134 Endothelial glycocalyx
Veterinary Clinical Podcasts
Dominic Barfield
5 • 643 Ratings
🗓️ 30 September 2022
⏱️ 27 minutes
🧾️ Download transcript
Summary
Joining Brian and myself in our virtual studio we are delighted to have Dr Sara Lawrence-Mills, one of our fabulous residents in Anaesthesia and Analgesia here at the RVC. Sara has taken an interest into the endothelial glycocalyx and we thought we'd talk to her to find out why. We hope that you enjoy.
Some references of interest:
https://pubmed.ncbi.nlm.nih.gov/35654338/
https://www.frontiersin.org/articles/10.3389/fvets.2021.661660/full
https://pubmed.ncbi.nlm.nih.gov/22290457/
https://pubmed.ncbi.nlm.nih.gov/32067360/
To Cite this podcast as: Dom Barfield. RVC Clinical Podcast 134 Endothelial glycocalyx with Sara Lawrence-Mills. Published on September 30 2022
If you have any comments about this podcast, please get in touch: email [email protected]; tweet @dombarfield. We would greatly appreciate your time to rate us on Apple podcast, podbean or Acast and kindly write us a review.
Transcript
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| 0:00.0 | Good-Nay, Dominic Barfield here, and this is the RVC Clinical Podcast. Thank you for listening, |
| 0:03.9 | and thank you for subscribing on your smartphone or generic fruit-based device. And we're really |
| 0:08.0 | grateful for you to take the time to download and listen to this ABC podcast. We don't ask for much |
| 0:11.9 | in return, but we're incredibly grateful if you could pop to Apple podcast or ACAST, leave us a review. |
| 0:16.5 | Obviously, a five-story review would be great, but we'd greatly appreciate a couple minutes of your time to do that. |
| 0:24.7 | So today, joining Brian and myself in our virtual studio, we're going to talk to Sarah Lawrence Mills, |
| 0:31.2 | he's one of our first-year residents in Anesthesia and Algiersia here at the RBC. |
| 0:37.6 | Hello, Sarah. |
| 0:38.6 | Hello. How are you doing? |
| 0:40.5 | And what we thought we talked about is a bit about the glyca calyx because maybe, Sarah, |
| 0:46.8 | you can say how you got interested in the glyca calyx and, yeah. And maybe we can talk about what the glycaelix is as well |
| 0:57.4 | yeah maybe i'll start with what it what it is just to get people interested um so the glyca calyx |
| 1:03.8 | is a gel-like matrix and it covers the surface of lots of living things so bacteria fungus, fungus and some viruses, but the glycaelics |
| 1:14.5 | that I'm most important or interested in is the endothelial glycaelix. So that is the gel-like |
| 1:21.0 | matrix covering the inside of endothelial cells. I got interested in it, first of all, when I intercalated in health |
| 1:29.7 | sciences. So I did a kind of year out of the vet degree and was paired with a lovely supervisor |
| 1:35.2 | called Natalie Finch, who was obsessed with the glycalaucalyx and got me just as excited about it. |
| 1:40.8 | So what does it that get to you excited about the the glyca again? So it's really important in |
| 1:46.2 | maintaining vascular health but also just general health and there's really loads of growing |
| 1:52.3 | evidence in terms of how it contributes to the development of disease and the progression of disease |
| 1:58.0 | in lots of different disease states. So I think it's something, |
| 2:01.7 | it's microscopic, but it's really exciting and has a wide-reaching impact on our health. |
... |
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