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Real Life Pharmacology - Pharmacology Education for Health Care Professionals

Lisdexamfetamine Pharmacology Podcast

Real Life Pharmacology - Pharmacology Education for Health Care Professionals

Eric Christianson, PharmD; Pharmacology Expert and Clinical Pharmacist

Education, Health & Fitness, Medicine

4.9773 Ratings

🗓️ 14 September 2023

⏱️ 11 minutes

🧾️ Download transcript

Summary

On this podcast episode, I discuss lisdexamfetamine (Vyvanse) pharmacology, adverse effects, drug interactions, and much more.

Lisdexamfetamine is a stimulant medication that is used in the management of ADHD.

Stimulants like lisdexamfetamine can increase heart rate, raise blood pressure, and suppress appetite.

Lisdexamfetamine is a schedule 2 controlled substance and has a high potential for abuse and dependence.

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Transcript

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0:00.0

Hey all, welcome back to the Real Life Pharmacology podcast. I'm your host, pharmacist, Derek Christensen.

0:05.3

Thank you so much for listening today. So always go check out Real Life Pharmacology.com. Get your

0:11.4

free 31 page PDF on the top 200 drugs. It's a great study guide. It's a great review out in practice.

0:20.0

Definitely go take advantage of that. Simply an email is going to get you

0:23.1

access to that. And then we've also get you emails when we've got new content available as well,

0:28.6

such as this podcast, for example. So the drug of the day today is Lizdexamphetamine.

0:36.4

Brand name of this medication is Vivance.

0:40.3

This is a CNS stimulant.

0:44.0

It is a sympathamomimetic agent.

0:48.0

It is primarily going to release norepinephrine and dopamine.

0:54.0

And it is going to be used in ADHD,

0:56.9

and it also is indicated in binge eating disorder.

1:02.7

Primary dosing range, initial dosing can be in the 10 to 30 milligram range.

1:10.5

Obviously, if we're using potentially in pediatrics,

1:14.5

younger patients, smaller patients, we're probably going to start more conservatively there. In adults,

1:20.4

you may see 30 milligrams started on a regular basis there, up to typically a max of 70 milligrams per day. I will say there is

1:32.0

some caution with renal impairment and recommended max dose in a patient with 15 mils per minute, 30

1:41.4

mils per minute range. That maximum dose is recommended to be 50 milligrams per day.

1:47.6

In patients with end-stage renal disease and or

1:52.1

granting clearance less than 15 mils per minute,

1:56.6

we're looking at a maximum of 30 milligrams per day.

2:00.5

So let's get into some of the risks and adverse effects with this agent.

...

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