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The following discussion is for educational purposes only and is not intended to diagnose or

treat any disease. Please do not apply any of this information

without first speaking with your doctor. Now let's head to the show. Hey everyone, welcome back. This is Dr.

Michael Ruchel. I am a clinical researcher, practicing clinician, and an adjunct professor at the

University of Bridgeport with a focus and a passion

for natural health solutions, mainly gut health, as someone who suffered from poor gut health

myself. And today I'm very excited to share with you a paper from Gregor and colleagues

that helps us understand how altered stress hormones, anxiety and depression, poor sleep and fatigue

all intersect with gut health and how probiotic therapy might be able to help all of the above.

So let's jump into the paper.

Again, excellent paper appearing hot off the press, January

2023 in neurogastroenterology and motility. And here is the quick rundown on the design,

randomized control trial with about 50 patients receiving one billion CFU per day of a two-strain

bifidobacterium longum and about 50 healthy controls what they found recap and then will unpack

improvements in ibs anxiety depression sleep quality and cortisol levels so let's unpack a little bit

further at baseline what you're seeing here is the cortisol awakening response now in healthy

physiology we should see a fairly robust amount of cortisol released in the morning.

This is so you wake up and you can be attentive and get out of bed and not feel like you're dragging all morning.

In fact, an inversion of cortisol output can lead to daytime fatigue and then nighttime insomnia. This is part of what you're

...