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Everyday Wellness: Midlife Hormones, Menopause, and Science for Women 35+

Ep. 596 “When Estrogen Drops, Your Gut Feels It” – How Hormones Slow Digestion in Midlife | Menopause, Perimenopause & Gut Health

Everyday Wellness: Midlife Hormones, Menopause, and Science for Women 35+

Cynthia Thurlow

Science, Life Sciences, Health & Fitness, Nutrition, Alternative Health

4.71.2K Ratings

🗓️ 21 May 2026

⏱️ 27 minutes

🧾️ Download transcript

Summary

Welcome to today’s Midlife Minute. Today, we’re exploring bloating, constipation, and various other midlife gut woes.  Stay tuned as I clarify how midlife changes the gut narrative and review the evidence about how to get things moving again. IN THIS EPISODE, YOU WILL LEARN: Why your gut motility changes in midlife How menopause influences the gut-brain connection Why various types of constipation require different interventions How changes in your gut bacteria affect the way your gut functions in menopause How different types of fiber can either help or worsen constipation symptoms, depending on the type of constipation  The main types of constipation, and how they differ  How estrogen therapy may influence bowel regularity, and why the route of administration matters Lifestyle habits that can stimulate bowel movements Why bloating tends to occur in midlife Connect with Cynthia Thurlow   Follow on X, Instagram & LinkedIn Check out Cynthia’s website. Submit your questions to support@cynthiathurlow.com Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow.  Cynthia’s Menopause Gut Book is on presale now! Cynthia’s Intermittent Fasting Transformation Book The Midlife Pause Supplement Line Links: 1. Menopause Is Associated with an Altered Gut Microbiome and Estrobolome, with Implications for Adverse Cardiometabolic Risk in the Hispanic Community Health Study/Study of Latinos 2. The Intestinal Microbiome and Estrogen Receptor–Positive Female Breast Cancer  3. Estrogen–gut microbiome axis: Physiological and clinical implications 4. Menopausal shift on women’s health and microbial niches 5. Gut microbiota has the potential to improve health of menopausal women by regulating estrogen 6. Gut-microbiota-targeted diets modulate human immune status 7. Effect of female sex hormone supplementation and withdrawal on gastrointestinal and colonic transit in postmenopausal women 8. Constipation and diarrhea during the menopause transition and early postmenopause: observations from the Seattle Midlife Women’s Health Study 9. Estrogen Rather Than Progesterone Cause Constipation in Both Female and Male Mice 10. Rome IV Criteria 11. Gut-Directed Hypnotherapy for Irritable Bowel Syndrome: A Systematic Review and Meta-Analysis  Gut-Directed Hypnotherapy for Irritable Bowel Syndrome: A Systematic Review and Meta-Analysis (PubMed) 12. Randomised clinical trial: the efficacy of gut-directed hypnotherapy is similar to that of the low FODMAP diet for the treatment of irritable bowel syndrome 13. Gut-directed hypnosis and hypnotherapy for irritable bowel syndrome: a mini-review 14. Review article: gut-directed hypnotherapy in the management of irritable bowel syndrome and inflammatory bowel disease

Transcript

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0:00.0

Welcome to Everyday Wellness Podcast.

0:04.0

I'm your host, Nurse Practitioner Cynthia Thurlow.

0:07.0

This podcast is designed to educate, empower, and inspire you to achieve your health and wellness goals.

0:13.0

My goal and intent is to provide you with the best content and conversations from leaders in the health and wellness industry each week and impact over a million lives.

0:28.9

This is the start of a new Thursday series called The Midlife Minute that is really designed to address listeners questions in a little bit longer

0:40.1

length of time and or deeper dive into topics.

0:44.8

Ideally, we're going to keep these podcasts under 20 minutes.

0:48.2

Occasionally, we may go over to 30, but I'm trying to reinforce some key concepts and ensure that I'm addressing listeners' questions

0:58.2

in a way that's really helpful.

1:00.2

So the questions that I will be addressing topics are going to be items that I'm being

1:04.6

asked over and over and over again.

1:06.3

I hope you enjoy this series.

1:07.8

Please share with your friends.

1:09.5

And as you know, you can always send your

1:11.6

questions to support at cynthia thurlow.com. I appreciate each and every listener.

1:20.0

Welcome to the latest midlife minute today is going to be talking about bloating, constipation,

1:26.0

and other midlife gut woes. I've got lots of questions

1:30.8

around constipation and bloating and let's get to it. Let's talk about the constipation conversation

1:36.3

no one is having with you. You're eating well, drinking water, staying active, and still

1:40.7

nothing is moving. Here's why midlife changes the narrative around our gut

1:45.9

and what the evidence actually says about getting things moving again. We know women are three

1:51.7

times more likely to report constipation than men. 40% of perimenopausal women report new or

...

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