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Energized with Dr. Mariza

647: Hormone Optimization Therapy (HOT) Isn't Your Mom's HRT + It's One Of The Best Strategies For Longevity with Dr. Amy Killen

Energized with Dr. Mariza

Dr. Mariza Snyder

Medicine, Health & Fitness, Alternative Health

4.8 • 974 Ratings

🗓️ 23 May 2025

⏱️ 66 minutes

🧾️ Download transcript

Summary

The research is so clear… if you want to speed up your biological age, don’t use hormones.  You can be so healthy and dialed in with your habits, but even that won’t stop your hormones from inevitably plummeting in midlife.  That’s why Dr. Amy Killen joins the show to dive into the realities of women’s health in midlife and how hormone replacement can be a game-changer. This conversation sheds light on what’s really happening inside your body in midlife—and what you can do about it!  Dr. Amy breaks down how hormone replacement therapy (HRT), targeted supplements, and strategic lab testing can be huge for your energy, cognition, and longevity.  We’ll also cover the lifestyle changes that truly move the needle in midlife, and how to stay proactive instead of stuck in “default mode.” If you’ve ever felt like you’re doing everything right but still struggling, this episode will make you feel seen and offer real solutions. It’s time to feel inspired, empowered, informed, and ready to take ownership of your midlife health journey!  Amy Killen, M.D. Dr. Amy Killen is a leading physician in regenerative and hormone optimization medicine, specializing in women's health. As an emergency physician turned longevity specialist, she combines treatments like stem cell therapy, hormone optimization, and peptides with practical lifestyle wisdom. She’s the Chief Medical Officer of Humanaut Health and founder of the Human Optimization Project.  IN THIS EPISODE Why estrogen MATTERS  Prioritizing movement for longevity  Day-to-day non-negotiables that move the needle  Supplements for energy and mitochondrial health  The link between HRT and longevity in women  Addressing common myths around perimenopause and HRT  The importance of functional lab tests and screenings  QUOTES “You could be so dialed in with your lifestyle, with your mindset, with your supplements, your everything, and you'll still have declining estrogen and progesterone.”  “Start working on the hormones. It can help with the drive to do the lifestyle things. And I've seen that a lot.” “We can increase human lifespan in women with these hormones and they're very inexpensive, yet less than 5% of women have access [to them].” RESOURCES MENTIONED Dr. Amy’s Website  *Join Dr. Amy’s Newsletter here and get her FREE Supplement Guide! Dr. Amy’s Instagram  Dr. Amy’s Facebook  Dr. Amy’s Female-focused supplement product: HOP Box  RELATED EPISODES  #605: Breaking the HRT Confusion: The Truth Behind Hormone Replacement Therapy for Perimenopausal Women with Karen Martel 579: Hormone Replacement Options and Hormone Testing for Women in Midlife + Self Advocacy for Optimal Health with Esther Blum #576: How to Build Bone, Muscle, Tendon, and Metabolic Resilience in Perimenopause and Menopause with Dr. Vonda Wright #557: What Every Women Needs to Know About Hormone Replacement In Their 40s and Beyond with Felice Gersh

Transcript

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0:00.0

Testosterone is so good for motivation. In men and women, it's so good for like that drive,

0:07.8

that like, I want to go do something. And when we lose it, you can kind of get stuck on the couch

0:12.4

and you can kind of get stuck in this like laxadaisical kind of blah. Or having depression or

0:17.4

anxious. And so, you know, sometimes when we start working on the hormones,

0:22.2

it can help with the drive to do the lifestyle things. And I've seen not a lot. Like, I don't think

0:27.3

it's an either or. I think it's both. And I think you can do them at the same time, but they can

0:31.3

feed off of each other. Welcome back to the energized with Dr. Marisa podcast.

0:52.7

I'm your host, Dr. Marisa, and I'm here to help you rock your hormones, optimize your metabolic health, and feel energized in your body so that you can age powerfully and wake up feeling amazing in your body for many years to come.

1:01.7

Let's jump on in. Hey, one more thing. Did you know that one of the biggest nutrient deficiencies that I see in people, especially women, is a magnesium deficiency.

1:08.0

It's because we burn through this super mineral so quickly. Now, this powerful

1:12.0

mineral packs a massive punch because magnesium is involved in over 600 reactions in the body.

1:17.4

Now, it is your best friend if you need more energy, better sleep, a faster metabolism,

1:21.9

improve digestion, and not to mention happier periods. And you can quickly replenish your magnesium levels

1:28.5

with my essentially whole magnesium restore supplement

1:31.4

made with my favorite form of magnesium, magnesium glycinate.

1:35.6

Use promo code podcast and get 10% off your entire order

1:39.6

at Dr.marisa.com slash magnesium.

1:42.8

Now, I'll have the link in the show notes for this episode to make it easy.

1:46.1

Go and try it out today.

1:51.2

Fun fact.

1:52.7

Or maybe not so fun.

1:54.7

Did you know that only 4 to 5% of menopausal women are on bioidentical hormone replacement therapy.

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