Hey all, welcome back to the Real Life Pharmacology podcast.

I'm your host, pharmacist, Eric Christensen.

Thank you so much for listening today.

Go check out Real Life Pharmacology.com.

You won't be disappointed.

I've got a free 31-page PDF on the top 200 drugs.

It's a great little study guide.

I throw in some of the most common clinical practice

things you'll see. And if you are preparing for board exams and things like that, I also throw in

a lot of top clinical pearls that you might often be tested on. So definitely go check that out,

get it for free just for subscribing to the podcast. We'll get

you emails when we've got a new podcast available and all that sort of stuff. So again, real-life

pharmacology.com. Go find that free PDF on the top 200 drugs. Again, 31 pages. So I can't,

can't miss it. With that, let's get into the drug of

the day today. Amatryptylene. A brand name of this medication is Ellaville. It is an older

antidepressant. More specifically, it's a tricyclic antidepressant. Mechanistically, what tricyclics do

is they inhibit the re-uptake of serotonin and norephenephrine. So obviously, we've heard serotonin in the

past talking about SSRIs and things like that.

So you could imagine if we're increasing serotonin in the brain that it's going to help for depression.

And ultimately a drug like amatryptylene when it first came out many, many years ago,

it was used for depression

prior to the advent of the SSRIs so from a technical standpoint it is classified as an antidepressant

...