Good day. Dominic Barfield here, and this is the RVC clinical podcast. Thank you for listening

and thank you for subscribing on your smartphone or generic fruit brace device. We're really

grateful for you taking the time to download and listen to this RVC podcast. And we don't

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So joining Brian and myself in our virtual studio, I've actually snuck into the real studio, but I won't tell Jack that.

We have a wonderful

Dr Jack Lawson, who's one of our lecturers in internal medicine here at the RVC. Hello, Jack.

Hello, nice to be here. That's very polite and understanding. And we thought we'd talk to you

about something that we believe is close to your heart. So it is the sort of

relationship between chronic kidney disease and hypotentia. Yes, I guess that is quite close to my

heart. I've done quite a bit of work on those two subjects and recently you kind of put together

an article linking the two of them.

So yeah, I think that's something that I do spend a lot of time thinking about and that I

think is quite important for practitioners to think about as well.

Great. So maybe if we could start at the start, so with regards to the kidney and regulation of blood pressure, so why is it important?

Well, I guess when we think about blood pressure, there's kind of two main organ systems at play.

There's the cardiovascular system, the heart, which we think about as primarily responsible for kind of the short-term regulation

of blood pressure, kind of second to second, minutes a minute.

And then we've got the kidneys as well, which we think about more as responsible for kind

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