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Finding Genius Podcast

Coral Disease Symptoms and Successes: Researcher Laura Mydlarz Focuses on Host Defense

Finding Genius Podcast

Richard Jacobs

Medicine, Health & Fitness

4.41K Ratings

🗓️ 24 September 2020

⏱️ 37 minutes

🧾️ Download transcript

Summary

Professor Laura Mydlarz was fascinated with ocean life from a young age and now runs a marine biology lab at a university. After studying tropical ecosystems and coral reefs in college, she never looked back.

She brings her explorations across the Caribbean to listeners and explains

  • How coral reefs and their formation depend on their algal symbiont for their sustenance,
  • Why pathogens affect the photosynthetic ability of the symbionts, and
  • How learning to turn on mitochondrial rescue modes of coral cells might be one path to effective treatment.

Dr. Laura D. Mydlarz is a professor of biology and an associate dean of the College of Science at the University of Texas in Arlington. She shares her passion for ocean life with listeners and discusses the intricate and ancient immunity of coral reefs and their importance to ocean ecology.

She notes that scientists often focus on the pathogen when consider coral disease treatment, but she focuses more on understanding what the host is doing to fight disease and studies coral immunity systems.  She looks mainly at reactions to coral infectious diseases caused by bacteria, fungus and even some pathogenic viruses; corals face such pathogens just like humans.

However, she explains, corals are a much more ancient life form and they work with one type of immunity—innate—whereas humans can use innate and acquired immunity. However, their immunity is still much more complex than scientists thought. She describes this intricate immunity, one that must allow this other living organism, the symbiont algae, inside it without fighting it.

Furthermore, the healthy algae is contributing a lot of resources and food to the coral and pathogens can affect both life forms, leading to coral reefs dying. They need all the energy they can get to mount an immune defense, and suffer when, for example, the symbiont is no longer able to photosynthesize because of the color changes from disease. She explains coral ecology in further detail and how issues like climate change play a role.

Finally, she describes her more immediate goals, which include understanding the proper or healthy immune response of coral. Thus far, they've found interesting implications regarding mitochondrial defense systems and melanin presence. 

To find out more, see her lab's website: themydlarzlab.com

Available on Apple Podcasts: apple.co/2Os0myK

Transcript

Click on a timestamp to play from that location

0:00.0

Forget frequently asked questions common sense common knowledge or Google how about advice from a real genius

0:06.8

95% of people in any profession are good enough to be qualified and licensed 5% go and beyond. They become very good at what they do.

0:15.1

But only 0.1% are real Jesus.

0:18.3

Richard Jacobs has made it his life's mission to find them for you.

0:22.4

He hunts down and interviews geniuses in every field, sleep science, cancer, stem cells,

0:27.2

ketogenic diets, and more.

0:28.8

Here come the geniuses.

0:30.4

This is the Finding Genius Podcast.

0:33.0

That is Richard Jacobs.

0:35.0

Hello, this is Richard Jacobs with the Finding Genius Podcast.

0:41.0

I have Laura MidlARS.

0:42.0

She's a professor in the Department of Biology. My name, Gene Niest Podcast. I have Laura Midlaris.

0:42.8

She's a professor in the Department of Biology

0:45.4

and Associate Dean of the College of Science

0:47.6

at University of Texas at Arlington.

0:50.1

And she obtained a PhD in 2004

0:52.2

from University of California at, well it says, Santa, I don't know if it's

0:57.1

Santa Cruz or Santa Barbara, but my University, Santa Barbara, Santa Barbara,

1:00.3

Santa Barbara, okay, oh, beautiful place.

1:03.0

Conducted postdoctoral research at Cornell University,

1:06.1

and she studied coral diseases and coral immune responses there.

1:10.1

Now, her own lab at U.S. Arlington, she's trained 10 graduate students and 50 undergraduate students.

...

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