0:00.0	Hey all, welcome back to the Real Life Pharmacology podcast.
0:04.1	I'm your host, pharmacist, Eric Christensen.
0:06.2	Thank you so much for listening today.
0:08.7	Go check out Real Life Pharmacology.com.
0:12.0	You won't be disappointed.
0:13.3	I've got a free 31-page PDF on the top 200 drugs.
0:17.5	It's a great little study guide.
0:18.8	I throw in some of the most common clinical practice
0:23.1	things you'll see. And if you are preparing for board exams and things like that, I also throw in
0:28.6	a lot of top clinical pearls that you might often be tested on. So definitely go check that out,
0:36.5	get it for free just for subscribing to the podcast. We'll get
0:40.7	you emails when we've got a new podcast available and all that sort of stuff. So again, real-life
0:45.6	pharmacology.com. Go find that free PDF on the top 200 drugs. Again, 31 pages. So I can't,
0:54.0	can't miss it. With that, let's get into the drug of
0:58.0	the day today. Amatryptylene. A brand name of this medication is Ellaville. It is an older
1:06.3	antidepressant. More specifically, it's a tricyclic antidepressant. Mechanistically, what tricyclics do
1:16.5	is they inhibit the re-uptake of serotonin and norephenephrine. So obviously, we've heard serotonin in the
1:25.7	past talking about SSRIs and things like that.
1:30.3	So you could imagine if we're increasing serotonin in the brain that it's going to help for depression.
1:38.8	And ultimately a drug like amatryptylene when it first came out many, many years ago,
1:43.8	it was used for depression
1:46.3	prior to the advent of the SSRIs so from a technical standpoint it is classified as an antidepressant
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