website: https://dominiquesachse.tv/
- Book: https://dominiquesachse.tv/book/
- Insta: https://www.instagram.com/dominiquesachse/
- Facebook: https://www.facebook.com/DominiqueSachse/
- TikTok: https://www.tiktok.com/@dominiquesachse?lang=en
- YouTube: https://www.youtube.com/@dominiquesachsetv
Have a question for Dominique? Submit it here for a chance to have it answered on the show! https://forms.gle/MpTeWN1oKN8t18pm6
Interested in being featured as a guest? Please email courtney@dominiquesachse.tv
We want to make the podcast even better. Help us learn how we can: https://bit.ly/2EcYbu4
Please note that this episode may contain paid endorsements and advertisements for products and services. Individuals on the show may have a direct or indirect financial interest in products or services referred to in this episode.
Produced by Dear Media.
See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Transcript
Click on a timestamp to play from that location
| 0:00.0 | The following podcast is a dear media production. |
| 0:13.1 | Welcome to today's episode of Over 50 and flourishing. So we've all heard the buzz about |
| 0:17.9 | NAD for aging gracefully, but let's talk about what this actually |
| 0:21.6 | looks like when we're in the thick of menopause. This isn't just about a few gray hairs. |
| 0:26.6 | It is a total metabolic and hormonal overhaul that can leave your skin, your sleep, and your |
| 0:32.5 | energy feeling completely whacked. Our NAD levels naturally take a dive after our 30s, but during menopause, |
| 0:40.5 | this drop hits differently. When your cellular fuel is low, right, as your body is working |
| 0:46.2 | over time to navigate these changes, everything feels twice as hard. That's why I love the feeling |
| 0:52.6 | that I get using Wonderfeel younger NMN, and I know you will too. |
| 0:57.4 | I really appreciate that the Wonderfield team did all the hard work to bring us a formula that |
| 1:02.7 | actually moves the needle, combining clinically backed 900 milligram dose of NMN with powerful compounds built to defend NMN on its path to yourselves. |
| 1:14.6 | It's a simple daily habit that helps you reclaim your steady energy and resilience, |
| 1:19.3 | making this transition feel less like a hurdle and more like a new chapter. |
| 1:23.8 | So welcome to the podcast, Harvard Med School, Yale and Columbia grad, medical doctor, professor, inventor, and chief medical officer of Wonderfield, Dr. Andrew Salsman. |
| 1:41.3 | Andrew, it is so good to have you in studio with me on over 50 and flourishing. |
| 1:47.1 | Thank you. |
| 1:47.6 | Something tells me that by the end of this podcast, every woman who is listening |
| 1:53.1 | is going to feel empowered to flourish. |
| 1:56.4 | I teed you up. |
| 1:57.8 | I mean, your intro, your background, Harvard Med School, Yale, Columbia grad, I mean, you're |
| 2:06.0 | the smartest person that's ever been in this room. |
| 2:08.3 | Okay, can I just start off by saying that? |
... |
Please login to see the full transcript.
Disclaimer: The podcast and artwork embedded on this page are from Dear Media, and are the property of its owner and not affiliated with or endorsed by Tapesearch.
Generated transcripts are the property of Dear Media and are distributed freely under the Fair Use doctrine. Transcripts generated by Tapesearch are not guaranteed to be accurate.
Copyright © Tapesearch 2026.