Welcome to Helix Talk, a podcast presented by the Rosalm Franklin University College of Pharmacy.

This podcast is produced by pharmacy faculty to supplement study material and provide relevant drug and professional topics.

We're hoping that our real-life clinical pearls and discussions will help you stay up to date

and improve your pharmacy knowledge.

This is an educational production copyright Rosalind Franklin University of Medicine and Science.

This podcast contains general information for educational purposes only. This is not professional advice and should not be used in lieu of obtaining advice from a qualified health care provider.

And now, on to the show. Hi, Helix Talk listeners. This is Dr. Kane. After we released this episode, I received an email

updating us about the packaging for Debigotran brand name Prodaxa. So in this episode, we talk about

after the bottle for Prodaxas opened, it expires within four weeks. As it turns out, the labeling

was updated and now it is four months.

So again, the Bigotrain of Prodaxa once opened, expires after four months, not four weeks, as was described in this episode.

And now, on to the show.

Welcome to episode three of Helix Talk.

I'm your co-host, Dr. Kane. And I'm Dr. Patel,

and we're going to miss Dr. Schumann today. And today we're talking about the NOACs, or the novel

oral anticoagulants. There's three new ones on the market, and because they're new, we thought

that it would be a good topic to talk about today. I absolutely agree, especially people who are not familiar with this medications are kind of

confused as to which one is better or how they compare to the older ones, especially our good old

friend, Warfarin. Yeah, so unlike Warfarin, where Warfirm prevents the cladding cascade in a couple

different places, the NOACs work in one of two different places, either cladine factor

10 or the thing next to the cladding factor 10, which is cladine factor 2 or thrombin.

So we have our Prodaxa, generic is Zabigatran, and that is our direct factor 2 or direct thrombin

...