312. How Blood Volume Impacts Performance and Adapts Fast, The Scary Potential of Lactate Supplementation, The True GOAT, and The Circle Pit!
Some Work, All Play
David Roche and Megan Roche
4.8 • 2.1K Ratings
🗓️ 26 May 2026
⏱️ 83 minutes
🧾️ Download transcript
Summary
We basked in some amazing news before this great episode! The main topic was a breakdown of one of the most important elements of performance and health: blood volume.
Studies show that blood volume can seem to act as a synonym for fitness, with one finding that 6 weeks of training gains can be reversed with a phlebotomy that returns blood volume to baseline levels. Positive adaptations can happen in a few days, and it clearly matters for performance. If any other intervention worked like that, you’d assume everyone would be talking about it all the time. But blood volume is not discussed often! We pull back the curtain on the science.
We also talked about a new review article on exogenous lactate supplementation. It might be a brave new world in the next 5 years, but right now there are more questions than answers. We speculate!
And this one was full of cool topics! Other topics: the shockingly good news Megan has received in recent heart tests, our disdain for the Enhanced Games, recent age group doping news, the Satisfy Circle Pit, the true GOAT of endurance, running v. biking, uphill treadmill workouts, and lots more.
Yes, David actually hit himself for a joke on this episode. Podcasts are definitely the medium for physical and visual comedy.
We love you all! HUZZAH!
-David and Megan
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Transcript
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| 0:00.0 | Woohoo. Welcome to the Some Work All Play podcast. We are so happy to do with you today. Happy Tuesday. It's Tuesday. And I can't stop grinning on this Tuesday. Oh my goodness. I know where this grin's coming from. It's lighten up right now. I can't stop. Best vibes ever to start a podcast. So if our listeners have been around for a little bit, Megan's been going through hard issues for five years now. It's been such a journey. You've been so courageous through it all. And you've told your story through it all. And two weeks ago, you described your most recent trip to the hospital. Your three-day stay at the amazing Airbnb, Boulder Community Health. Yeah, Boulder Community Hospital really kind of is like an Airbnb. It had catered food. |
| 0:37.9 | Actually, that goes above and beyond an Airbnb. You even had a toothbrush for us, the perfect kind. Yeah, honestly, when you have two small kids, it's a great getaway. You know, I thought about that for a minute and then I was the one that was being woken up every three hours from retroponin blood draws and I was like, get me out of here. It's pretty nice for me. |
| 0:53.2 | Is what I'm saying? |
| 0:53.9 | At first it was like 9 o'clock at night and I was reading a book in bed and |
| 0:56.6 | I was like gee this is peaceful and then they came in over and over and over again and I'm like you know yeah not so much and when your heart goes to VTAC in the corner it's not necessarily a fun thing and you have an 8 million PVCs and all that. |
| 1:09.3 | So let's give them an update. |
| 1:11.2 | You can take the reins here, Megan. |
| 1:12.6 | I got good heart news last week. |
| 1:14.8 | I'm like, And you have 8 million PVCs and all that. So let's give them an update. |
| 1:11.2 | You can take the reins here, Megan. I got good heart news last week. My EKG normalized, which was awesome. I did so many tests. And I feel like I was waiting for them. They took a long time to come back. Yeah. It's just so remarkable. So three weeks ago, we were in the hospital. And, you know, I was there with you as the doctor said, you don't just need to retire. |
| 1:30.1 | You're probably never going to run again. And this was before a number of tests were being done. And the assumption was that some of these tests would come back bad with findings. Just given the, like, the trajectory of some of metroponin levels in EKG and everything that was happening. It was like, clearly my heart was not in a good place. Yeah. If this was a show of Dr. House, it would be, girl fucked. And you know, you were so open. And that's how we recorded that episode, basically, is this understanding that this could be a long-term end-of-your-care type situation. Which I don't love doing at the same time because I'm like, I don't want to scare people. You know, it's- Oh, Megan, I was in the hospital with you. I've been in these cardiology appointments with you over time, too. It's not the first doctor that told you to stop. I know, but it's like, I feel like by living that story as it's being told, it's like all these podcast listeners are also waiting for my like, you know, follow up, BKG, my blood results and all |
| 2:20.1 | of that. And I don't want anyone to have to have to. as it's being told. It's like all these podcast listeners are also waiting for my like, you know, follow-up |
| 2:18.5 | EKG, my blood results and all of that. And I don't want anyone to have to be on that waiting, scary journey with me. And I'm like, I'm sorry. No, that's life. It takes so much courage to tell your story while you're going through it because it's not like you're healthy now. You still have a major heart condition. you were still injecting yourself in the stomach with your new heart medication. |
| 2:36.2 | All that it is is that the worst, you still have a major heart condition. You were still injecting yourself in the stomach with your new |
| 2:34.5 | heart medication. All that it is is that the worst didn't happen. And we were in a moment where the |
| 2:40.6 | worst seemed like a 95% plus chance based on all of the probabilities we were given. So you got a cardiac |
| 2:46.1 | MRI back, which came back without myocarditis, which shocked the doctors. Everyone was just totally stunned. |
| 2:51.6 | I was convinced because I had it in 2021, and this felt very similar. |
| 2:54.8 | The test results were similar, and I was like, I have myocarditis. |
| 2:57.7 | Yes, what they thought, too. |
| 2:58.4 | And I was just, I honestly fully processed it until I got the cardiac at my results back. |
| 3:02.3 | And then it was clear, and I was like, what the fuck? |
... |
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