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Beauty Bytes with Dr. Kay: Secrets of a Plastic Surgeon™

776: Biohacking & Female Longevity: Secrets of the World's Most Measured Woman with Kayla Barnes

Beauty Bytes with Dr. Kay: Secrets of a Plastic Surgeon™

Kay Durairaj, MD, FACS @beautybydrkay

Business, Fashion & Beauty, Health & Fitness, Arts, Management & Marketing, Medicine

4.9608 Ratings

🗓️ 6 November 2025

⏱️ 52 minutes

🧾️ Download transcript

Summary

Join Dr. Kay and renowned female longevity expert Kayla Barnes for a comprehensive discussion on optimal health, moving far beyond "normal" lab ranges to an optimal state. Kayla breaks down essential longevity strategies, from tailoring sleep and exercise protocols to the female cycle and structuring supplements into three categories (baseline, protocol-based, and longevity molecules), to pursuing advanced testing like NMR panels and Homa IR to decode health data. The episode explores cutting-edge therapies like Hyperbaric Oxygen (HBOT) for enhanced healing and blood flow, and Therapeutic Plasma Exchange (TPE) for reducing the total toxic burden. Finally, Dr. Kay and Kayla align on an approach to aesthetic longevity that advocates for a moderated use of pure core neurotoxins like Xeomin in combination with powerful collagen biostimulation and DNA-repairing molecules, such as polynucleotides, for true inside-out rejuvenation.

Transcript

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0:00.0

All right. So today on the podcast, we're interviewing Kayla Barnes, who is an amazing biohacker,

0:20.3

entrepreneur, and boss babe, and Kayla's

0:22.8

going to teach us about all kinds of things. Kayla, what will you teach us about biohacking and

0:27.5

longevity? So we're definitely going to cover the basics for females specifically, but we're

0:32.6

also going to go into advanced biohacks that I've done, things like stem cells, therapeutic

0:36.5

plasma exchange, hyperbaric

0:38.0

oxygen, and how we might be able to use these protocols to benefit our female biology.

0:43.9

I love it. Love that. You have the hyperbaric chamber right behind you, too. Yeah. Do you like that?

0:53.3

What brand? It's been good and reliable. Yeah love it it's a one base um so dr scott

0:58.9

shear is like my consulting hyperbaric physician so he's a partner in this company so just makes

1:04.0

a lot of sense and the customer sports really good comfortable i've really enjoyed it love it. And then I can introduce you as a certified

1:13.2

brain health coach. You can. I mean, I'm not really leaning into that. I would rather just,

1:17.9

you know, have it be like a longevity. I mean, I am one, but I don't see any, I don't see any

1:22.6

clients or anything like that. So ideally just, you know, female longevity expert, um, that's ideal for me.

1:30.5

Okay, good. And do you still work with the, the wellness space? I owned it, but I exited. So,

1:36.3

um, yeah, we can just say co-found. If you want to include that, you can say co-founded one of the

1:41.1

most innovative longevity medicine clinics. I would leave the name out of it just because I'm no longer associated, but that's new. Okay, gotcha. Yeah, I owned and operated it for like six years. So incredible. Is that a good business market for you? Great business market. I mean, I was completely obsessed with it. Um, so brought me lots of joy. The business is in Ohio, though,

2:03.3

and, you know, living in L.A. and not living in Austin, it's just, I'm not there to be the operator anymore.

2:08.5

And it's not, I wanted to grow it really quick. And my partner had different plans. So just

2:12.8

doesn't make most sense for me now. Okay. Well, I, I, um, can just do kind of a most general, more general intro.

2:21.2

Perfect. And then do you have about 30, 40 minutes, hopefully? Yeah. Okay, perfect. Here we go.

2:27.3

I'm going to just make sure the recording is on. Perfect. Well, hello, hello, guys. You're listening to Beauty Bites with Dr. Kay, Secrets of a Plastic Surgeon,

...

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