Big Ideas 2026: The Enterprise Orchestration Layer
The a16z Show
a16z
4.2 • 1.2K Ratings
🗓️ 23 December 2025
⏱️ 22 minutes
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| 0:00.0 | 2026 is when multiplayer mode comes into gear. |
| 0:04.0 | If you have a bunch of agents autonomously working, isn't there potential for a huge, you know, multi-agent cascade of failures? |
| 0:11.0 | There's a lot of narrative around AI helping automate work and reducing cost. |
| 0:16.0 | But I think in instances where AI is actually reinforcing the business model in driving revenue, there's really |
| 0:21.7 | no limit to the amount that customers may want to adopt that technology. |
| 0:26.2 | It's not AI that's the competition. It's your competitors using AI. |
| 0:33.0 | Every year, we step back and ask a simple question. What will builders focus on next? |
| 0:38.3 | Our 26 big ideas bring together the themes our investing teams believe will shape the coming |
| 0:42.7 | year in tech. This episode is built around one big idea. AI is becoming an orchestration layer |
| 0:48.5 | inside the enterprise. Not a collection of standalone tools, a coordinated system of agents that can |
| 0:53.7 | plan, analyze, and execute work across departments and software. |
| 0:57.0 | You'll hear four perspectives of what changes when AI starts running the workflow, |
| 1:01.0 | how organizations extract context, |
| 1:04.0 | why legacy replacement accelerates, |
| 1:06.0 | what multiplayer AI looks like in practice, |
| 1:08.0 | and what makes these systems commercially defensible. |
| 1:13.6 | To understand the shift, we start with the Enterprise Wide View. |
| 1:16.6 | Seema Amble argues that the move from experimentation to coordinated multi-agent systems |
| 1:21.6 | will force organizations to extract tacit knowledge from documents, processes, and people's heads, |
| 1:26.6 | turning it into usable |
| 1:28.2 | operational context. Here's SEMA. |
| 1:31.8 | Hi, I'm Sema Amble, a partner on our apps investing team. My 2026 big idea is that AI will create |
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