4.8 • 827 Ratings
🗓️ 6 August 2025
⏱️ 107 minutes
🧾️ Download transcript
In this episode of Iron Culture, Helms and Trex have a lengthy discussion about the ECA stack and yohimbine. The history, the mechanisms, the regulatory changes, the practical applications – you name it, they cover it. Don’t miss this episode if you have an interest in fat loss, stimulants, or dietary supplementation in general.
Also, be sure to check out the newest issue of the MASS Research Review! Learn more at massresearchreview.com
Time stamps
0:00 Intro
4:18 New issue of the MASS Research Review
10:42 Helms contest prep update
13:15 The history of the ECA stack and supplement regulation
30:07 Ephedra vs Ephedrine
35:31 Why people took ephedrine / ECA stack
36:30 Trends in PED use over time
45:00 Research on the ECA stack
50:58 Banning lifters for stimulant use
53:15 Effects of ephedrine + caffeine on metabolism and fat loss
1:02:44 What does aspirin really add to the ECA stack?
1:13:00 Do NSAIDs blunt hypertrophy?
1:21:25 How yohimbine works (and yohimbe vs yohimbine distinction)
1:31:10 Regulatory status of yohimbine
1:32:58 Practical applications
Click on a timestamp to play from that location
0:00.0 | Hello everybody. Welcome back to Iron Culture. It is me, Eric Drexler here with the Dr. Eric Helms. This is Iron Culture presented by the Mass Research Review. It's Monday night, 7 p.m., which means we are live. Helms, how we doing tonight? |
0:28.5 | I'm doing well, man. We're seeing each other. I'm enjoying it. We had a good last episode, |
0:33.7 | and you know what? Things are going well in mass. I'm excited about the issue that just dropped a few days back and... Oh, one done with my books big one almost done with |
0:38.9 | your books okay yeah do you have a date circled on the calendar honestly i i pretty much do |
0:47.5 | because we're down to just like half of an appendix for the uh the training book and minor modifications to the behavior and lifestyle final chapter. |
0:58.1 | And then it's, so I'll put it this way. |
1:00.9 | End of this week is what I've got circled on my calendar for being done writing entirely. |
1:06.8 | And then it'll be moving on to like making figures discussing whether we want to release it just through |
1:12.6 | uh amazon this year and just send pdfs to the you know the prior purchasers who already had the second |
1:18.7 | edition and get it on kindle or you know like there's there's stuff to discuss and things to do so it's |
1:23.4 | not going to launch at the end of this week it'll probably come out and also yeah we need to have a meeting of like when's the best launch date but yeah it's not going to launch at the end of this week. It'll probably come out. And also, yeah, we need to have a meeting of like, when's the best launch date? But yeah, it's, uh, it's right there. And you know what? I'll be able to die happy man after that's written. I'll tell you what. Yeah. Is that also, you have a date schedule for that too? Or are you just going to? Yes. Okay. It took me six years before i got so annoyed i needed to |
1:46.8 | rewrite no five years before i got so annoyed no annoyed i needed to rewrite this book and i don't want to |
1:52.9 | rewrite it again so i'm thinking sometime in the next five years i'm i'm pretty happy with how my |
1:59.0 | life's gone yeah well that's good that's where you want to be at the end of life is saying, you know what? I did what I wanted to do. I'm ready to go. And I feel like within that time frame, you're going to be close to, you know, typical life expectancy anyway. So why put it? You don't need to be greedy. I don't want to be greedy. |
2:22.2 | And there's a lot of life that's out there, and I think other people deserve more than me at this stage. |
2:29.3 | And not to mention, I'm starting to question what my actual age is because I think I'm 42. |
2:36.3 | But then based upon the references that you, Zerdos and Lauren think I will get, |
2:42.1 | and also sometimes the quite like specifically stated years that I have been alive, |
2:45.3 | which sometimes include the early 1900s and the 1800s, |
2:48.2 | make me think that I might be 130. |
2:56.3 | And it's just that I have some unique form of cognitive decline where I don't lose all memory, but I just only keep the last 42 years of memory. So I think I'm 42, but I'm |
3:03.2 | actually 130. And maybe I've thought I'm like, you just run out of space and like you just kind of like your iPhone. It's like, well, it's going to delete your old stuff. I think that's what's happening. So. So Helms, let me, uh, clue you in on something here. This is just the way the world works. Um, I hate to be the one that has to break this to you, but you can see behind me. |
... |
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