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High Intensity Health with Mike Mutzel, MS

Your Carb Tolerance Changes with Age, Here's Why

High Intensity Health with Mike Mutzel, MS

Mike Mutzel

Nutrition, Medicine, Health & Fitness

4.81.2K Ratings

🗓️ 23 September 2022

⏱️ 14 minutes

🧾️ Download transcript

Summary

Aging is linked with changes in your metabolism and carbohydrate tolerance, here’s the must-know details.

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Links to studies and videos mentioned: https://bit.ly/3C2aYhR

Shou, J., Chen, P.-J., & Xiao, W.-H. (2020). Mechanism of increased risk of insulin resistance in aging skeletal muscle. Diabetology & Metabolic Syndrome, 1–10.

Episode Time Stamps:


0:00 Your ability to process and tolerate carbohydrates declines with age.

0:40 Aging is linked with a decline in skeletal muscle insulin sensitivity.

1:45 Insulin resistance prevalence for those ages 40 to 59 is 40% to 60% and ages 20 to 39 is 20%. Over the age of 75, prevalence is over 75%.

2:35 Autophagy declines with age. There is a reduction in quantity and quality of mitochondria within the muscle, reduced insulin sensitivity and an increase in background inflammation.

03:20 Exercise increases mitophagy, the recycling of mitochondria.

4:45 Loss of fast twitch muscle fibers, associated with ageing, is associated with declines in insulin sensitivity and an increase in inflammation.

5:25 Over age 40, there is an 8% loss of muscle per decade. By age 70, your muscles are 30% smaller than age 20.

5:55 Loss of type 2 fibers causes a loss of strength.

6:20 Strength loss is 25 to 40% per decade after the age of 40. Muscle size lost is about 10% per decade over 40.

6:55 Exercise to improve metabolic health.

7:50 Do explosive, high intensity movements and compound multi muscle movements.

9:40 Periodically, focus on strength, speed, and concentric movement to prevent the preferential loss of type 2 fibers.

13:25 Exercise reduces blood pressure and increases autophagy and mitophagy.

Transcript

Click on a timestamp to play from that location

0:00.0

As you age your ability to process and tolerate carbohydrates declines.

0:03.7

In today's session, what we're going to do is talk more about that process,

0:06.2

known as age-associated insulin resistance.

0:09.5

And then we're going to focus on the ways that you can potentially reverse

0:12.8

this age-associated insulin resistance that actually occurs within your skeletal muscle.

0:17.6

Now, as we talk about this, I think it's important to recognize that

0:20.8

one of the major shortcomings of the low calorie diet community,

0:24.4

people that will say, well, a calorie is a calorie is a calorie.

0:27.5

It doesn't really matter what you eat so long as you're in a deficit

0:30.9

if you want to lose weight or you're in a surplus if you want to gain weight.

0:34.9

The sort of nuance that's omitted from that conversation is the data showing

0:40.0

objectively, clearly through many different populations and ethnicities

0:44.8

that aging is linked with a decline in skeletal muscle insulin sensitivity.

0:49.9

And so therefore, we should apply different contexts of diets and apply,

0:54.8

help people better understand their carbohydrate tolerance and custom tailor a diet

0:59.5

that is commensurate with their age and their activity level.

1:02.8

If you're a little bit older and you're not very physically active,

1:06.4

the notion of a calories, a calorie is a calorie,

1:08.9

well, what if you're eating a diet that's rich in carbohydrates and you're not physically active

1:13.2

and you know that you're insulin resistant? It makes a little bit more sense to have a lower

1:17.7

carbohydrate diet in that particular context. So I think the nuance gets lost.

1:22.0

Only classic calories and calories out model, the seco model.

...

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